A5030540130- Cancer Cells and Metastasis
- Clinical practice guidelines implementation
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory mediators and NSAID effects
- Fibroblast Growth Factor Research
- Genomics and Rare Diseases
- Meta-analysis and systematic reviews
- Healthcare Quality and Management
- Biomedical Text Mining and Ontologies
- Metabolism and Genetic Disorders
- Mechanisms of cancer metastasis
- Cancer Research and Treatments
- Clinical Reasoning and Diagnostic Skills
- S100 Proteins and Annexins
- Digestive system and related health
- Metastasis and carcinoma case studies
- Clinical Laboratory Practices and Quality Control
- Barrier Structure and Function Studies
Centre Hospitalier Universitaire de Liège
2021-2023
University of Liège
2010-2021
Centre Hospitalier Universitaire de Reims
2011
Institute of Molecular and Cell Biology
2011
Université de Reims Champagne-Ardenne
2011
Inserm
2011
Rapid Whole Genome Sequencing (rWGS) represents a valuable exploration in critically ill pediatric patients. Early diagnosis allows care to be adjusted. We evaluated the feasibility, turnaround time (TAT), yield, and utility of rWGS Belgium. Twenty-one unrelated patients were recruited from neonatal intensive units, unit, neuropediatric offered as first tier test. Libraries prepared laboratory human genetics University Liège using Illumina DNA PCR-free protocol. was performed on NovaSeq 6000...
Accumulating data now suggest that ZO-1, once delocalized from tight junctions, could be implicated in the regulation of tumor-promoting genes. Because their major implication different steps tumor progression, we investigated here influence ZO-1 on chemokines expression breast cancer cells. Using GeneArray analysis to compare chemokine mRNA cells transfected with a siRNA against identified CXCL-8IL-8 as potential target signaling, being strongly downregulated following transfection....
Errors in laboratory medicine could compromise patient safety. Good practice includes identifying and managing nonconformities the total test process. Varying error percentages have been described other fields but are lacking for molecular oncology.To gain insight into incident causes frequency process from 8 European institutes routinely performing biomarker tests non-small cell lung cancer colorectal cancer.All incidents documented 2018 were collected all hospital services...
Background Participation in quality controls, also called external assessment (EQA) schemes, is required for the ISO15189 accreditation of Medical Centers Human Genetics. However, directives on minimal frequency participation genetic control schemes are lacking or too heterogeneous, with a possible impact health care quality. Objective The aim this project to develop Belgian guidelines controls testing context rare diseases. Methods A group experts analyzed 90 EQA offered by accredited...
<sec> <title>BACKGROUND</title> Participation in quality controls, also called external assessment (EQA) schemes, is required for the ISO15189 accreditation of Medical Centers Human Genetics. However, directives on minimal frequency participation genetic control schemes are lacking or too heterogeneous, with a possible impact health care quality. </sec> <title>OBJECTIVE</title> The aim this project to develop Belgian guidelines controls testing context rare diseases. <title>METHODS</title> A...