- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Dietary Effects on Health
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Neurological and metabolic disorders
- Dialysis and Renal Disease Management
- Healthcare cost, quality, practices
- Metabolism, Diabetes, and Cancer
Empowerment Program
2024
Weill Cornell Medicine
2020-2023
Cornell University
2020-2023
Health Economics and Outcomes Research (United Kingdom)
2020
Albert Einstein College of Medicine
2007-2012
CD8(+) T-cells specific for islet antigens are essential the development of type 1 diabetes in NOD mouse model disease. Such can also be detected blood diabetic patients, suggesting their importance pathogenesis human disease as well. The peptide-based therapeutic reagents that target islet-reactive will require identification disease-relevant epitopes.We used islet-infiltrating from HLA-A*0201 transgenic mice an interferon-gamma enzyme-linked immunospot assay to identify autoantigenic...
The development of minimally invasive continuous glucose monitoring systems (CGMs) has transformed diabetes management. CGMs have shown clinical significance by improving time in the euglycemic range, decreasing rates hypoglycemia, and HbA1c. In Rwanda, are currently not routine use, no studies CGM use were identified literature. To determine impact feasibility real-time among people living with T1D through assessment sensor usage, hypo-and-hyperglycemia, HbA1c diabetes-related...
Type 1 diabetes is an autoimmune disease characterized by T cell responses to β Ags, including insulin. Investigations employing the NOD mouse model of have revealed essential role for cell-specific CD8(+) cells in pathogenic process. As specific Ags are also present patients, these reactivities potential serve as therapeutic targets or markers activity. mice transgenic human class I MHC molecules previously been employed identify epitopes having important relevance disease. However, most...