A5007586215- Cardiac Arrest and Resuscitation
- Neonatal and Maternal Infections
- Inflammasome and immune disorders
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Streptococcal Infections and Treatments
University of Copenhagen
2017
Rigshospitalet
2017
Abstract Early assessment of necrotising soft tissue infection (NSTI) is challenging. Analysis inflammatory markers could provide important information about disease severity and guide decision making. For this purpose, we investigated the association between cytokine levels Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC)-score, mortality in NSTI patients. In 159 patients, plasma was analysed IL-1β, IL-6, IL-10 TNF-α upon admission. The assessed by SAPS, SOFA score, septic...
Septic shock remains a leading cause of death worldwide. Hyperbaric oxygen treatment (HBO2) has been shown to alter the inflammatory response during sepsis and reduce mortality. A therapeutic window HBO2 demonstrated experimentally, but optimal timing uncertain. We investigated effects 24 h delayed normobaric (NBO2) on endogenous production markers interleukin (IL)-6, tumor necrosis factor (TNF)-α IL-10, mortality in rats with cecal ligation puncture (CLP) induced sepsis.Fifty-five male...