A5059132586- Ion-surface interactions and analysis
- Mass Spectrometry Techniques and Applications
- Analytical chemistry methods development
- Electron and X-Ray Spectroscopy Techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Diamond and Carbon-based Materials Research
- Integrated Circuits and Semiconductor Failure Analysis
- Nuclear Physics and Applications
- Metabolomics and Mass Spectrometry Studies
- Advancements in Photolithography Techniques
- Forensic Fingerprint Detection Methods
- Spectroscopy Techniques in Biomedical and Chemical Research
- Semiconductor materials and devices
- Analytical Chemistry and Chromatography
- Advanced Materials Characterization Techniques
- Advancements in Battery Materials
- Bacterial biofilms and quorum sensing
- Isotope Analysis in Ecology
- Luminescence and Fluorescent Materials
- Bacterial Identification and Susceptibility Testing
- Bioinformatics and Genomic Networks
- Advanced Battery Materials and Technologies
- Advanced Chemical Sensor Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Graphene research and applications
National Physical Laboratory
2016-2025
University of Liverpool
2025
Samsung (South Korea)
2022
Teddington Memorial Hospital
2015-2021
University of Nottingham
2011-2020
ORCID
2020
Swansea University
2017-2018
Pacific Northwest National Laboratory
2018
Age UK
2017
GlaxoSmithKline (United Kingdom)
2017
We determine the effect of defects induced by ion bombardment on Raman spectrum single-layer molybdenum disulfide. The evolution both linewidths and frequency shifts first-order bands with density is explained a phonon confinement model, using functional theory to calculate dispersion curves. identify several defect-induced scattering peaks arising from zone-edge modes. Among these, most prominent $\mathrm{LA}(M)$ peak at...
Abstract Viral infections are a serious health challenge, and the COVID-19 pandemic has increased demand for antiviral measures treatments clean surfaces, especially in public places. Here, we review range of natural synthetic surface materials coatings with properties, including metals, polymers biopolymers, graphene antimicrobial peptides, their underpinning mechanisms. We also discuss physico-chemical properties surfaces which influence virus attachment persistence on surfaces. Finally,...
Artificial sweeteners are used as calorie-free sugar substitutes in many food products and their consumption has increased substantially over the past years
Abstract The in‐depth understanding of the composition‐property‐performance relationship solid electrolyte interphase (SEI) is basis developing a reliable SEI to stablize Zn anode‐electrolyte interface, but it remains unclear in rechargeable aqueous zinc ion batteries. Herein, well‐designed based on 2 M Zn(CF 3 SO ) ‐0.2 acrylamide‐0.2 ZnSO 4 proposed. A robust polymer (polyacrylamide)‐inorganic (Zn (OH) 6 .xH O) hybrid situ constructed anodes through controllable polymerization acrylamide...
The binding energies of the calibration peaks for x-ray photoelectron spectroscopy—Cu 2p3/2, Ag 3d5/2 and Au 4f7/2—have been reassessed based on traceable data recorded in 1984 using unmonochromated x-rays an analyser resolution 0.3 eV. changes those energies, different sources resolutions, have calculated results compared with further data. This includes work monochromatic Al at high energy resolution, allowing to be referred a new zero value set Fermi edge measured Ag. A consistent is...
Cluster ion beams have revolutionized the analysis of organic surfaces in time-of-flight secondary mass spectrometry and opened up new capabilities for depth profiling. Much effort has been devoted to understanding improving performance SF(5)(+) C(60)(n+), which are successful many, but not all, materials. Here, we explore potential profiling using novel argon cluster ions, Ar(500)(+) Ar(1000)(+). We present results an delta layer reference sample, consisting ultrathin "delta" layers Irganox...
Detecting metabolites and parent compound within a cell type is now priority for pharmaceutical development. In this context, three-dimensional secondary ion mass spectrometry (SIMS) imaging was used to investigate the cellular uptake of antiarrhythmic agent amiodarone, phospholipidosis-inducing compound. The high lateral resolution 3D capabilities SIMS combined with multiplex ToF spectrometric detection allows visualization in single cells. intact, unlabeled drug successfully detected at...
