A5064015312- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Osteoarthritis Treatment and Mechanisms
- Alcohol Consumption and Health Effects
- Complementary and Alternative Medicine Studies
- Knee injuries and reconstruction techniques
- Liver Disease and Transplantation
- COVID-19 Clinical Research Studies
- Colorectal Cancer Screening and Detection
- COVID-19 and healthcare impacts
- Microscopic Colitis
- Gastric Cancer Management and Outcomes
- Transplantation: Methods and Outcomes
- Long-Term Effects of COVID-19
- E-commerce and Technology Innovations
- Lower Extremity Biomechanics and Pathologies
- Pharmacological Effects and Assays
- Blood Pressure and Hypertension Studies
- Pharmacological Effects of Natural Compounds
- Medical Coding and Health Information
- Cardiovascular and exercise physiology
- Healthcare cost, quality, practices
- Clinical Nutrition and Gastroenterology
- Medical and Biological Ozone Research
- Drug-Induced Hepatotoxicity and Protection
Thomas Jefferson University Hospital
2021-2023
Southern Illinois University School of Medicine
2023
Thomas Jefferson University
2022-2023
St George's, University of London
2018-2019
Articular cartilage pathology can result from a spectrum of origins, including trauma, osteochondritis dissecans, avascular necrosis, or degenerative joint disease.To compare the differences in clinical and patient-reported outcomes after autologous chondrocyte implantation (ACI) versus osteochondral allograft transplantation (OCA) patients with focal articular defects without underlying bone loss.Cohort study; Level evidence, 3.A retrospective review identified who underwent ACI OCA between...
Osteochondral allograft (OCA) transplantation is a restorative technique for addressing articular cartilage defects by transferring mature viable chondrocytes with subchondral bone into size-matched lesions. The purpose of this study was to compare differences in clinical and functional outcomes patients treated OCA osteochondral compared isolated chondral pathology.A retrospective review identified who underwent grouped them or pathology. Demographic data, surgical history, lesion...
Non-alcoholic fatty liver disease (NAFLD) is a serious clinicopathological condition that recognized as the most frequent chronic disease, affecting 14–30% of world’s population. The prevalence NAFLD has rapidly grown and correlated with growth in obesity type 2 diabetes, among other factors. often results long-term complications including cardiovascular cirrhosis, fibrosis. This paper provides an updated overview focus on epidemiology, etiology, pathophysiology, screening, complications,...
Abstract International Statistical Classification of Disease and Related Health Problems, 10th Revision codes (ICD‐10) are used to characterize cohort comorbidities. Recent literature does not demonstrate standardized extraction methods. Objective: Compare COVID‐19 manual‐chart‐review ICD‐10‐based comorbidity data; the accuracy different methods extracting ICD‐10‐code‐based comorbidity, including temporal with respect critical time points such as day admission. Design: Retrospective...
COVID-19 has disproportionately affected low-income communities and people of color. Previous studies demonstrated that race/ethnicity socioeconomic status (SES) are not independently correlated with mortality. The purpose our study is to determine the effect SES on 30-day mortality in a diverse, Philadelphian population. This retrospective cohort single-center tertiary care hospital Philadelphia, PA. includes adult patients hospitalized polymerase-chain-reaction-confirmed between March 1,...
Endocarditis from Pseudomonas aeruginosa is a rare cause of endocarditis with most those cases in patients intravenous drug abuse. The MitraClip® relatively new device few incidences the literature. Here we present first reported case pseudomonal non-IV user.
Background Uveitis is the most common extraarticular manifestation in patients with spondyloarthritis. It may be first presentation of The combination effects on vision, systemic disease and side treatment have a significant impact patient’s life. affects all age groups results visual impairment over long duration lifetime. Hence, cost due to uveitis similar eye conditions such as cataract, related macular degeneration glaucoma. Objectives There lack national level data regarding medical...
Introduction: Colorectal adenomas are precursors to colorectal cancer, making their detection and removal crucial for effective cancer prevention. The adenoma rate (ADR) serves as an essential quality metric assess the effectiveness of endoscopists in identifying these lesions during colonoscopy. We previously evaluated whether ADR was equivalent 2 age groups (45-49 vs 50-54) undergoing screening within a large health care system Philadelphia, PA. This study aims compare between...
<b>Background:</b> Accurate evaluation of aortic stiffness and pressure wave reflection may improve cardiovascular risk stratification in chronic obstructive pulmonary disease. However, it is not clear whether systemic haemodynamic changes induced acutely by inhaled salbutamol ipratropium confound these measurements. <b>Aim:</b> To investigate the acute effect on measures (aortic pulse velocity/aPWV) (central augmentation index/cAIx). <b>Methods:</b> 27 healthy normotensive adults aged 19-24...
<b>Background:</b> Cardiovascular disease is common in chronic obstructive pulmonary but little known about its effect on capillary rarefaction, a marker of microvascular function. Both inhaled salbutamol and ipratropium can induce systemic haemodynamic changes acutely potentially confounding measurements rarefaction. <b>Aim:</b> To investigate the acute skin density, rarefaction <b>Methods:</b> 27 healthy normotensive adults 19-24 years were recruited into crossover study receiving 400...
Introduction: Inflammatory bowel disease (IBD) patients are at higher risk of Clostridioides difficileinfection (CDI) and subsequent complications including recurrent CDI (rCDI). While newer treatment guidelines recommend fidaxomicin as first line therapy for CDI, oral vancomycin (OV) is still routinely used line. There no to what dose OV should be in IBD with a episode CDI. In this study, we sought compare rCDI rates treated different doses the also evaluate factors these patients. Methods:...
Introduction: Wide-area transepithelial sampling with computer-assisted 3-dimensional analysis (WATS-3D) is a brush-based technique which has demonstrated improved detection of dysplasia during endoscopic surveillance Barrett's esophagus (BE). We aimed to understand current adoption and opportunities increase the WATS-3D brush for BE screening by assessing practice patterns amongst gastroenterologists at Thomas Jefferson University Hospital (TJUH) affiliate sites. Methods: 38 TJUH varied...
Introduction: Delayed gastric emptying is a known complication of viral infections. The pathophysiology this mechanism and its incidence not well described, though the association widely documented. Anecdotally, at our institution patients are seen in Gastroenterology clinics with symptoms nausea vomiting prior diagnosis COVID-19, but no other risk factors for gastroparesis. We aim to identify prevalence previously infected SARS-CoV-2 who develop gastroparesis help providers anticipate...
Introduction: Infection with SARS-CoV-2 can manifest several gastrointestinal symptoms, specifically diarrhea, nausea, vomiting, bleeding and loss of appetite. In patients requiring hospitalization, especially the critically ill, appetite quickly cause severe malnutrition, hindering body’s ability to recover from illness. Severe disease also results in sequelae including prolonged mechanical ventilation stroke, further limiting enteral nutrition many cases, creates a need for percutaneous...