Helmut Sies

ORCID: 0000-0002-1000-3198
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About
Contact & Profiles
Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Free Radicals and Antioxidants
  • Redox biology and oxidative stress
  • Sulfur Compounds in Biology
  • Selenium in Biological Systems
  • Vitamin C and Antioxidants Research
  • Nitric Oxide and Endothelin Effects
  • Glutathione Transferases and Polymorphisms
  • Organoselenium and organotellurium chemistry
  • Skin Protection and Aging
  • Metabolism and Genetic Disorders
  • Retinoids in leukemia and cellular processes
  • bioluminescence and chemiluminescence research
  • Photodynamic Therapy Research Studies
  • Genomics, phytochemicals, and oxidative stress
  • Phytochemicals and Antioxidant Activities
  • Pharmacogenetics and Drug Metabolism
  • Trace Elements in Health
  • Eicosanoids and Hypertension Pharmacology
  • Drug Transport and Resistance Mechanisms
  • Connexins and lens biology
  • Mitochondrial Function and Pathology
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Electron Spin Resonance Studies
  • Biochemical effects in animals

Heinrich Heine University Düsseldorf
2015-2024

Leibniz Institute of Environmental Medicine
2014-2024

University of Lübeck
1989-2023

Goethe University Frankfurt
2023

Massachusetts General Hospital
2023

Immundiagnostik (Germany)
2023

Brunel University of London
2022

Hochschule Düsseldorf University of Applied Sciences
1993-2021

Institute of Molecular Biology
2016-2018

Düsseldorf University Hospital
2003-2016

10.1152/physrev.1979.59.3.527 article Physiological Reviews 1979-07-01

Abstract As a normal attribute of aerobic life, structural damage to organic compounds wide variety (DNA, proteins, carbohydrates and lipids) may occur as consequence oxidative reactions. Oxidative inflicted by reactive oxygen species has been called “oxidative stress”. Biological systems contain powerful enzymatic nonenzymatic antioxidant systems, stress denotes shift in the prooxidant/antioxidant balance favor former. Diverse biological processes such inflammation, carcinogenesis, ageing,...

10.1002/anie.198610581 article EN Angewandte Chemie International Edition 1986-12-01

Epidemiological and medical anthropological investigations suggest that flavanol-rich foods exert cardiovascular health benefits. Endothelial dysfunction, a prognostically relevant key event in atherosclerosis, is characterized by decreased bioactivity of nitric oxide (NO) impaired flow-mediated vasodilation (FMD). We show healthy male adults the ingestion cocoa was associated with acute elevations levels circulating NO species, an enhanced FMD response conduit arteries, augmented...

10.1073/pnas.0510168103 article EN Proceedings of the National Academy of Sciences 2006-01-17

10.1093/ajcn/66.1.116 article EN publisher-specific-oa American Journal of Clinical Nutrition 1997-07-01
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