A5100637816- Geotechnical Engineering and Analysis
- Geotechnical Engineering and Underground Structures
- Innovative concrete reinforcement materials
- Civil and Geotechnical Engineering Research
- Structural Behavior of Reinforced Concrete
- Grouting, Rheology, and Soil Mechanics
- Geotechnical Engineering and Soil Stabilization
- Geomechanics and Mining Engineering
- Rock Mechanics and Modeling
- Concrete and Cement Materials Research
- Soil, Finite Element Methods
- Landslides and related hazards
- Geotechnical and Geomechanical Engineering
- Tunneling and Rock Mechanics
- Structural Load-Bearing Analysis
- Advanced Sensor and Control Systems
- Drilling and Well Engineering
- Numerical methods in engineering
- Advanced Computational Techniques and Applications
- Circular RNAs in diseases
- Geotechnical Engineering and Soil Mechanics
- Concrete Corrosion and Durability
- Geoscience and Mining Technology
- Safety and Risk Management
- Concrete Properties and Behavior
Central South University
2014-2025
Nanjing Forestry University
2015-2024
Zhejiang University
2024
Southeast University
2005-2022
Guangxi University
2019-2021
Southwest Jiaotong University
2019-2021
Chongqing University
2006-2021
Ministry of Transport
2020-2021
Changsha University of Science and Technology
2016-2020
Nagoya University
2014-2017
Abstract Background Emerging evidence suggest the critical role of circular RNAs (circRNAs) in disease development especially various cancers. However, oncogenic circRNAs hepatocellular carcinoma (HCC) is still largely unknown. Methods RNA sequencing was performed to identify significantly upregulated paired HCC tissues and non-tumor tissues. CCK-8 assay, colony formation, transwell, xenograft mouse models were used investigate proliferation metastasis. Small interfering (siRNA) silence gene...
COVID-19 is mainly associated with respiratory distress syndrome, but a subset of patients often present gastrointestinal (GI) symptoms. Imbalances gut microbiota have been previously linked to virus infection. Understanding how the gut-lung axis affects progression can provide novel framework for therapies and management. In this study, we examined (n = 47) compared it healthy controls 19). Using shotgun metagenomic sequencing, identified four microorganisms unique in patients, namely...
A general and facile catalytic asymmetric protocol for the construction of enantioenriched spiro gem-diamines through [3+3] annulation α,β-unsaturated N-sulfonyl ketimines 3-aminobenzofurans has been accomplished under catalysis of...
A case of damages in the secondary lining a multiarch tunnel is studied by field investigation and numerical analysis, which subject to asymmetry pressure buried at shallow depth. The study focuses on key influencing factors inducing these damages. analysis implemented, taking account possible obtained from investigation, two cases with different models are utilized discriminate effects caused depth asymmetric comparatively. result demonstrates that topography has much influence safety...
The excavation of a deep foundation pit adjacent to an existing tunnel may lead the large deformation and induce damages in structure. However, influence on structure from nearby excavations has not been understood clearly, since it is affected by complex influencing factors only geological topographical conditions but also construction method positional relationship structures. This paper presents numerical investigation into underground rail transit line during pit, which behavior...
This paper presents a case study of damage in the concrete lining an operational tunnel by field investigation and numerical analysis, which field-investigated construction deficiency is considered model, implemented analysis adopted for investigating effect damaging structure operating induced deficiency. The illustrates that cavity can influence stress state plays important role stability tunnel, results significant on must be timely treated to prevent subsequent lining. Moreover, model...
This paper presents a systematical numerical investigation into the lining performance of tunnel with cavities around surrounding rocks, focusing on influences cavity size and multicavity distribution. The study demonstrates that rocks have much influence stability may induce damages in structures, which width has more severe effect stress state structures than depth. Moreover, also illustrates nonadjacent distribution multicavities serious from adjacent as well single cavity.
Grouting materials require not only high ultra-early-stage strength of the stone body, but also proper working performances, such as fluidity and fast setting time, well good stability. Compared with traditional pure cement grout, geopolymer grouting material has advantages fluidity, slurry stability, early which is beneficial to reuse solid waste resources can be applied conditions rapid construction or repair work a certain extent. This paper presents an experimental investigation into...
Within the past 2 decades, three highly pathogenic human coronaviruses have emerged, namely, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East (MERS-CoV), and (SARS-CoV-2). The health threats economic burden posed by these tremendously paved way for research on their etiology, pathogenesis, treatment. Compared to SARS-CoV SARS-CoV-2, MERS-CoV genome encoded fewer accessory proteins, among which ORF4b protein had anti-immunity ability in both cytoplasm nucleus. Our work...
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