A5000288155- Psychosomatic Disorders and Their Treatments
- Retinal Development and Disorders
- Electronic Health Records Systems
- Neurobiology and Insect Physiology Research
- Mosquito-borne diseases and control
- Hereditary Neurological Disorders
- RNA regulation and disease
- Clinical Reasoning and Diagnostic Skills
- Complementary and Alternative Medicine Studies
- Hemoglobinopathies and Related Disorders
- Pharmacological Effects and Toxicity Studies
- Blood groups and transfusion
- Zebrafish Biomedical Research Applications
- Cardiac electrophysiology and arrhythmias
- Healthcare Systems and Technology
- Neuroblastoma Research and Treatments
- Medical Research and Practices
- Adolescent and Pediatric Healthcare
- Pediatric Pain Management Techniques
- Infectious Encephalopathies and Encephalitis
- Child Abuse and Related Trauma
- Advances in Oncology and Radiotherapy
- Health Literacy and Information Accessibility
- Hippo pathway signaling and YAP/TAZ
- Neurological diseases and metabolism
Michigan Medicine
2000-2022
Pediatrics and Genetics
2020
University of Michigan
1978-2017
Ann Arbor VA Medical Center
2001-2016
Neurology, Inc
1978-2001
Women's Hospital
1996
Albert Einstein College of Medicine
1991
The Food and Drug Administration licensed a live-virus varicella vaccine (Varivax; Merck & Co Inc, West Point, PA) in March 1995. Prelicensure adverse events were minimal; however, since licensure increased use, rare previously undetected risks have arisen. Presented here is the clinical course of undiagnosed, human immunodeficiency virus-infected boy who developed dissemination strain zoster after immunization. chickenpox, virus, pneumonia, encephalopathy, vaccine, events, dissemination.
ABSTRACT Adult goldfish had one tectal lobe removed surgically, and several months later, the eye contralateral to missing tectum was injected with radioactive proline. Radioautographs of brains were studied trace paths termination sites optic fibers. The tract decussated at chiasm, as normally, but then ran caudally in a large neuroma on tectum-less side brain. Substantial numbers fibers left this enter two or more five commissures, through which they recrossed midline. These commissures:...
In January 2019, a new plant-derived purified cannabidiol preparation, approved by the US Food and Drug Administration, became commercially available for patients ≥2 years old with Lennox-Gastaut syndrome or Dravet syndrome. Among our who were prescribed formulation, we observed several cases of thrombocytopenia therefore embarked on this study. We conducted single-center systematic chart review all pediatric (<21 old) from to August 2019. evaluated salient features patients' epilepsy...
Somatization, or physical symptoms that are inconsistent with a physiological cause may not involve an identified stressor, is common in outpatient pediatrics. When these persist, they can impair function and progress to somatic symptom related disorder (SSRD), resulting increased health care use demands on primary providers (PCPs). We performed needs assessment among PCPs better understand how best support caring for children SSRDs. Pediatric (n = 77) were surveyed their training,...
Strokes and their sequelae are a known complication of sickle cell disease [1], yet far less is about the neurological complications rarer hemoglobinopathies. In this report, case stroke moyamoya described in child with hemoglobin (Hb) Casper, rare unstable mutation.A 9-year-old right-handed girl history hemolytic anemia, status post-splenectomy, previously identified right frontal encephalomalacia presented 1-month episodic upper extremity weakness 'garbled' speech.Her examination was...
OBJECTIVES: The diagnostic category of somatic symptom and related disorders (SSRDs), although common, is often poorly recognized suboptimally managed in inpatient pediatric care. Little literature exists to address SSRDs the setting. purpose study was characterize current SSRD practice, identify problem areas workflow, develop a standardized approach evaluation management at tertiary care academic children’s hospital. METHODS: A multidisciplinary group identified patients with admitted...
Low-molecular-weight heparins, such as enoxaparin, are often used to treat thrombosis in infants. We present 4 infants with diffuse brain injury who developed cerebral venous sinus or deep vein and were treated enoxaparin. These subsequently subdural hemorrhages, enoxaparin was stopped. In 3 cases, the hemorrhages found on routine surveillance MRI, 1 case imaging urgently obtained because of focal seizures. Two patients needed urgent neurosurgical intervention, all improved resolved...
The purpose of this study was to evaluate the added utility gadolinium administration in magnetic resonance imaging (MRI) workup seizures children younger than 2 years. A computerized retrospective search radiology information system identified all brain MRI examinations performed at authors' institution from 1995 2002 for Review clinical records revealed that 437 a total 1466 on subset pediatric population were as part an initial seizure workup. Magnetic reports and notes reviewed. studies...
Abstract Afferents often form synapses on restricted regions of their target cells. The connections between vestibular axons and the Mauthner cell are an example this sort specificity. cells a pair identifiable central neurons in certain fish amphibians. In axolotl ( Ambystoma mexicanum ), large club endings only one portion dendrite cell. During development, specific distribution might result from nothing more than when where growing meet (spatiotemporal model). Alternatively, reflect...
This review discusses two clinically important topics concerning assessment and prevention of nervous system malformations. It also summarizes some recent advances in developmental biology that are likely to be significant the future. Modern imaging techniques have allowed better categorization neural migratory defects, aiding our ability prognosticate cases, surgically treat such defects. One major controversy regarding nutritional supplementation tube defects has been resolved, but debate...
Abstract Vestibular axons form synapses on a restricted area of the lateral dendrite Mauthner cell, large, identified brainstem neuron found in fish land amphibians. The differentiation vestibular nerve, medullary neuropil, and cell axolotl ( Ambystoma mexicanum ) was studied to understand better means by which this synaptic specificity arises. first extends medial process then dendrite. latter initially elongates as simple later sends out branches. As grows, enter one earliest several...
The standard physical examination evaluation for a proprioception abnormality depends upon the patient's ability to follow directions and respond examiner, skill not yet developed in toddlers. This study demonstrates new method that may allow better localization of lesions determines whether healthy toddlers would cooperate with this test. By placing stickers on children's hands, covering their eyes, then moving examiner can see children reach where hands were previously located or location,...