A5049809963- Glioma Diagnosis and Treatment
- Signaling Pathways in Disease
- RNA modifications and cancer
- Neuroblastoma Research and Treatments
- ATP Synthase and ATPases Research
- Chemical Reactions and Isotopes
- Prostate Cancer Treatment and Research
- Cancer Research and Treatments
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
- NF-κB Signaling Pathways
- Cytokine Signaling Pathways and Interactions
- Traumatic Ocular and Foreign Body Injuries
- Hormonal and reproductive studies
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Child Abuse and Related Trauma
- Metabolism, Diabetes, and Cancer
- Prostate Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Ubiquitin and proteasome pathways
- Histone Deacetylase Inhibitors Research
- MicroRNA in disease regulation
- Mathematical Biology Tumor Growth
- RNA Research and Splicing
Xuzhou Medical College
2019-2022
Xuzhou Children Hospital
2017-2018
Boston Children's Hospital
2015
Jiangsu University
2010
The rapid development of metastatic lesions remains the leading cause mortality for patients with osteosarcoma. CD155 serves a key role in cancer cell migration, invasion and metastasis. However, function mechanism has not been explored osteosarcoma In present study, we found that was significantly upregulated lung tissue highly line K7M2-WT (K7M2) Overexpression K7M2 cells enhanced metastasis, while inhibition by an anti-CD155 monoclonal antibody reduced Blocking also decreased migration...
The ubiquitin ligase ring finger protein 5 (RNF5) has previously been associated with the development of breast cancer. Patients cancer and high RNF5 expression have demonstrated to a shorter survival time compared patients low expression. However, role in human glioma not determined. present study analyzed gliomas using bioinformatics analysis. results revealed that was differentially expressed non-cancerous brain tissues different grades glioma. Furthermore, an improved prognosis Gene Set...
Gliomas are the most common primary brain tumors. Because of their high degree malignancy, patient survival rates unsatisfactory. Therefore, exploring glioma biomarkers will play a key role in early diagnosis, guiding treatment, and monitoring prognosis gliomas. We found two lncRNAs, six miRNAs, nine mRNAs that were differentially expressed by analyzing genomic data patients. The diagnostic value mRNA expression levels gliomas was determined receiver operating characteristic (ROC) curve...
Approximately 25% of osteosarcoma patients present with clinically detectable metastatic disease at the time initial diagnosis. High-dose chemotherapy and/or surgery for treatment primary is ineffective, and <20% will survive 5 years from Therefore, metastases critical improvement prognosis patients. We have previously observed that overexpression interleukin-24 (IL-24) inhibits neuroblastoma cell proliferation, migration invasion in vitro. The study investigated whether IL-24 may be a novel...
The determination of plausibility an injury arising from a fall leading to head trauma is great challenge especially in young children. present review aimed discuss important developments the filed cases We explored various studies pertaining injuries children by exploring mainly PubMed, Google scholar and some library periodicals available our library. Studies recent past as result low height fall. However, there are amount difficulties assessment with certainty that caused like skull...
Pediatrics brain tumours are the second most frequent malignancy in children, and common cause of cancer-related deaths both 0-14-year 15-24-year age group. Although, pediatrics high-grade glioma (pHGG) is a histologically similar tumour to that arising adults, these distinct biological diseases, differing copy number profiles driver genetic alterations. Recent sequencing initiatives have conclusively shown existence subgroups HGG marked by mutations, which significantly enriched young...
Pediatrics brain tumors are the second most frequent malignancy in children, and common cause of cancer-related deaths both 0-14-year 15-24-year age group. Although, pediatrics high-grade glioma (pHGG) is a histologically similar tumor to that arising adults, these distinct biological diseases, differing copy number profiles driver genetic alterations. Recent sequencing initiatives have conclusively shown existence subgroups HGG marked by mutations, which significantly enriched young...