A5002992838- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Renal and related cancers
- Urinary and Genital Oncology Studies
- Cancer-related Molecular Pathways
- Urologic and reproductive health conditions
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Urological Disorders and Treatments
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Surgical site infection prevention
- Multiple and Secondary Primary Cancers
- Prostate Cancer Diagnosis and Treatment
- Genetic and Kidney Cyst Diseases
- Pediatric Urology and Nephrology Studies
- Ferroptosis and cancer prognosis
- Ear and Head Tumors
- Gastrointestinal Tumor Research and Treatment
- Cancer-related molecular mechanisms research
- Total Knee Arthroplasty Outcomes
- Oral and Maxillofacial Pathology
Universitat de Barcelona
2005-2022
Hospital Clínic de Barcelona
2001-2022
Universitat Autònoma de Barcelona
2017
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2001-2013
Puigvert Foundation
2004
Abstract STUDY QUESTION Are epididymosomes implicated in protein transfer from the epididymis to spermatozoa? SUMMARY ANSWER We characterized contribution of epididymal secretions sperm proteome and demonstrated that acquire proteins through epididymosomes. WHAT IS KNOWN ALREADY Testicular are immature cells unable fertilize an oocyte. After leaving testis, transit along motility fertilizing abilities. It is well known marked changes profile occur during maturation. Since a transcriptional...
Abstract Objective Neovascularization, with an increased number of synovial vessels a characteristic morphology, seems to contribute the progression psoriatic arthritis (PsA). Accordingly, angiogenesis may be important therapeutic target in PsA. The aim this study was analyze effects infliximab on membrane patients PsA who responded therapy. Methods group comprised 9 were selected for presence active polyarthritis (including knee synovitis) despite methotrexate Clinical and biologic...
Aims: Adenosquamous carcinoma (ASC) of the head and neck is an unusual neoplasm in which a general consensus with regard to diagnostic criteria has not yet been reached. In this study we report clinicopathological results 12 ASCs, special attention their histological immunohistochemical characteristics order define more precisely. Methods results: All patients were male peak incidence sixth decade life. The tumours located most frequently larynx oral cavity, followed by nasal cavity pharynx....
The overexpression of c-Kit in chromophobe renal cell carcinoma (ChRCC) has been described by comparative gene expression analyses and proposed as a possible specific hallmark this neoplasm. aim our study was to establish its immunohistochemical large series ChRCC compare it with other neoplasms. In study, characterization KIT performed 87 neoplasms including 25 cases ChRCC, 13 oncocytoma, 39 carcinomas (21 conventional RCC [CRCC], 8 CRCC granular differentiation, 10 papillary [PRCC])....
Appropriate interpretation of a frozen section has relatively high specificity and sensitivity for the diagnosis infection when septic loosening prosthesis is suspected. However, its usefulness predicting presence microorganisms at time reimplantation after hip resection arthroplasty treatment not well defined. The aim present study was to evaluate histological analysis in this situation.From January 2002 February 2006, total twenty-one patients underwent infection. Histological studies...
To assess the accuracy contrast-enhanced ultrasound (CEUS) in bladder cancer detection using transurethral biopsy conventional cystoscopy as reference standard and to determine whether CEUS improves rate of baseline ultrasound.43 patients with suspected underwent suspicious lesions. 64 cancers were confirmed 33 out 43 patients. Baseline performed day before surgery both techniques for number detected tumours analysed compared final diagnosis.CEUS was significantly more accurate than...
Cyclin D1 (CCND1) and retinoblastoma (Rb) genes are cell cycle regulators which altered in some breast carcinomas. However, the possible cooperation between CCND1 Rb, as well influence coincidence of their abnormalities proliferative capacity mammary carcinoma cells vivo, is still unknown. In order to assess both significance gene Rb alterations carcinomas relationship with tumours other clinico-pathological factors, mRNA expression was studied 46 cases primary matched normal tissue, 45 were...
cdc25 is a family of cell-cycle phosphatases that activate the cyclin-dependent kinases. cdc25A and B, but not C, have oncogenic potential in vitro. In this study, we analyzed possible implication genes progression colorectal tumors. RNA DNA were extracted from 34 paired tumor normal tissues examined by Northern blot, RT-PCR, Southern respectively. Protein expression was Western blot subset samples. The levels correlated with clinicopathologic characteristics survival patients. cdc25B mRNA...
p53 expression has been examined in 89 squamous cell carcinomas of the larynx (34 glottic, 28 supraglottic, 18 transglottic, 8 pyriform sinus, and 1 subglottic) obtained from 88 patients surgically treated our centre. In addition, 59 laryngeal samples including normal respiratory epithelium non-invasive lesions were also tested. Frozen sections immunostained with PAb 1801 results correlated pathological features, DNA ploidy S-phase tumours, disease-free interval, survival patients....
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jun 2004C-KIT EXPRESSION IN SARCOMATOID RENAL CELL CARCINOMA: POTENTIAL THERAPY WITH IMATINIB MIREIA CASTILLO, ANNA PETIT, BEGOÑA MELLADO, ANTONIO PALACÍN, JOAN B. ALCOVER, and CARME MALLOFRÉ CASTILLOMIREIA CASTILLO More articles by this author , PETITANNA PETIT MELLADOBEGOÑA MELLADO PALACÍNANTONIO PALACÍN ALCOVERJOAN ALCOVER MALLOFRÉCARME View All Author Informationhttps://doi.org/10.1097/01.ju.0000127727.33232.cfAboutFull...
Background: Appropriate interpretation of a frozen section has relatively high specificity and sensitivity for the diagnosis infection when septic loosening prosthesis is suspected. However, its usefulness predicting presence microorganisms at time reimplantation after hip resection arthroplasty treatment not well defined. The aim present study was to evaluate histological analysis in this situation. Methods: From January 2002 February 2006, total twenty-one patients underwent infection....
p21WAF1/Cip1 is an inhibitor of cdk/cyclin complexes, and thus regulates the cell cycle. p21 also related to differentiation regulated by wild-type p53, although p53-independent regulatory pathways have been proposed. In order analyse expression as well its relationship with p53 in human breast cancer, immunohistochemical analysis was undertaken 77 carcinomas, 16 them situ component; 30 adjacent normal tissue samples; five non-neoplastic specimens. Forty-four infiltrating carcinomas (57 per...
p21WAF1/Cip1 is a recently identified gene involved in cell cycle regulation through cyclin-CDK-complex inhibition. The expression of this several lines seems to be induced by wild-type, but not mutant, p53. has been studied at both mRNA and protein levels series 49 normal mucosae squamous carcinomas the larynx. A significant association was found between tumours (P<0·0001). strongly associated with differentiation carcinomas, because six seven (86 per cent) undifferentiated (grade 4) showed...
Our aim was to define seminal plasma proteome signatures of infertile patients categorized according their parameters using TMT-LC-MS/MS. To that extent, quantitative proteomic data analyzed following two complementary strategies: (1) the conventional approach based on standard statistical analyses relative protein quantification values; and (2) a novel strategy focused establishing stable-protein pairs. By analyses, abundance some proteins found be positively correlated with sperm...