- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Stress Responses and Cortisol
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Anesthesia and Sedative Agents
- Thermal Regulation in Medicine
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Healthcare Decision-Making and Restraints
- Hip and Femur Fractures
- Healthcare professionals’ stress and burnout
- Immune responses and vaccinations
- Acute Kidney Injury Research
- Respiratory viral infections research
- Drug-Induced Hepatotoxicity and Protection
- Pediatric Pain Management Techniques
- Family and Patient Care in Intensive Care Units
- Respiratory Support and Mechanisms
- Inflammatory mediators and NSAID effects
- Anesthesia and Neurotoxicity Research
- Tryptophan and brain disorders
- Hemodynamic Monitoring and Therapy
Pomeranian Medical University
2018-2023
Since the end of 2019, whole world has been struggling with pandemic new Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Available evidence suggests that pain is a common symptom during Disease 2019 (COVID-19). According to World Health Organization, many patients suffer from muscle (myalgia) and/or joint (arthralgia), sore throat and headache. The exact mechanisms headache myalgia viral infection are still unknown. Moreover, respiratory failure get admitted intensive care unit...
Importance Nearly 16 million surgical procedures are conducted in North America yearly, and postoperative cardiovascular events frequent. Guidelines suggest functional capacity or B-type natriuretic peptides (BNP) to guide perioperative management. Data comparing the performance of these approaches scarce. Objective To compare addition either N-terminal pro-BNP (NT-proBNP) self-reported clinical scores estimate risk major adverse cardiac (MACE). Design, Setting, Participants This cohort...
Intubation time in patients undergoing cardiac surgery may be associated with increased mortality and morbidity. Premature extubation can have serious adverse physiological consequences. The aim of this study was to determine the influence intubation on morbidity surgery.We performed a retrospective analysis data 1,904 isolated coronary artery bypass grafting (CABG) stratified them by duration after - 0-6, 6-9, 9-12, 12-24 over 24 hours. Postoperative complications risk using multivariate...
Background: Postoperative delirium (POD) is a serious complication of cardiac surgery. It an acute neuropsychiatric syndrome. The aim this study was to analyze the CARDEL Index, composed advancing age, preoperative glycated hemoglobin and platelet-to-WBC ratio (PWR) previously described calculated, using different patient database, assess its usefulness as marker for predicting postoperative after coronary artery by-pass grafting (CABG). Methods: A retrospective analysis 1098 patients who...
Background and Objectives: The incidence of postoperative delirium (POD) in patients with chronic obstructive pulmonary disease (COPD) is unclear. It seems that respiratory problems may occur COPD patients, including prolonged mechanical ventilation or respiratory-tract infections, contribute to the development delirium. aim study was identify a relationship between occurrence after cardiac surgery impact these combined disorders on mortality. Materials Methods: We performed an analysis data...
In December 2019 the SARS-CoV-2 virus appeared in world, mainly presenting as an acute infection of lower respiratory tract, namely pneumonia. Nearly 10% all patients show significant pulmonary fibrotic changes after infection. The aim this study was to evaluate effectiveness and safety potassium canrenoate treatment COVID-19-associated pneumonia fibrosis. We performed a randomized clinical trial (RCT) vs placebo. A total 55 were 49 included final analysis (24 allocated intervention group 25...
Background and objectives: Adequate pain management is a major challenge of public health. The majority students graduating from medical schools has insufficient education experience with patients suffering pain. Not enough being taught regarding in non-verbal (children, critically ill the intensive care unit, demented). Chronic most difficult to optimize requires appropriate preparation at level school. Our aim was evaluate attitudes, expectations actual knowledge different levels their...
In March 2020, the World Health Organization (WHO) announced a global pandemic of coronavirus disease 2019 (COVID-19) that presented mainly as an acute infection lower respiratory tract (pneumonia), with multiple long-term consequences, including lung fibrosis. The aim this study was to evaluate influence potassium canrenoate on inflammatory markers in treatment COVID-19 pneumonia. A randomized clinical trial (RCT) intravenous vs. placebo performed between December 2020 and November 2021....
Background: Recent studies have shown that methylation changes identified in blood cells of COVID-19 patients a potential to be used as biomarkers SARS-CoV-2 infection outcomes. However, different reported subsets epigenetic lesions stratify according severity symptoms, and more importantly, the significance those pathology is still not clear.Methods: We methylomics transcriptomics data from largest so far cohort four geographically distant populations identify casual interactions cells’...