A5049402105- Action Observation and Synchronization
- Motor Control and Adaptation
- Memory and Neural Mechanisms
- Sleep and Wakefulness Research
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Multisensory perception and integration
- Sleep and related disorders
- Pain Mechanisms and Treatments
- Advanced Neuroimaging Techniques and Applications
- Regulation of Appetite and Obesity
- Stress Responses and Cortisol
- Eating Disorders and Behaviors
- Hemispheric Asymmetry in Neuroscience
- Language, Metaphor, and Cognition
- Tactile and Sensory Interactions
- Pain Management and Placebo Effect
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Visual perception and processing mechanisms
- Traumatic Brain Injury Research
- Olfactory and Sensory Function Studies
- Cardiovascular Syncope and Autonomic Disorders
- Child and Animal Learning Development
- Human-Automation Interaction and Safety
University Medical Center Hamburg-Eppendorf
2011-2021
Universität Hamburg
2011-2021
Max Planck Society
2010
Max Planck Institute for Human Cognitive and Brain Sciences
2006-2010
University of Lübeck
2008-2009
University Hospital Schleswig-Holstein
2008-2009
Landesamt für Umwelt, Naturschutz und Geologie
2008
Objective: Adolescents are particularly vulnerable to addiction, and in the case of smoking, this often leads long-lasting nicotine dependence. The authors investigated a possible neural mechanism underlying vulnerability. Method: Functional MRI was performed during reward anticipation 43 adolescent smokers subjects matched on age, gender, IQ. also assessed group differences novelty seeking, impulsivity, delay discounting. Results: In relation comparison subjects, showed greater discounting...
The cognitive and neural representation of abstract words is still an open question for theories embodied cognition. Generally, it proposed that are grounded in the activation sensorimotor or at least experiential properties, exactly as concrete words. Further behavioral propose multiple representations evoked by We conducted a functional magnetic resonance imaging (fMRI) study to investigate correlates multi-word expressions action context. Participants were required read simple sentences...
The aim of the current study was to identify typical alterations in resting state connectivity within different stages migraine cycle and thus explore task-free mechanisms headache attack generation migraineurs.Recent evidence pathophysiology suggests that hours even days before certain changes brain activity take place, ultimately leading an attack. Here, we investigate onset using functional magnetic resonance imaging (fMRI).Nine episodic migraineurs underwent daily for a minimum period 30...
Sleep has a profound impact on memory consolidation. In this study, human participants underwent Pavlovian conditioning and extinction before we manipulated nocturnal consolidation by split-night protocol with 80 healthy male in four groups. Recall after second (recovery) night of sleep revealed that sleeping the first half night, which is dominated slow-wave sleep, did not improve recall. Conversely, rapid eye movement (REM) led to better discrimination between fear-relevant neutral stimuli...
Sleep loss is associated with increased obesity risk, as demonstrated by correlations between sleep duration and change in body mass index or fat percentage. Whereas previous studies linked this weight gain to disturbed endocrine parameters after deprivation restriction, neuroimaging revealed upregulated neural processing of food rewards reward-processing areas such the anterior cingulate cortex, ventral striatum, insula. To address ongoing debate hormonal versus hedonic factors underlying...
Sleep deprivation (SD) has detrimental effects on cognition, but the affected psychological processes and underlying neural mechanisms are still essentially unclear. Here we combined functional magnetic resonance imaging computational modeling to examine how SD alters representation of specific choice variables (subjective value decision conflict) during reward-related making. Twenty-two human subjects underwent two neuroimaging sessions in counterbalanced order, once rested wakefulness...
Object manipulation produces characteristic sounds and causes specific haptic sensations that facilitate the recognition of manipulated object. To identify neural correlates audio-haptic binding object features, healthy volunteers underwent functional magnetic resonance imaging while they matched a target to sample within across audition touch. By introducing delay between presentation stimuli, it was possible dissociate haptic-to-auditory auditory-to-haptic matching. We hypothesized only...
The efficacy of current treatments for anxiety disorders is limited by high relapse rates. Relapse and addiction can be triggered exposure to life adversity, but the underlying mechanisms remain unexplored. Seventy-six healthy adults were a priori selected presence or absence adverse experiences during childhood (CA) recent past (RA; that is, 12 months). Participants underwent fear conditioning (day 1) extinction experimental return-of-fear (ROF) induction through reinstatement (a model...
Abstract The investigation of imitation, which consists observation and later reproduction voluntary actions, promises insights into the complex processes human actions. Although several aspects concerning component neural necessary for action execution are known, our current understanding networks underlying these remains sparse. present study applies independent analysis (ICA) to functional magnetic resonance imaging (fMRI) data acquired during imitation abstract gestures object‐related...
Attentional interference between tasks performed in parallel is known to have strong and often undesired effects. As yet, however, the mechanisms by which operates remain elusive. A better knowledge of these processes may facilitate our understanding effects attention on human performance debilitating consequences that disruptions can have. According load theory cognitive control, processing task-irrelevant stimuli increased attending a relevant task with high demands. This due engaging...
Abstract The ability to maintain information for a short period of time (i.e. working memory, WM) tends decrease across the life span with large inter-individual variability; underlying neuronal bases, however, remain unclear. To address this issue, we used multimodal imaging approach (voxel-based morphometry, diffusion-tensor imaging, electroencephalography) test contribution brain structures and neural oscillations in an elderly population. Thirty-one healthy participants performed...
A motor component is pre-requisite to any communicative act as one must inherently move communicate. To learn make a act, the brain be able dynamically associate arbitrary percepts neural substrate underlying activity. We aimed investigate whether regions involved in complex gestures (ventral pre-motor cortex, Brodmann Area 44) were mediating association between novel abstract auditory stimuli and gestural movements. In functional resonance imaging (fMRI) study we asked participants...
Abstract Dopaminergic brain structures like the nucleus accumbens (NAc) are thought to encode incentive salience of palatable foods motivating appetitive behaviour. Animal studies have identified neural networks mediating regulation hedonic feeding that comprise connections NAc with ventral tegmental area (VTA) and lateral hypothalamus (LH). Here, we investigated how structural connectivity these pathways relates individual variability in decisions on sweet food consumption humans. We...