A5038150650- Circular RNAs in diseases
- Gestational Diabetes Research and Management
- Signaling Pathways in Disease
- Receptor Mechanisms and Signaling
- T-cell and B-cell Immunology
- Cardiovascular Issues in Pregnancy
- Pregnancy and preeclampsia studies
- MicroRNA in disease regulation
- Monoclonal and Polyclonal Antibodies Research
Universidade de São Paulo
2023-2025
Universidade Federal de Mato Grosso
2024
Actin-associated proteins have been implicated in several stages of virus infection. However, the role myosins, which are actin-dependent molecular motors, during infection and pathogenesis is poorly understood. Myosin IXB (Myo9b) a member myosin family abundantly expressed immune cells. Myo9b displays RhoGTPase-activating protein domain capable modulating actin dynamics by inhibiting RhoGTPase activity. To enquire upon participation infections, we silenced U937 Jurkat cells infected them...
Acute ST-elevation myocardial infarction (STEMI) can lead to adverse cardiac remodeling, resulting in left ventricular systolic dysfunction (LVSd) and heart failure. Epigenetic regulators, such as microRNAs, may be involved the physiopathology of LVSd.This study explored microRNAs peripheral blood mononuclear cells (PBMC) post-myocardial patients with LVSd.Post-STEMI were grouped having (LVSd, n = 9) or not LVSd (non-LVSd, 16). The expression 61 was analyzed PBMC by RT-qPCR differentially...
Excess weight during pregnancy is a condition that can affect both mother and fetus, through the maternal-fetal interface, which constituted by placenta umbilical cord. The vein responsible for transporting oxygen nutrients to its proper functioning depends on integrity of structure. remodeling represents one causes inadequate transport being potentially harmful. This study aims evaluate whether maternal overweight alters structural characteristics vein.