A5080867678- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Veterinary Equine Medical Research
- Meat and Animal Product Quality
- Chromosomal and Genetic Variations
- Genetic diversity and population structure
- Circular RNAs in diseases
- Medicinal Plant Pharmacodynamics Research
- Genomics and Phylogenetic Studies
- Muscle metabolism and nutrition
- Immunotherapy and Immune Responses
- Rangeland Management and Livestock Ecology
- Genetics and Physical Performance
- Animal Genetics and Reproduction
- Plant and fungal interactions
- Rabbits: Nutrition, Reproduction, Health
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Diversity and Health Studies
- Animal Nutrition and Physiology
- Molecular Biology Techniques and Applications
- Neurological diseases and metabolism
- Cassava research and cyanide
- vaccines and immunoinformatics approaches
- Monoclonal and Polyclonal Antibodies Research
Plusvital (Ireland)
2019-2025
Inner Mongolia Agricultural University
2014-2024
University College Dublin
2019-2022
Ministry of Agriculture and Rural Affairs
2019-2021
China Agricultural University
2008-2021
Experimental Station
2020
In a commercial hatchery, chicks (or poults) hatch over 24–48 hour period. All remain in the incubator until majority of have emerged from shell. Once removed incubator, newly hatched chick has to undergo several hatchery treatments and is then transported before being placed on broiler farm. This means that, under practical conditions, are deprived feed water for up 72 hours. addition, time within hatching window spread cause variability amount that deprived. Literature deprivation after...
Abstract Background Equine recurrent laryngeal neuropathy (RLN) is an economically important upper respiratory tract (URT) disease with a genetic contribution to risk, but variants independent of height have not been identified for Thoroughbreds. The method clinical assessment RLN critical accurately phenotype groups studies. Objectives To identify risk loci in Thoroughbreds genome‐wide association study (GWAS) following high‐resolution phenotyping. Study design Case–control. Methods...
Temperatures continuously higher and lower than the standard incubation temperature by 3°C from embryonic d 16 until 18.5 result in differential effects on development, hatching process, metabolism. Embryos high-temperature group were forced into a state of malnutrition treatment, as reflected reduced embryo growth yolk consumption, resulting significantly chick weight at hatch. In addition, altered air cell blood gases well retarded process further indicated embryos exposed to temperatures...
Karyotypic diversification is more prominent in Equus species than other mammals. Here, using next generation sequencing technology, we generated and de novo assembled quality genomes sequences for a male wild horse (Przewalski's horse) domestic (Mongolian horse), with about 93-fold 91-fold coverage, respectively. Portion of Y chromosome from assemblies (3 M bp) Mongolian (2 were also sequenced assembled. We confirmed Robertsonian translocation event through the horse's chromosomes 23 24,...
The Thoroughbred horse is a highly valued domestic animal population under strong selection for athletic phenotypes. Here we present high resolution genomics-based analysis of inbreeding in the that may form basis evidence-based discussion amid concerns breeding industry over increasing use small numbers popular sire lines, which accelerate loss genetic diversity. In most comprehensive globally representative sample Thoroughbreds to-date (n = 10,118), including prominent stallions 305) from...
Abstract Background Thousands of years natural and artificial selection since the domestication horse has shaped distinctive genomes Chinese Mongolian populations. Consequently, genomic signatures can provide insights into human-mediated history specific traits evolutionary adaptation to diverse environments. Here, we used genome-wide SNPs from five distinct populations identify regions under for population-specific traits, gait, black coat colour, hoof quality. Other global breeds were...
The Y chromosome carries information about the demography of paternal lineages, and thus, can prove invaluable for retracing both evolutionary trajectory wild animals breeding history domesticates. In horses, shows a limited, but highly informative, sequence diversity, supporting increasing influence Oriental lineages during last 1500 years. Here, we augment primary horse Y-phylogeny, which is currently mainly based on modern breeds economic interest, with haplotypes (HT) segregating in...
The donkey, like the horse, is a promising model for exploring karyotypic instability. We report de novo whole-genome assemblies of donkey and Asiatic wild ass. Our results reflect distinct characteristics donkeys, including more effective energy metabolism better immunity than horses. shows steady demographic trajectory. detected abundant satellite sequences in some inactive centromere regions but not neocentromere regions, while ribosomal RNAs frequently emerged obsolete regions. Expanded...
