A5037991587- Soil and Water Nutrient Dynamics
- Fish Ecology and Management Studies
- Intracranial Aneurysms: Treatment and Complications
- Dental Education, Practice, Research
- Water Quality and Pollution Assessment
- Hydrology and Watershed Management Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Urban Stormwater Management Solutions
- Freshwater macroinvertebrate diversity and ecology
- Molecular Sensors and Ion Detection
- Aquatic Ecosystems and Phytoplankton Dynamics
- Marine and coastal ecosystems
- Pharmaceutical and Antibiotic Environmental Impacts
- Hydrology and Sediment Transport Processes
- Analytical Chemistry and Sensors
- Lanthanide and Transition Metal Complexes
- Constructed Wetlands for Wastewater Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Wastewater Treatment and Nitrogen Removal
- Analytical chemistry methods development
- Helicobacter pylori-related gastroenterology studies
- Flood Risk Assessment and Management
- Inflammatory Bowel Disease
- Acute Ischemic Stroke Management
Monash University
2016-2025
Western University
2023-2025
University of Bamenda
2025
Apollo Hospitals
2025
Australian and New Zealand Intensive Care Society
2019-2021
Clayton Foundation
2017-2020
Australian Regenerative Medicine Institute
2003-2020
Jacobs (United States)
2020
Macquarie University
2014-2019
University of Alberta
1994-2018
Measurements were made at eight predetermined positions on 627 sets of angiograms from 293 patients with aneurysms. A ratio between the sum vessel diameters in subarachnoid space to base skull and neck was calculated plotted against time. Vasospasm has its onset man about Day 3 after hemorrhage, is maximal Days 6 8, gone by 12. There a tendency for poor clinical grades have more vasospasm. The most vasospasm significantly higher mortality than those least.
✓ A multicenter, randomized placebo-controlled double-blind trial of nimodipine in poor-grade aneurysm patients was carried out 17 Canadian hospitals. Of 188 enrolled the trial, 32 were excluded for protocol violations and two due to statistical considerations, leaving 154 valid outcome analysis. Nimodipine treatment associated with a significantly better (p < 0.001): 21 (29.2%) 72 nimodipine-treated had good at 3 months after subarachnoid hemorrhage (SAH) compared eight (9.8%) 82...
A multitude of biologically active pharmaceuticals contaminate surface waters globally, yet their presence in aquatic food webs remain largely unknown. Here, we show that over 60 pharmaceutical compounds can be detected invertebrates and riparian spiders six streams near Melbourne, Australia. Similar concentrations invertebrate larvae predators suggest direct trophic transfer via emerging adult insects to consume them. As representative vertebrate feeding on invertebrates, platypus brown...
An experiment in >1000 river and riparian sites found spatial patterns controls of carbon processing at the global scale.
The authors have developed a method to induce chronic cerebral vasospasm after subarachnoid hemorrhage (SAH) in monkeys. With microsurgical techniques, 33 monkeys had frontotemporal craniectomy and unilateral opening of the cisterns. Cerebrospinal fluid was drained fresh hematoma, obtained from an average 7 ml autologous blood, carefully placed against major arteries anterior circulation on one side. 30 studied for 14 days SAH were allocated randomly two treatment groups 15: group received...
Pharmaceuticals and personal care products (PPCPs) are ubiquitous in freshwater ecosystems worldwide recognized as contaminants of concern. Currently, concern classified for their persistence, bioaccumulation, toxicity (PBT criteria). PPCPs not persistent organic pollutants (POPs), although some share characteristics similar to POPs. For example, known be pseudopersistent due constant discharge into the environment, often at low concentrations. At commonly reported environmental...
The long-term efficacy of stormwater treatment systems requires continuous pollutant removal without substantial re-release. Hence, the division incoming pollutants between temporary and permanent pathways is fundamental. This pertinent to nitrogen, a critical water body pollutant, which on broad level may be assimilated by plants or microbes temporarily stored, transformed bacteria gaseous forms permanently lost via denitrification. Biofiltration have demonstrated effective nitrogen from...
