- Antioxidant Activity and Oxidative Stress
- Free Radicals and Antioxidants
- Redox biology and oxidative stress
- Sulfur Compounds in Biology
- Selenium in Biological Systems
- Vitamin C and Antioxidants Research
- Nitric Oxide and Endothelin Effects
- Glutathione Transferases and Polymorphisms
- Organoselenium and organotellurium chemistry
- Skin Protection and Aging
- Metabolism and Genetic Disorders
- Retinoids in leukemia and cellular processes
- bioluminescence and chemiluminescence research
- Photodynamic Therapy Research Studies
- Genomics, phytochemicals, and oxidative stress
- Phytochemicals and Antioxidant Activities
- Pharmacogenetics and Drug Metabolism
- Trace Elements in Health
- Eicosanoids and Hypertension Pharmacology
- Drug Transport and Resistance Mechanisms
- Connexins and lens biology
- Mitochondrial Function and Pathology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Electron Spin Resonance Studies
- Biochemical effects in animals
Heinrich Heine University Düsseldorf
2015-2024
Leibniz Institute of Environmental Medicine
2014-2024
University of Lübeck
1989-2023
Goethe University Frankfurt
2023
Massachusetts General Hospital
2023
Immundiagnostik (Germany)
2023
Brunel University of London
2022
Hochschule Düsseldorf University of Applied Sciences
1993-2021
Institute of Molecular Biology
2016-2018
Düsseldorf University Hospital
2003-2016
Abstract As a normal attribute of aerobic life, structural damage to organic compounds wide variety (DNA, proteins, carbohydrates and lipids) may occur as consequence oxidative reactions. Oxidative inflicted by reactive oxygen species has been called “oxidative stress”. Biological systems contain powerful enzymatic nonenzymatic antioxidant systems, stress denotes shift in the prooxidant/antioxidant balance favor former. Diverse biological processes such inflammation, carcinogenesis, ageing,...
Epidemiological and medical anthropological investigations suggest that flavanol-rich foods exert cardiovascular health benefits. Endothelial dysfunction, a prognostically relevant key event in atherosclerosis, is characterized by decreased bioactivity of nitric oxide (NO) impaired flow-mediated vasodilation (FMD). We show healthy male adults the ingestion cocoa was associated with acute elevations levels circulating NO species, an enhanced FMD response conduit arteries, augmented...