A5108008865- Invertebrate Immune Response Mechanisms
- Renal Transplantation Outcomes and Treatments
- Aquaculture disease management and microbiota
- Pregnancy and Medication Impact
- Protein Hydrolysis and Bioactive Peptides
- Blood Pressure and Hypertension Studies
- Transplantation: Methods and Outcomes
- Prostate Cancer Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Radiation Dose and Imaging
- Wound Healing and Treatments
- Vascular Malformations Diagnosis and Treatment
- Psychosomatic Disorders and Their Treatments
- Inflammasome and immune disorders
- Crystallization and Solubility Studies
- Medical Imaging Techniques and Applications
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Ferroptosis and cancer prognosis
- Silk-based biomaterials and applications
- Aquatic life and conservation
- Liver Disease and Transplantation
Freie Universität Berlin
2024-2025
Charité - Universitätsmedizin Berlin
2024-2025
Humboldt-Universität zu Berlin
2024-2025
Indiana University – Purdue University Indianapolis
2024
Indiana University School of Medicine
2024
Food Research Institute
2011-2014
Technical University of Denmark
2013
Wake Forest University
2009
Chirurgische Universitätsklinik Heidelberg
2004-2005
Heidelberg University
2004-2005
Abstract Purpose The objective of this study was to evaluate the perioperative outcomes and complications associated with use acetylsalicylic acid (ASA) in deceased donor kidney transplantation (KTX), a particular focus on bleeding events. Methods We retrospectively analyzed 157 transplant recipients (KTRs) who underwent KTX at Charité Berlin, Department for Urology, between February 2014 December 2017. Patients were divided into two groups: patients ASA their preoperative medication (Group...
Abstract STING is a key element in the cGAS/STING cytosolic DNA sensing pathway which can stimulate immune response through type I interferon (IFN) production. Numerous agonists are currently evaluated for their suitability as anticancer drugs. Most previous studies focused on expression inflammatory cells, but also be expressed cancer cells. To evaluate potential clinical significance of bladder was analyzed by immunohistochemistry more than 2,500 urothelial carcinomas tissue microarray...
Niels Lassen’s seminal 1959 cerebral autoregulation plot, a cornerstone in understanding the relationship between mean arterial pressure (MAP) and blood flow (CBF), was based on preexisting literature. However, this work has faced criticism for selective data presentation, leading to inaccurate interpretation. This review revisits validates original plot using contemporary published since 2000. Additionally, we aim understand impact of vasoactive drug treatments CBF, as referenced studies...
Abstract Purpose Accurate surgical reconstruction of arterial vascular supply is a crucial part living kidney transplantation (LDKT). The presence multiple renal arteries (MRA) in grafts can be challenging. In the present study, we investigated impact ligation versus anastomosis small accessory graft on perioperative outcome. Methods Clinical and radiological outcomes 51 patients with MRA out total 308 who underwent LDKT between 2011 2020 were stratified two groups analyzed. group 1 (20...
(Departments of Radiology, Neurology, and Anesthesiology, Medical College Wisconsin, Milwaukee County Complex, Milwaukee, Wisconsin).
Kidney transplant recipients (KTRs) have an increased risk of developing genitourinary cancers, including prostate cancer (PCa), which is expected to become more prevalent due aging KTR population. Thus, knowledge surgical outcomes, treatment PCa, within this unique cohort required.
Abstract Background IgA nephropathy (IgAN) is a common primary glomerulonephritis leading to end-stage renal disease. Living donor kidney transplantation (LDKT) considered favorable treatment option, but IgAN recurrence rates and the impact on outcome unclear. In present study, we retrospectively analyzed rate of recurrence, risk factors clinical outcomes in LDKT recipients. Methods We 193 adult patients who received between 2011 2017 which 32 (16.7%) had as underlying Demographic data...
<h3>Background</h3> Tertiary Lymphoid Structures (TLS) are aggregates of immune cells that form at sites chronic inflammation. Presence tumor-associated TLS has recently been shown to associate with checkpoint inhibitor response independent known biomarkers. This makes induction a promising mechanism for novel immunotherapy target discovery. However, the gold standard detection method by pathologists is both time and labor intensive, limiting biology research scale. Recent advances in AI...
<h3>Background</h3> While the field has made significant advances in understanding cancer-immunity cycle and defining patient 'immunotypes', predicting clinical success for a therapeutic given population remains an unsolved problem. Meanwhile, of artificial intelligence (AI) have aided design molecules to drug known targets, but not helped identify novel targets their appropriate populations. Furthermore, recent technological enabled high-resolution, multiplexed spatial profiling cells,...
Partial cystectomy (PC) has been proposed as a less invasive alternative to radical (RC) for the treatment of localized muscle-invasive bladder cancer (MIBC). The aim this study was evaluate outcome PC in contemporary patient cohort identify potential risk factors procedure.
Twenty-three patients [mean age 49.7 ± 5.6 years (WHO II-III)] with severe hypertension and not responding to previous drug treatment were included in the study evaluate effect of nitrendipine (NTP) as monotherapy also combination propranolol (PRO). After a control period 10 days. NTP was started 20 mg twice day titrated maximal dosage 2 × 40 mg/day. 1 week treatment, PRO added increasing 100 lowered systolic diastolic blood pressure (BP) significantly (supine BP from 182/119 19/9 157/98...