The depth profiling of organic materials with argon cluster ion sputtering has recently become widely available several manufacturers surface analytical instrumentation producing sources suitable for analysis. In this work, we assess the performance in an interlaboratory study under auspices VAMAS (Versailles Project on Advanced Materials and Standards). results are compared to a previous that focused C60q+ using similar reference materials. Four laboratories participated time-of-flight...
The concept of asymmetric electronic conductance is explored in solid-state batteries and realised by a p–n junction interphase, enabling dynamic dendrite-free operation via slow reductive generation rapid oxidative elimination.
Abstract The in‐depth understanding of the composition‐property‐performance relationship solid electrolyte interphase (SEI) is basis developing a reliable SEI to stablize Zn anode‐electrolyte interface, but it remains unclear in rechargeable aqueous zinc ion batteries. Herein, well‐designed based on 2 M Zn(CF 3 SO ) ‐0.2 acrylamide‐0.2 ZnSO 4 proposed. A robust polymer (polyacrylamide)‐inorganic (Zn (OH) 6 .xH O) hybrid situ constructed anodes through controllable polymerization acrylamide...
Understanding tumor heterogeneity is a major challenge that was recognized as one of the first Cancer Grand Challenges, with call to provide solutions visualize heterogeneity. The Rosetta team took on this challenge, exploiting advances in spatial-omics approaches centered around mass spectrometry imaging map at cellular and molecular scales different levels resolution. See related article by Bressan et al., p. 16 Stratton 22 Bhattacharjee 28.
Abstract Sputter‐depth profiles of model organic thin films on silicon using C 60 primary ions have been employed to measure sputtering yields and depth resolution parameters. We demonstrate that some materials (polylactide, Irganox 1010) a constant high yield, which varies linearly with the ion energy, whereas another material (Alq 3 ) has lower, fluence‐dependent yields. Analysis multi‐layered reveals is function both energy depth, yield depends history sputtering. also show ∼30% repeat...
Abstract An analysis has been made of the historical data for argon ion sputtering yields 28 mono‐elemental solids in energy range 250–10 000 eV to develop an improved semi‐empirical formula based on Matsunami et al. 's and Yamamura Tawara's formulations. The best result is found if essential component involving target density included approach. scatter between predictions experimental reduced 9.0% by generating analytical expression term Q that requires none target‐specific numbers from...
Alternating layers of two different organic materials, Irganox1010 and Irganox3114, have been created using vapor deposition. The Irganox3114 were very thin (∼2.5 nm) in comparison to the (∼55 or ∼90 create an equivalent inorganic 'delta-layers' commonly employed as reference materials dynamic secondary ion mass spectrometry. Both identical sputtering yields, we show that delta may be used determine some important metrological parameters for cluster beam depth profiling. We demonstrate, a...
Abstract Ambient mass spectrometry (ambient MS) is a powerful and rapidly growing new field that provides high sensitivity MS directly from surfaces at ambient pressure. There now rich evidence base in the published literature of success these methods for forensic analysis including: detection explosives nanogram levels; chemical composition counterfeit pharmaceutical tablets, drugs abuse biological liquids such as urine plasma; breath metabolites; imaging document verification fingerprint...
Argon cluster ion sources for sputtering and secondary mass spectrometry use projectiles consisting of several hundreds atoms, accelerated to 10-20 keV, deposit their kinetic energy within the top few nanometers surface. For organic materials, yield is high removing material similar depth. Consequently, exposed new surface relatively damage free. It has thus been demonstrated on model samples that it now really possible perform dual beam depth profiling experiments in materials with this...
The quantitative determination of the lattice disorder present in graphene layers will be crucial if this 2-D material is to commercialized. Raman spectroscopy has been shown a powerful technique for characterizing density these defects layers. Here, we study evolution spectra with defect size, vacancy created via ion bombardment. was used analyze variation D-peak and G-peak intensity ratio single-layer graphene, whilst equivalent highly ordered pyrolytic graphite were characterized using...
Secondary ion mass spectrometry(SIMS) has become a powerful technique for the label-free analysis of organics from cells to electronic devices. The development cluster sources revolutionized field, increasing sensitivity by two or three orders magnitude and large clusters, such as C60 argon allowing depth profiling organics. latter provided capability generate stunning dimensional images with resolutions around 5 nm, simply unavailable other techniques. Current state-of-the-art allows...