A5100689573- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Plasmonic and Surface Plasmon Research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Chemical Sensor Technologies
- Luminescence and Fluorescent Materials
- Photochromic and Fluorescence Chemistry
- Aluminum Alloys Composites Properties
- Plant and animal studies
- Soil Carbon and Nitrogen Dynamics
- Pregnancy and preeclampsia studies
- Advanced Sensor and Control Systems
- Industrial Technology and Control Systems
- Acoustic Wave Resonator Technologies
- Magnesium Alloys: Properties and Applications
- Optical Imaging and Spectroscopy Techniques
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Chalcogenide Semiconductor Thin Films
- Phosphorus and nutrient management
- Numerical methods in engineering
- Water Quality Monitoring and Analysis
- Electronic Packaging and Soldering Technologies
- Pregnancy and Medication Impact
Affiliated Eye Hospital of Wenzhou Medical College
2022-2025
Wenzhou Medical University
2020-2025
Kunming University of Science and Technology
2024-2025
Guangxi Academy of Special Crops
2024
University of Chinese Academy of Sciences
2020-2024
First People's Hospital of Yunnan Province
2024
Central South University
2006-2024
Shanghai Advanced Research Institute
2023
Chinese Academy of Sciences
2023
ShanghaiTech University
2023
Abstract Biopsy is the recommended standard for pathological diagnosis of liver carcinoma. However, this method usually requires sectioning and staining, well-trained pathologists to interpret tissue images. Here, we utilize Raman spectroscopy study human hepatic samples, developing validating a workflow in vitro intraoperative cancer. We distinguish carcinoma tissues from adjacent non-tumour rapid, non-disruptive, label-free manner by using combined with deep learning, which validated...
The eye contains a wealth of physiological information and offers suitable environment for noninvasive monitoring diseases via smart contact lens sensors. Although extensive research efforts recently have been undertaken to develop sensors, they are still in an early stage being utilized as intelligent wearable sensing platform various biophysical/chemical conditions. In this review, we provide general introduction lenses that developed disease therapy. First, different biomarkers available...
We report on a smartphone spectrometer for colorimetric detection of glucose and cardiac troponin I.
Peptide-functionalized gold nanoparticles (AuNPs) are extensively utilized in colorimetric assays for rapid and sensitive detection of various biomedical environmental targets. Although used as reporting systems, the role size concentration AuNPs has not been thoroughly investigated. In this study, a 12-mer cardiac troponin I (cTnI)-specific peptide CALNN-Peg4-FYSHSFHENWPS was immobilized on different via CALNN anchoring sequence. A relationship established between total surface area...
SERS-based breath analysis as an emerging technique has attracted increasing attention in cancer screening. Here, eight aldehydes and ketones the human are reported VOC biomarkers identified by gas chromatography–mass spectrometry (GC-MS) applied further for noninvasive diagnosis of gastric (GC) with a tubular SERS sensor. The sensor is prepared glass capillary loaded ZIF-67-coated silver particles (Ag@ZIF-67), which offers Raman enhancement from plasmonic nanoparticles enrichment...
Contact lenses have become a popular health-monitoring wearable device due to their direct contact with the eyes. By integrating biosensors into lenses, real-time and noninvasive diagnoses of various diseases can be realized. However, current lens sensors often require complex electronics, which may obstruct user's vision or even damage cornea. Moreover, most reported only detect one analyte. Therefore, an optical-based dual-functional smart sensor has been introduced monitor intraocular...
Abstract An atomically thin TaSe 2 sample, approximately containing two to three layers of nanosheets with a diameter 2.5 cm is prepared here for the first time and applied on detection various Raman‐active molecules. It achieves limit 10 −10 m rhodamine 6G The excellent surface‐enhanced Raman scattering (SERS) performance underlying mechanism are revealed using spectrum analysis density functional theory. large adsorption energy abundance filled electrons close Fermi level found play...
Botulinum neurotoxin is considered as one of the most toxic food-borne substances and a potential bioweapon accessible to terrorists. The development an accurate, convenient, rapid assay for botulinum neurotoxins therefore highly desirable addressing biosafety concerns. Herein, novel biotinylated peptide substrates designed mimic synaptosomal-associated protein 25 (SNAP-25) are utilized in gold nanoparticle-based assays colorimetric detection serotype A light chain (BoLcA). In these...
Mixed-species flocks of birds are distributed world-wide and can be especially dominant in temperate forests during the non-breeding season tropical rainforests year-round. We review from a community ecology perspective what is known about structure organization flocks, emphasizing that flocking species tend to those particularly vulnerable predation, led by able act as sources information predators for other species. Studies on how respond fragmentation land-use intensification continue...
Localized surface plasmon resonance (LSPR) constitutes a versatile technique for biodetection, exploiting the sensitivity of plasmonic nanostructures to small changes in refractive index. The optical shift LSPR band caused by molecular interactions vicinity are typically <5 nm and can readily be detected spectrophotometer. Widespread use LSPR-based sensors require cost-effective devices would benefit from sensing schemes that enables very simple spectrophotometers or even naked-eye...
Retinal dopamine is believed to be involved in the development of myopia, which projected affect almost half world population's visual health by 2050. Direct visualization retina with high spatial precision essential for understanding biochemical mechanism during myopia. However, there are very few approaches direct detection system, particularly retina. Here, we report surface-enhanced Raman scattering (SERS)-based imaging cells and retinal tissues precision. The surface gold nanoparticles...
Background The causal association between blood uric acid and preeclampsia (Preeclampsia, PE) has not been conclusively established based on the literature reviewed to date. This bi-directional Mendelian randomization study aimed investigate concentration PE at different genetic levels.
Yb: CaGdAlO 4 (Yb: CALGO) single crystals having a series of Yb 3+ concentrations (0.5, 1.7, 2.5, 5.0, 7.2, and 8.0 at%) were grown using the Czochralski method. X-ray powder diffraction (XRD),...
Wearable sweat sensors offering real-time monitoring of biomarker levels suffer from stability and accuracy issues, primarily due to low concentrations, fluctuating pH, material detachment sensor deformation. Here, we developed a wearable sensing system integrated with two advanced electrodes flexible microchannel for long-term reliable pH uric acid (UA). By printing the ink doped nanomaterials (Co3O4@CuCo2O4 polyaniline), achieved highly stable direct analysis perspiration, without...
Herein we synthesized a new Pd–N-heterocyclic carbene (Pd-NHC) complex which featured an acenaphthoimidazolylidene (AnIm) skeleton and 2-phenyl-2-oxazoline. This catalyst exhibited extremely high efficiency in Suzuki–Miyaura couplings between N-acyl-glutarimides organoboronic...