Abstract Selection for system-wide morphological, physiological, and metabolic adaptations has led to extreme athletic phenotypes among geographically diverse horse breeds. Here, we identify genes contributing exercise adaptation in racehorses by applying genomics approaches racing performance, an end-point phenotype. Using integrative strategy first combine population results with skeletal muscle training transcriptomic data, followed whole-genome resequencing of Asian horses,...
Abstract Uncontrolled crossbreeding is a major challenge to the conservation of landrace horses in East Asia. Understanding factors driving this trend crucial for effective efforts. Here, we investigate genomic makeup 40 Mongolian Naadam racehorses and 21 Asian horse breeds through analyzing whole‐genome resequencing Y chromosome data. Our results show that practices are linked horse‐racing traditions. Regions characterized by strong traditions lack regulations exhibit significant levels...
Behavioural plasticity enables horses entering an exercise training programme to adapt with reduced stress. We characterised SNPs associated behaviour in yearling Thoroughbred using genomics analyses for two phenotypes: (1) handler-assessed coping early events [coping] (n = 96); and (2) variation salivary cortisol concentration at the first backing event [cortisol] 34). Using RNA-seq derived gene expression data amygdala hippocampus tissues from n 2 stallions, we refined those functional...
The Mongolian horse represents one of the most ancient extant populations. In this study we determined male-specific region Y chromosome (MSY) haplotype distribution in 60 Chinese horses representing five distinct Cosmopolitan male lineages were predominant from improved (Sanhe), subtype (Baicha Iron Hoof) and indigenous (Abaga Black) population. contrast, autochthonous diversity was evident among two landrace populations (Wushen Wuzhumuqin), as majority their MSY haplotypes situated at root...
Skeletal muscle is the largest organ system in mammalian body and plays a key role locomotion of horses. Fast slow fibers have different abilities functions to adapt exercises. To investigate RNA miRNA expression profiles muscles with fiber compositions on Mongolian We examined type population produced deep sequencing for parts skeletal muscles. And chose two them highest difference fast (splenius gluteus medius) comparing gene profile types. identified total 275 differentially expressed...
Thoroughbred horse racing is a global sport with major hubs in Europe, North America, Australasia and Japan. Regional preferences for certain traits have resulted phenotypic variation that may result from adaptation to the local ecosystem. Here, we test hypothesis genes selected regional be identified by analysis of selection signatures pan-genomic SNP genotype data. Comparing Australian non-Australian horses (n = 99), most highly differentiated loci composite signals (CSS) were on ECA6...
The Mongolian horse is one of the oldest extant populations and although domesticated, most animals are free-ranging experience minimal human intervention. As an ancient population originating in key domestication centers, may play a role understanding origins recent evolutionary history horses. Here we describe analysis high-density genome-wide single-nucleotide polymorphism (SNP) data 40 globally dispersed (n = 895). In particular, have focused on new results from Chinese horses 100) that...
Avian blastodermal cells at stage X are used to produce interspecies chimeras for heterogenous poultry reproduction. However, recipient-derived inner perivitelline layer (IPVL)-enclosed donor-derived ova may affect the efficiency of germline transmission via chimera. Among proteins in IPVL, zona pellucida protein C (ZPC) plays an important role sperm-egg binding and inducing acrosome reaction. In present study, Peking duck were transferred into subgerminal cavities Japanese quail embryos...
The Mongolian horse, one of the oldest and most genetically diverse breeds, exhibits a wide variety coat colors patterns, including both wild-type unique features. A notable characteristic dun horses is presence Bider markings-symmetrical, black-mottled patterns observed on shoulder blades. These markings are also seen in Przewalski's horses. color, common phenotype domestic horses, characterized by pigment dilution with distinct dark areas regulated mutations Skin tissue samples were...
Throughout human history, the horse (Equus ferus caballus) was often involved in cultural exchanges and development of various societies.Human activities has directly indirectly impacted evolution domestic horses, especially since industrial revolution.There been extensive research into when horses were originally domesticated how humans horse's genetic during domestication.Recent developments genomic technology advanced our understand evolution.This review summarizes results last 20 years...
Abstract Background Different morphological structures of hairs having properties like defense and camouflage help animals survive in the wild environment. Horse is one rare kinds with complex hair phenotypes individual; however, knowledge horse follicle limited literature their molecular basis remains unclear. Therefore, investigation morphogenesis pigmentogenesis attracts considerable interest. Result Histological studies revealed morphology pigment synthesis follicles are different...