- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Streptococcal Infections and Treatments
- Herpesvirus Infections and Treatments
- Rabies epidemiology and control
- Medical Imaging and Pathology Studies
- Cerebrospinal fluid and hydrocephalus
- Veterinary Oncology Research
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Head and Neck Surgical Oncology
- Poxvirus research and outbreaks
- Viral Infections and Outbreaks Research
- Particle Dynamics in Fluid Flows
- Protein Degradation and Inhibitors
- Nail Diseases and Treatments
- Bacterial Infections and Vaccines
- RNA regulation and disease
- Psychoanalysis and Psychopathology Research
- T-cell and B-cell Immunology
- Aquaculture disease management and microbiota
- interferon and immune responses
- Bone health and treatments
- Actinomycetales infections and treatment
- Bacterial Identification and Susceptibility Testing
University of Veterinary Medicine Hannover, Foundation
2020-2024
University of Veterinary Medicine
2023
Abstract Glaesserella parasuis is an important pathogen in swine production. It acts as a primary systemic Glässer´s disease and secondary Porcine Respiratory Disease Complex. In this study, collection of 308 isolates from carrier animals individuals with respiratory or isolated 2012–2019 Germany was analysed. Isolates were characterized for serovar implementing two different PCR methods. Additionally, methods pathotyping applied to the results compared. Serovar 6 ( p < 0.0001) 9 (p =...
Histologic diagnosis of less well-differentiated cases canine extramedullary plasmacytomas (CEMPs) may require immunohistochemical confirmation to discriminate these tumors from other round cells including lymphoma, cutaneous histiocytoma, and amelanotic melanomas. CEMPs are characterized by widespread immunoreactivity for multiple myeloma 1 (MUM1) antigen λ light chains, while the melanocytic marker melan-A has been reported yield negative results. Here, 33 randomly selected CEMPs, 20...
Abstract Serotyping is the most common method to characterize field isolates of Actinobacillus (A.) pleuropneumoniae , etiological agent porcine pleuropneumonia. Based on serology, many farms seem be infected and antibodies against a wide variety serovars are detectable, but, so far it unknown what degree respective contribute outbreaks clinical manifest disease. In this study, 213 German A. retrieved for diagnostic purposes from pleuropneumonia between 2010 2019 were genetically serotyped...
Rift Valley fever (RVF) is a zoonotic and emerging disease, caused by the RVF virus (RVFV). In ruminants, it leads to “abortion storms” enhanced mortality rates in young animals, whereas humans can cause symptoms like severe hemorrhagic or encephalitis. The role of innate adaptive immune response disease initiation progression still poorly defined. present study used attenuated RVFV strain clone 13 investigate viral spread, tissue tropism, histopathological lesions after intranasal infection...
Einleitung Der Krallenfrosch stellt ein vielgenutztes Tiermodell für die biomedizinische Forschung dar. Jedoch sind Informationen über altersassoziierte Erscheinungen und Neoplasien dieser Spezies kaum vorhanden.
Abstract Meningoencephalitis of unknown origin is mostly considered a disease young small dogs and terrier breeds, while older presenting with clinical signs deteriorating encephalopathy are more commonly diagnosed intracranial neoplasia. In this case series, three Australian shepherd dogs, 7, 10 11 years old, were meningoencephalitis origin; serial magnetic resonance imaging in two postmortem examination one dog. Follow‐up after 4 months showed complete resolution abnormalities dog treated...
Einleitung Fibro-ossäre Neoplasien stellen benigne Tumoren dar, die aus variablen Anteilen von Binde- und Knochengewebe bestehen. Hierbei muss zwischen Osteomen, ossifizierenden Fibromen fibrösen Dysplasien unterschieden werden.
Introduction Canine extramedullary plasmacytomas (cEMPs) are usually benign neoplasms characterized by immunoreactivity with the plasmacytic marker MUM1. Immunostaining for Melan-A, a cells of melanocytic and neuroendocrine origin, is not reported in cEMPs.
Einleitung Lupus erythematodes ist eine bei Menschen, Hunden, Katzen und Pferden beschriebene Autoimmunerkrankung, der zwischen systemischen kutanen Formen differenziert wird. Die Krankheit äußert sich oft durch faziale Dermatitis. Sie wird verursacht Ausbildung von antinukleären anti-DNS Autoantikörpern.
Einleitung Arachnoidalzysten stellen seltene, angeborene oder erworbene, flüssigkeitsgefüllte Strukturen der Meningen des Gehirns Rückenmarks dar. Intrakranielle sind typischerweise im Bereich Lamina quadrigemina lokalisiert und müssen als Umfangsvermehrungen von Neoplasien differenziert werden.
Einleitung Eine Infektion mit dem Rifttalfieber-Virus (RVFV) kann beim Menschen zu einer schweren Enzephalitis führen. Die IFN-I-Antwort (IFN-I = Typ-I-Interferon) spielt eine zentrale Rolle in der Virusabwehr, die Bedeutung einzelnen Zellpopulationen im zentralen Nervensystem (ZNS) für Pathogenese ist bisher jedoch nicht Detail geklärt.