- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Spaceflight effects on biology
- Machine Learning in Healthcare
- Healthcare cost, quality, practices
- Healthcare Technology and Patient Monitoring
- Geriatric Care and Nursing Homes
- Impact of Light on Environment and Health
- Blood disorders and treatments
- COVID-19 diagnosis using AI
- Sleep and Work-Related Fatigue
- Patient-Provider Communication in Healthcare
- Pericarditis and Cardiac Tamponade
- Childhood Cancer Survivors' Quality of Life
- Patient Satisfaction in Healthcare
- Emergency and Acute Care Studies
- Hospital Admissions and Outcomes
- ECG Monitoring and Analysis
- Health Systems, Economic Evaluations, Quality of Life
- Neutropenia and Cancer Infections
- Nursing Diagnosis and Documentation
- Cardiac electrophysiology and arrhythmias
- Cardiac tumors and thrombi
- Occupational Health and Performance
- Advanced Data Processing Techniques
Mayo Clinic
2019-2023
Thomas Jefferson University
2015-2023
Thomas Jefferson University Hospital
2019-2022
Mayo Clinic in Arizona
2020-2021
Brigham and Women's Hospital
2014-2016
Circadian (United States)
2014-2016
Sleep deficiency and the use of sleep-promoting medication are prevalent during spaceflight. Operations frequently dictate work biological night sleep day, which contribute to circadian misalignment. We investigated whether misalignment was associated with adverse outcomes before (preflight) spaceflight missions aboard International Space Station (ISS). Actigraphy photometry data for 21 astronauts were collected over 3,248 days long-duration on ISS 11 prior launch (n=231 days). logs, one out...
Abstract The basic goal of this research is to determine the best combination light wavelengths for use as a lighting countermeasure circadian and sleep disruption during space exploration, well individuals living on E arth. Action spectra employing monochromatic selected wavelength comparisons have shown that short‐wavelength visible in blue‐appearing portion spectrum most potent neuroendocrine, circadian, neurobehavioral regulation. studies presented here tested hypothesis broad spectrum,...
During the early months of COVID-19 pandemic, mortality associated with disease declined in United States. The standard care for pharmacological interventions evolved during this period as new and repurposed treatments were used alone combination. Though these medications have been studied individually, data are limited regarding relative impact different medication combinations. objectives study to evaluate association COVID-19-related observed combinations determine whether changes...
Mobile electrocardiograms (ECGs) (mECGs) using smartphone applications are an emerging technology.In the coronavirus disease 2019 (COVID-19) era, minimizing patient contact has gained increasing importance.Additionally, increased QT/corrected QT (QTc) monitoring concurrently been required.The KardiaMobile 6L ECG device, cleared by United States Food and Drug Administration (FDA) for recording ECGs, along with KardiaStation tablet application is a platform (AliveCor, Mountain View, CA, USA)...
Abstract International Statistical Classification of Disease and Related Health Problems, 10th Revision codes (ICD‐10) are used to characterize cohort comorbidities. Recent literature does not demonstrate standardized extraction methods. Objective: Compare COVID‐19 manual‐chart‐review ICD‐10‐based comorbidity data; the accuracy different methods extracting ICD‐10‐code‐based comorbidity, including temporal with respect critical time points such as day admission. Design: Retrospective...
Time spent awaiting discharge after the acute need for hospitalization has resolved is an important potential contributor to hospital length of stay (LOS). To measure prevalence, impact, and context patients who remain hospitalized prolonged periods completion care needs. We conducted a cross-sectional "point-in-time" survey at each 15 academic US hospitals using structured data collection tool with on-service medicine attending physicians in fall 2022. Primary outcomes were number...
Coronavirus disease 2019 (COVID-19) carries high morbidity and mortality globally. Identification of patients at risk for clinical deterioration upon presentation would aid in triaging, prognostication, allocation resources experimental treatments.
COVID-19 has disproportionately affected low-income communities and people of color. Previous studies demonstrated that race/ethnicity socioeconomic status (SES) are not independently correlated with mortality. The purpose our study is to determine the effect SES on 30-day mortality in a diverse, Philadelphian population. This retrospective cohort single-center tertiary care hospital Philadelphia, PA. includes adult patients hospitalized polymerase-chain-reaction-confirmed between March 1,...
ABSTRACT Background Coronavirus disease 2019 (COVID-19) carries high morbidity and mortality globally. Identification of patients at risk for clinical deterioration upon presentation would aid in triaging, prognostication, allocation resources experimental treatments. Research Question Can we develop validate a web-based prediction model identification who may severe COVID-19, defined as intensive care unit (ICU) admission, mechanical ventilation, and/or death? Methods This retrospective...
In rare instances, cytopenias manifest as a complication of thyrotoxicosis. Here, we report case Graves disease (GD) thyrotoxicosis presenting pancytopenia that resolved with antithyroid therapy.A 35-year-old male presented fever and chills following an outpatient colonoscopy. Initial blood work revealed pancytopenia. Workup included viral antigen titers, cultures, rheumatologic antibodies, inflammatory markers, immunocompetency, nutrient deficiency, metal toxicity, malignancy. Bone marrow...
Introduction: Gastrointestinal (GI) malignancies are associated with paraneoplastic sequelae such as non-bacterial thrombotic endocarditis (NBTE) and inflammatory myopathy. We describe a unique case in which metastatic gastric malignancy presented without typical GI symptoms instead was discovered after pursuing unifying diagnosis for constellation of cardiac, neurologic, musculoskeletal manifestations. Case Description/Methods: A 61-year-old woman to tertiary medical center shoulder thigh...