Olga A. Goryacheva

ORCID: 0000-0002-0910-7694
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Quantum Dots Synthesis And Properties
  • Carbon and Quantum Dots Applications
  • Nanocluster Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Biosensors and Analytical Detection
  • Mycotoxins in Agriculture and Food
  • Nanoparticle-Based Drug Delivery
  • Chalcogenide Semiconductor Thin Films
  • Luminescence and Fluorescent Materials
  • Enterobacteriaceae and Cronobacter Research
  • Advanced Biosensing Techniques and Applications
  • MicroRNA in disease regulation
  • Electrochemical sensors and biosensors
  • Catalytic Processes in Materials Science
  • Nanoplatforms for cancer theranostics
  • RNA Interference and Gene Delivery
  • Dendrimers and Hyperbranched Polymers
  • Bone Tissue Engineering Materials
  • Muscle and Compartmental Disorders
  • Inorganic and Organometallic Chemistry
  • Ultrasound and Hyperthermia Applications
  • Luminescence Properties of Advanced Materials
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Photoacoustic and Ultrasonic Imaging

Saratov State University
2016-2025

Ghent University
2019-2020

A critical point for the successful development of a fluorescent quantum dot (QD)-based immunoassay is maintaining high fluorescence yield QDs during hydrophilization and bioconjugation. In this paper, we carefully designed CdSe/CdS CdSe/CdS/ZnS core–shell heterostructures extended them with silica coating different surface composition allowing preservation as 70% in aqueous media. The silanized containing epoxy carboxy groups were bioconjugated monoclonal antibodies. synthesized conjugates...

10.1021/acsami.0c05099 article EN ACS Applied Materials & Interfaces 2020-05-06

Abstract Hollow core microstructured optical fibers (HC‐MOFs) have attracted considerable attention in photonics, particularly for their potential sensing applications biology and medicine. This work presents a novel approach to modifying HC‐MOF inner walls using quantum dots (QDs) facets via hybrid membranes. These modifications are achieved through layer‐by‐layer (LbL) assembly, resulting reduced light transmission spectral red shift. Subsequent annealing restores induces blue A similar...

10.1002/andp.202400147 article EN Annalen der Physik 2025-02-13

Doxorubicin (DOX) is widely used in chemotherapy as an anti-tumor drug. However, DOX highly cardio-, neuro- and cytotoxic. For this reason, the continuous monitoring of concentrations biofluids tissues important. Most methods for determination are complex costly, designed to determine pure DOX. The purpose work demonstrate capabilities analytical nanosensors based on quenching fluorescence alloyed CdZnSeS/ZnS quantum dots (QDs) operative detection. To maximize nanosensor efficiency, spectral...

10.3390/bios13060596 article EN cc-by Biosensors 2023-05-31

This paper describes the step-by-step development and application of a lateral flow immunoassay (LFIA) for detection N-terminal pro-brain natriuretic peptide (NT-proBNP). NT-proBNP is widely used as biomarker diagnosing heart failure other cardiac dysfunctions, distinguishing patients with from without failure, risk assessment. CdSe/CdS fluorescent quantum dots (QDs) were synthesized labels, carefully coated silicon dioxide shell high fluorescence yield 51% silanized QDs, finally...

10.1016/j.talo.2023.100186 article EN cc-by Talanta Open 2023-01-22

Fluorophore-modified cerium oxide nanoparticles (CeO 2 NPs), which have powerful antioxidant properties and high fluorescence intensity, are promising nanomaterials for the treatment of diseases associated with oxidative stress.

10.1039/d4cp00237g article EN Physical Chemistry Chemical Physics 2024-01-01

Abstract Luminescent quantum dots (QDs) of I–III–VI 2 semiconductors present a new class luminescence materials that combine unique optical and electronic properties while exhibiting low toxicity compared to conventional cadmium-based QDs. Advances in the colloidal synthesis ternary QDs have been used develop fluorescence chemical biological sensors for detection various analytes. The review covers main approaches synthesizing structure, features their structure properties, current trends...

10.1134/s1061934822040086 article EN cc-by Journal of Analytical Chemistry 2022-04-01

Complex immunosuppressive therapy is prescribed in medical practice to patients with glomerulonephritis help them overcome symptoms and prevent chronic renal failure. Such an approach requires long-term systemic administration of strong medications, which causes severe side effects. This work shows the efficiency polymer capsule accumulation (2.8 ± 0.4 µm) containing labeled etanercept (100 μg per dose) kidneys mice. The comparison injection into artery tail vein significant superiority...

10.3390/ijms24032784 article EN International Journal of Molecular Sciences 2023-02-01

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10.2139/ssrn.4797874 preprint EN 2024-01-01
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