A5088513419- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Graphene and Nanomaterials Applications
- Hydrogels: synthesis, properties, applications
- Curcumin's Biomedical Applications
- 2D Materials and Applications
- 3D Printing in Biomedical Research
- Carbon and Quantum Dots Applications
- Dendrimers and Hyperbranched Polymers
- Advancements in Transdermal Drug Delivery
- Microbial Metabolic Engineering and Bioproduction
- MXene and MAX Phase Materials
- Advanced Photocatalysis Techniques
- Cellular Mechanics and Interactions
- Nanocluster Synthesis and Applications
- Supramolecular Self-Assembly in Materials
- Advanced Cellulose Research Studies
- Advanced Nanomaterials in Catalysis
- Enzyme Catalysis and Immobilization
- Lipid Membrane Structure and Behavior
- Pluripotent Stem Cells Research
- Molecular Sensors and Ion Detection
- Nanoplatforms for cancer theranostics
- Protein Interaction Studies and Fluorescence Analysis
University of California, Irvine
2023-2024
University of Tehran
2020-2023
Curcumin application as an anti-cancer drug is faced with several impediments. This study has developed a platform that facilitates the sustained release of curcumin, improves loading efficiency, and activity. Montmorillonite (MMT) nanoparticles were added to chitosan (CS)-agarose (Aga) hydrogel then loaded curcumin (Cur) prepare curcumin-loaded nanocomposite hydrogel. The capacity increased from 63% 76% by adding MMT chitosan-agarose Loading fabricated in nanoniosomal emulsion resulted...
Alchemical free energy methods are useful in computer-aided drug design and computational protein because they provide rigorous statistical mechanics-based estimates of differences from molecular dynamics simulations. λ is a method with the ability to characterize combinatorial chemical spaces spanning thousands related systems within single simulation, which gives it distinct advantage over other alchemical that mostly limited pairwise comparisons. Recently developed have improved...
Cancer has been one of the leading causes death worldwide. Chemotherapy is a proposed therapeutic in recent years; however, its efficiency restricted due to multiple drug resistance (MDR), toxicity on normal cells, and poor physicochemical properties. The use natural compounds with less cytotoxicity cells promising approach cancer treatment. Curcumin (CUR) plant flavonol from flavonoid group polyphenols anti-tumor activity. Nonetheless, low solubility, permeability, short biological...
Introduction: With the development of hydrogels from half a century ago, their application in various medical fields, including drug delivery has been widely expanded. Hydrogels used this field are produced with synthetic polymers such as polyvinylpyrrolidone, polyvinyl alcohol, or natural like chitosan, agarose, and hyaluronic acid to develop biocompatible, biodegradable, non-immunogenic carriers. However, limitations inadequate response stimulation, low homogeneity, poor loading capacity...