A5012538292- Spinal Fractures and Fixation Techniques
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Bone fractures and treatments
- Spine and Intervertebral Disc Pathology
- Orthopedic Infections and Treatments
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Pregnancy-related medical research
- Shoulder Injury and Treatment
- Trauma Management and Diagnosis
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Bone Tissue Engineering Materials
- Scoliosis diagnosis and treatment
- Musculoskeletal pain and rehabilitation
- Muscle and Compartmental Disorders
- Infectious Diseases and Tuberculosis
- Infective Endocarditis Diagnosis and Management
- Hernia repair and management
- Body Contouring and Surgery
- Peptidase Inhibition and Analysis
- Bacterial Identification and Susceptibility Testing
- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
Allegheny General Hospital
2013-2024
Allegheny Health Network
2017-2024
Drexel University
2004-2022
Temple University
2013-2018
Neurological Surgery
2016
University of Pittsburgh
2009-2014
Orthopedic One
2013
Penn State Milton S. Hershey Medical Center
2009
Pennsylvania State University
2009
Vanderbilt University
2007
A recent paradigm shift in microbiology affects orthopaedic surgery and most other medical dental disciplines because more than 65% of bacterial infections treated by clinicians the developed world are now known to be caused organisms growing biofilms. These slime-enclosed communities bacteria inherently resistant host defenses conventional antibacterial therapy, these device-related chronic unaffected vaccines antibiotics that have virtually eliminated acute planktonic (floating) bacteria....
Abstract There is an unmet need for developing a new class of smart medical implants with novel properties and advanced functionalities. Here, the concept “self‐aware implants” proposed to enable creation generation multifunctional metamaterial implantable devices capable responding their environment, empowering themselves, self‐monitoring condition. These functionalities are achieved via integrating nano energy harvesting mechanical design paradigms. Various aspects highlighted by...
To identify the presence of bacterial biofilms in nonunions comparing molecular techniques (multiplex polymerase chain reaction and mass spectrometry, fluorescent situ hybridization) with routine intraoperative cultures.Thirty-four patients were scheduled for surgery enrolled this ongoing prospective study. Intraoperative specimens collected from removed implants, surrounding tissue membrane, local soft followed by standard culture analysis, Ibis's second generation diagnostics (Ibis...
The reason for the described clinical variability of acute compartment syndrome thigh, with high morbidity and mortality in some patients an uncomplicated course others, is not known. To better define spectrum factors determining this rare entity, we did a retrospective multicenter study 28 29 thigh syndromes. leading cause was blunt trauma from motor vehicle accidents (46%) or contusion (39%). Pain passive motion present all who were conscious, followed by paresthesia (60%), paralysis...
The purpose of our study was to correlate radiographic characteristics with rotator cuff tendon injury on magnetic resonance imaging after fractures the proximal humerus. We prospectively obtained 30 patients humerus classifying each fracture radiographically using Neer and AO systems determining displacement greater tuberosity. Twelve (40.0%) had either complete ruptures or avulsions at least one muscles. No abnormality identified in musculature nine (29%). Severity tendons increased...
Percutaneous fixation of an unstable pelvic ring injury is becoming a popular method stabilization. As posterior percutaneous techniques become more common, the possibility iatrogenic complications increases. This case report describes to superior gluteal artery during iliosacral screw insertion and treatment this potentially devastating injury.
Fractures to the thoracolumbar spine (TLS) commonly occur because of major trauma mechanisms. In one series, 4.4% all patients arriving at a Level I center were diagnosed as having TLS fracture. Approximately 19% 50% these fractures in region will be associated with neurologic damage spinal cord. To date there are no randomized studies and only few prospective specifically addressing subject. The Eastern Association for Surgery Trauma organization Practice Management Guidelines committee set...
Acute compartment syndrome of the thigh is an uncommon condition that associated with a high rate morbidity. Because its rarity, limited information available on long-term functional outcome for patients this and factors affect clinical result.Eighteen acute were evaluated at average sixty-two months after treatment. Functional was by means physical examination, isokinetic thigh-muscle testing, validated scores.Long-term deficits present in eight patients, only five had full recovery...
Displaced scapular body fractures most commonly are treated conservatively. However there is conflicting evidence in the literature regarding outcomes owing to retrospective design of studies, different classification systems, and diverse outcome tools.The functional after nonoperative management displaced was assessed by change DASH (Disability Arm, Shoulder Hand) score; (2) radiographic glenopolar angle (GPA); (3) associated extrascapular injuries that may affect were identified.Forty-nine...
Background: Intra-articular tibia fractures are reported to occur in 1% 25% of diaphyseal fractures. The objective this study was create a standard protocol evaluate noncontiguous malleolar associated with distal third tibial using computed tomography (CT). Methods: Sixty-six patients 67 were treated at level one trauma center from December 2005 November 2007. These then evaluated CT assess the ankle joint. There 45 men and 21 women average age 44 years (range 18–69 years). All films...
Clearance of the cervical spine in patients who have sustained trauma remains a contentious issue. Clinical examination alone is sufficient neurologically intact without neck pain. Patients with pain or those altered mental status depressed level consciousness require further radiographic evaluation. However, no consensus exists as to appropriate imaging modality. Some advocate multidetector CT (MDCT) scanning alone, but this has been criticized because MDCT not sensitive detecting...
OBJECTIVE. The purpose of this study was to describe the technique and experience in using CT guidance for percutaneous iliosacral screw placement patients with unstable pelvic fractures.
Biofilms cause chronic infections including those associated with orthopaedic hardware. The only methods that are Food and Drug Administration-approved for detecting identifying bacterial cultures selected DNA-based polymerase chain reaction detect specific pathogens (eg, methicillin-resistant Staphylococcus aureus). New technologies enable the detection identification of all bacteria present in a sample to determine antibiotic sensitivities organisms.A 34-year-old man sustained an open...
P-15 is a 15-amino-acid-long biomimetic peptide widely demonstrated to enhance osteogenesis in vivo. Despite the prevalence of polyether-ether-ketone (PEEK) interbody device manufacturing, growing body evidence suggests it may produce an unfavorable immune response. The purpose this preliminary study was characterize response and new bone growth surrounding PEEK implants with without peptide-based osteobiologic. A bilateral femoral defect model conducted using New Zealand white rabbits....
The authors reviewed the use of chemotherapy and anterior/posterior spinal fusion without instrumentation to treat children with extensive tuberculosis kyphosis. Six underwent anterior posterior fusion. All patients were followed until after maturity, except for 1 child who died pulmonary 4 months surgery thus was excluded from study. Preoperative kyphotic deformity averaged 100 degrees (range, 75 degrees-130 degrees). average age at time 7.5 years 4.7-10 years). Spinal involvement extended...
Background: Preliminary studies have identified known bacterial pathogens in the knees of patients with osteoarthritis (OA) before arthroplasty. Aims: The current study was designed to determine incidence and types bacteria present synovial fluid native knee joints from adult diagnoses septic arthritis OA. Patients Methods: were enrolled between October 2010 January 2013. Synovial samples affected collected evaluated both traditional microbial culture polymerase chain reaction–electrospray...
Halo-vest orthoses have been associated with complications. Previous reports suggested increased complications in elderly patients; however, data are limited. This study reviewed 75 patients =/>65 years cervical spine fractures treated halo-vest orthoses. Forty-one (55%) experienced at least 1 complication. Pin-site problems were the most frequent adverse outcome. Seventeen (23%) had significant pulmonary compromise. Pulmonary high morbidity. We found an 8% early mortality rate. useful...