Takanori Sasaki

ORCID: 0000-0002-0821-827X
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Research Areas
  • Game Theory and Applications
  • Radiopharmaceutical Chemistry and Applications
  • Evolutionary Game Theory and Cooperation
  • Computability, Logic, AI Algorithms
  • Complex Systems and Time Series Analysis
  • Bone health and treatments
  • Nanoparticle-Based Drug Delivery
  • Chemical Synthesis and Characterization
  • Distributed and Parallel Computing Systems
  • COVID-19 Clinical Research Studies
  • Privacy, Security, and Data Protection
  • SARS-CoV-2 and COVID-19 Research
  • Multi-Agent Systems and Negotiation
  • Monoclonal and Polyclonal Antibodies Research
  • E-Government and Public Services
  • Internet Traffic Analysis and Secure E-voting
  • Economic theories and models
  • SARS-CoV-2 detection and testing
  • Medical Imaging and Pathology Studies

Okayama University
2023-2025

Universitätsklinikum Würzburg
2024

Iwate Prefectural University
2007

National Defense Academy of Japan
1998-2002

The Omicron variant continuously evolves under the humoral immune pressure exerted by vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, resulting subvariants display further evasion antibody escape. An engineered angiotensin-converting enzyme (ACE2) decoy composed of high-affinity ACE2 an IgG1 Fc domain could offer alternative modality to neutralize SARS-CoV-2. We previously reported its broad spectrum therapeutic potential in rodent models. Here, we...

10.1126/scitranslmed.adi2623 article EN Science Translational Medicine 2023-08-30

Thin-layer chromatography (TLC) is commonly employed to screen technetium-99m labeled polymer nanoparticle batches for unreduced pertechnetate and radio-colloidal impurities. Although this method widely accepted, our findings applying radiolabeled PLGA/PLA-PEG nanoparticles underscore its lack of transferability between different settings limitations as a standalone quality control tool. While TLC profiles may appear similar purified radiocolloid containing formulations, their in vivo...

10.1021/acsptsci.4c00383 article EN cc-by ACS Pharmacology & Translational Science 2024-08-30

Many local governments have been actively promoting implementation of their services and information systems in various ways. The main issues this approach are "how e-local can manage effectively" "be more citizen-oriented". In paper, focusing on the latter, we surveyed administrative channels to improve citizen satisfaction with CiRM (citizen relationship management), which applies CRM (customer management) for private sector government management. Then specially introduced contact center,...

10.1109/picmet.2007.4349624 article EN 2007-08-01

In this research, we aim at building the competitive evolutional model. We term such an agent with both a selfish-motivation and social competence as rational or self-interested agent. especially provide model for investigating collective behaviors that are emerged from local interactions among those agents. formulate knowledge transaction methodology of interaction They transact each other by exchanging their valuable private knowledge. The exchanged is shared agents common in same group....

10.1109/icec.1998.699117 article EN 2002-11-27

<title>Abstract</title> Background Preclinical pharmacokinetic studies of therapeutic antibodies in non-human primates are desired because the difficulty extrapolating ADME data from animal models to humans. We evaluated pharmacokinetics <sup>89</sup>Zr-labelled anti-KLH human IgG and its metabolites confirm their non-specific/physiological accumulation healthy cynomolgus macaques. Methods Selected was conjugated desferrioxamine (DFO), labelled with <sup>89</sup>Zr, injected into macaques...

10.21203/rs.3.rs-4258167/v1 preprint EN cc-by Research Square (Research Square) 2024-04-23

In this research, we provide a model of decentralized computation based on the principle market mechanism. Market agents are defined as autonomous software entities with functions self-interest seeking. They have their own computational capabilities utility over We obtain equilibrium solutions in context individual optimal behavior each agent. dynamic adaptive agent's interest discuss how an solution can be obtained through computation. also describe collective those and show that stability...

10.1002/(sici)1520-684x(19981130)29:13<1::aid-scj1>3.0.co;2-d article EN Systems and Computers in Japan 1998-11-30

In this research, we provide a model of decentralized computation based on the principle market mechanism. Market agents are defined as autonomous software entities with functions self-interest seeking. They have their own computational capabilities utility over We obtain equilibrium solutions in context individual optimal behavior each agent. dynamic adaptive agent's interest discuss how an solution can be obtained through computation. also describe collective those and show that stability...

10.1002/(sici)1520-684x(19981130)29:13<1::aid-scj1>3.3.co;2-4 article EN Systems and Computers in Japan 1998-11-30
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