A5077131330- Pesticide Exposure and Toxicity
- Nanoparticle-Based Drug Delivery
- Pancreatic function and diabetes
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Cholinesterase and Neurodegenerative Diseases
- Curcumin's Biomedical Applications
- Hydrogels: synthesis, properties, applications
- Bone Tissue Engineering Materials
- Heavy Metal Exposure and Toxicity
- Wound Healing and Treatments
- Advanced Nanomaterials in Catalysis
- Carbon and Quantum Dots Applications
- Selenium in Biological Systems
- Environmental Toxicology and Ecotoxicology
- Nanoplatforms for cancer theranostics
- Electrochemical sensors and biosensors
- Diabetes Management and Research
- 3D Printing in Biomedical Research
- Biochemical Acid Research Studies
- Poisoning and overdose treatments
- Coenzyme Q10 studies and effects
- Birth, Development, and Health
- Telomeres, Telomerase, and Senescence
- Diabetes and associated disorders
Tehran University of Medical Sciences
2016-2025
University of Tehran
2012-2023
Pharmaceutical Sciences Research Center
2017-2022
Islamic Azad University Pharmaceutical Sciences Branch
2020-2022
Tissue Dynamics (Israel)
2016
Breast cancer refers to a very common deadly class of malignant tumors, especially in women worldwide. In the present study, promising methodology has been developed simultaneously improve drug loading performance and achieve sustained release 5-fluorouracil (5-FU) as model for breast cancer. For this purpose, pH-sensitive biocompatible hydrogel chitosan/agarose/graphene oxide (CS/AG/GO) was first synthesized with glyoxal cross-linker. 5-FU-loaded nanocomposites (NCs) CS/AG/GO were then...
The COD/Si NP/SF composite, PVA–COD/Si nanofiber, and BC-COD/Si composite were synthesized for wound healing application.
Curcumin application as an anti-cancer drug is faced with several impediments. This study has developed a platform that facilitates the sustained release of curcumin, improves loading efficiency, and activity. Montmorillonite (MMT) nanoparticles were added to chitosan (CS)-agarose (Aga) hydrogel then loaded curcumin (Cur) prepare curcumin-loaded nanocomposite hydrogel. The capacity increased from 63% 76% by adding MMT chitosan-agarose Loading fabricated in nanoniosomal emulsion resulted...
Today, cancer treatment is an important issue in the medical world due to challenges and side effects of ongoing procedures. Current methods can be replaced with targeted nano-drug delivery systems overcome such effects. In present work, intelligent nano-system consisting Chitosan (Ch)/Gamma alumina (γAl)/Fe3O4 5-Fluorouracil (5-FU) was synthesized designed for first time order influence Michigan Cancer Foundation-7 (MCF-7) cell line breast cancer. Physico-chemical characterization...
Type I diabetes mellitus is a metabolic disease caused by the impairment of pancreatic β-cells mainly mediated through oxidative stress and related apoptosis. Islets transplantation seems promising treatment for these patients, but during islets transplant, various types stresses to isolation procedure compromise function viability islets. We recently hypothesized that combination cerium oxide (CeO 2 ) yttrium (Y O 3 nanoparticles with potential free radical scavenger behavior should be...
Silk fibroin (SF), extracted from Bombyx mori, has unique physicochemical properties to achieve an efficient wound dressing. In this study, reduced graphene oxide (RGO)/ZnO NPs/silk nanocomposite was made, and innovative nanofiber of SF/polyvinyl alcohol (PVA)/RGO/ZnO NPs ready with the electrospinning technique successfully characterized. The results MIC OD analyses were used investigate synthesized materials' antibacterial effects displayed that materials could inhibit growth against...
Insulin Dependent Diabetes Mellitus (IDDM) is a disease with high incidence no pure cure therapy yet. In most of cases, these patients need pancreatic islets transplantation that not completely successful because oxidative stress happening during isolation and procedures. the present study, effective factors in procedure such as viability, insulin secretion, production reactive oxygen molecules (ROM), mitochondrial energy ATP/ADP ratio were examined isolated exposed to sodium selenite...
Abstract Nerve tissue engineering (NTE) is one of the most promising methods to restore central nerve systems in human health care. Three‐dimensional (3D) distribution and growth cells within porous scaffold composed nanofibers are clinical significance for NTE. In this study, an attempt was made develop characterize use fibrin gel endometrial stem (hEnSCs)‐derived neuron‐like simultaneously support cell behavior especially neuron outgrowth. The structural mechanical characteristics were...
Analyzing the chemical composition of different kinds acrylic cement is necessary to understand their properties and suitability for curing bone defects. Conducting various tests can give valuable insight into composition, viscosity, performance characteristics each kind cement, Therefore, our study aimed find safety standards effectiveness these products medical applications. The polymeric characterization was determined by Nuclear Magnetic Resonance (H-NMR) spectroscopy Fourier-transform...
Sodium arsenite (SA), NaAsO2, is among the most hazardous toxicants, and wide use presence of this toxicant leads to a severe environmental threat. Exposure SA associated with many health concerns, such as prevalence cancer diabetes mellitus type 2 (DMT2). Many studies suggest that induces inflammation biochemical impairments through different mechanisms, including increasing oxidative stress altering vital genes anti-inflammatory. Recent on melatonin (MLT), harmless hormone secreted in body...