A5005869229- Tracheal and airway disorders
- Neonatal Respiratory Health Research
- Pulmonary Hypertension Research and Treatments
- Medical Imaging and Pathology Studies
- Cystic Fibrosis Research Advances
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Vascular Anomalies and Treatments
- Pneumonia and Respiratory Infections
- Asthma and respiratory diseases
- Lipid metabolism and disorders
- Respiratory and Cough-Related Research
- RNA modifications and cancer
- IgG4-Related and Inflammatory Diseases
- Viral-associated cancers and disorders
- IL-33, ST2, and ILC Pathways
- Immune Cell Function and Interaction
- Eosinophilic Disorders and Syndromes
- Venous Thromboembolism Diagnosis and Management
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Congenital Diaphragmatic Hernia Studies
- Respiratory viral infections research
- Antifungal resistance and susceptibility
- Dysphagia Assessment and Management
- Peptidase Inhibition and Analysis
Tongji University
2014-2024
Shanghai Pulmonary Hospital
2014-2024
Background: Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by abnormal surfactant accumulation. In recent years, transbronchial cryo-biopsy (TBCB) has gradually been applied as it can obtain larger and better-quality specimens. This study aims to assess the diagnostic yield safety of TBCB in PAP. Methods: included 78 PAP patients who underwent lung biopsy. Thirty-six them biopsy (TBLB) with forceps other 42 TBCB. Clinical data, specimen number size, pathologic lesion...
Abstract Introduction The characteristics of Allergic Bronchopulmonary Aspergillosis (ABPA) based on its radiological classification is still unclear. Objectives To investigate the clinical significances ABPA patients with central bronchiectasis (ABPA‐CB) by different classifications mucus plugs. Methods ABPA‐CB from a pulmonary hospital between 2008 and 2015 were retrospectively included analysed. According to chest imaging in their first visit physician, divided into two groups presence...
Abstract Introduction Lung damage related to tuberculosis is a major contributor the etiology of bronchiectasis in China. It unknown whether severity score systems are applicable these cases. Objectives To evaluate clinical characteristics and validation for post‐tuberculosis bronchiectasis. Methods The study enrolled 596 patients Shanghai Pulmonary Hospital between January 2011 December 2012. data calculating FACED index (BSI) scores along with mortality, readmission, exacerbation outcomes...
The major causes of pulmonary infections are various microorganisms. This study aimed to compare the positive rates pathogenic microorganism DNA/RNA high-throughput genetic sequencing (PMseq), which is an emerging technique, with traditional methods for disease detection, and investigate differences in different sample types.Bronchoalveolar lavage fluid (BALF) venous blood samples from 104 patients were collected detection.The PMseq BALF both significantly higher than those same (P<0.001)....
Castleman's disease (CD) is a rare that most commonly occurs in the mediastinum. The lung site which CD may occur. current study reported 2 cases of localized lungs. Computed tomography imaging identified high-density mass lungs two patients. Biopsy and pathological examinations indicated one case presented features types (hyaline-vascular plasma cell types), while other suffered from multicentric CD. present highlighted typical clinical In addition, it proposed diagnosis should be...
Abstract Background Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by abnormal surfactant accumulation. The small tissue specimens obtained transbronchial lung biopsy (TBLB) could not adequately meet the need for subsequent diagnosis. In recent years, cryo-biopsy (TBCB) has gradually been applied as it can obtain larger and better-quality specimens. This study aims to assess diagnostic yield safety of TBCB in PAP. Methods subjects this retrospective are 78 PAP patients...
Objective To explore the inflammatory mechanisms of pulmonary embolism (PTE) and/or deep venous thrombosis (DVT) in elders secondary to chronic obstructive disease (COPD) exacerbation. Methods A total 26 with acute exacerbation high-risk COPD PTE DVT and patients low-risk during stable phase diagnosed period January 2008 December 2012 were enrolled. The relevant parameters routine blood examination, viscosity, D-dimer, fibrinogen (FIB), arterial gas, cytokine, erythrocyte...
Abstract Background: Tracheobronchomalacia (TBM) is an infrequent airway disease, but frequently unrecognized or misdiagnosed with other respiratory diseases, and its etiology remains unclear in China. Methods: Anthropometric information, smoking history, medical symptoms, signs, etiology, diagnosis, treatment prognosis of ten patients were retrospectively analyzed. Etiologies summarized from previous reports Western countries. Results: The median onset age the was 55 years. Patients...
Abstract Background: Serum lactate dehydrogenase (LDH), carcinoembryonic antigen (CEA) and CYFRA21-1 are the commonly used biomarkers to identify patients with autoimmune pulmonary alveolar proteinosis (APAP). However, it is not clear which of more sensitive severity patient’s condition. Methods: APAP numbering 151 were enrolled in this study. All patients’ was assessed through prognosis score PAP (SPSP). According respective laboratory upper limits serum levels LDH, CEA CYFRA21-1, divided...