Abstract The measurement of stream metabolism (gross primary production and respiration) has become more feasible with the availability reliable dissolved oxygen (DO) probes. Such metabolic measurements offer important opportunities in fundamental applied research, especially relating responses to human other pressures. accurate determination reaeration coefficient is one challenge for making ecological inferences from DO made over many diel periods (i.e., months or years). We outline three...
✓ The safety and efficacy of the thrombolytic agent tissue-type plasminogen activator (tPA) in elimination subarachnoid clot prevention chronic vasospasm were evaluated a blind randomized placebo-controlled trial. Twenty-four monkeys randomly assigned to one two groups 12. Each group underwent baseline cerebral angiography coagulation analysis followed by right-sided craniectomy experimental hemorrhage (SAH). An Ommaya reservoir was inserted with its catheter placed into space. hours later...
Salinity is a major problem in many regions of Australia, and predicted to get considerably worse over the next 30–50 years. Most effort has focused on terrestrial environment, specifically loss productive agricultural land. Increased salinity can also result unwanted changes aquatic ecosystems rivers, streams particularly wetlands.This paper first reviews importance assessing risks from increases catchment context, then introduces disturbance–response conceptual model assist with...
Resting energy expenditure (EE) is often used as the basis of nutritional support for critically ill patients but whether resting EE representative total daily not known. was measured 24 h in ten mechanically ventilated, critcally (average Acute Physiology and Chronic Health Evaluation II score 23) to determine EE, expended during various ICU activities. Although activities, such weighing patient on a sling-type bed scale, repositioning, chest physiotherapy resulted dramatic increases above...
The effects of pharmaceuticals on aquatic ecosystems are the subject increasing environmental concern. Of particular interest a suite drugs known as selective serotonin reuptake inhibitors (SSRIs), commonly prescribed to treat depression. SSRIs now detected in environment worldwide, but their not well understood. We conducted replicated experiments testing for an ecosystem effect streams. used artificial stream mesocosms expose natural biofilms and insect communities concentrations (20 µg/L)...
Rivers and streams contribute to global carbon cycling by decomposing immense quantities of terrestrial plant matter. However, decomposition rates are highly variable large-scale patterns drivers this process remain poorly understood. Using a cellulose-based assay reflect the primary constituent detritus, we generated predictive model (81% variance explained) for cellulose across 514 globally distributed streams. A large number variables were important predicting decomposition, highlighting...
✓ The efficacy of complete clot removal 24 hours after subarachnoid hemorrhage (SAH) in the prevention chronic cerebral vasospasm was evaluated monkeys a blind randomized controlled trial. Twenty-four were to one three groups undergo sham-operation (sham-operated group), placement only (clot or and (clot-removal group). By means standard microsurgical techniques, major vessels bilaterally dissected free arachnoid. An autologous hematoma averaging 5 gm placed around spaces clot-removal...
The efficacy of U74006F in the prophylaxis chronic cerebral vasospasm (VSP) was evaluated a randomized, double-blind, placebo-controlled trial. Forty cynomolgus monkeys were divided by restricted randomization into 2 treatment groups 20. Five animals from each group randomized subgroups 1 and 2. subgroup studied pathologically. Brain biopsies performed with high-performance liquid chromatography (HPLC). remaining 20 supplemented number angiographically. Significant VSP (P < 0.05) detected...
Creightons Creek, a rural stream in southeastern Australia, has been severely degraded by large-scale sedimentation of sand the streambed. Our paper highlights use whole-stream metabolism measurements, fluorescein diacetate hydrolysis studies, and situ enzyme mapping to examine effect sediment instability on benthic hyporheic across seasonal flow variations Creek. Median gross primary production (GPP) ecosystem respiration (ER24) rates, determined over 20-mo period with single-station...