Respiratory failure is a life threatening complication of Guillain Barré syndrome (GBS). There no consensus on the specific treatment for this subset children with GBS.This was prospective randomized study to compare outcome intravenous immunoglobulin (IVIG) and plasma exchange (PE) in GBS requiring mechanical ventilation. Forty-one endotracheal ventilation (MV) within 14 days from disease onset were included. The ages ranged 49 143 months.Randomly, 20 received five-day course IVIG (0.4...

Abstract Albuminuria has been considered the golden standard biomarker for diabetic kidney disease (DKD), but appears once significant damage already occurred. Angiopoietin-2 (Angpt-2) implicated in development and progression of DKD adults. We aimed to explore association serum Angpt-2 levels with children adolescents type 1 diabetes mellitus (T1DM) short duration (3–5 years) evaluate predictive power early detection prior microalbuminuric phase. The current cross-sectional study included...

This study retrospectively investigates the indications and results of renal biopsy in children to determine patterns childhood kidney disease a single tertiary children's hospital Egypt. We included all patients who underwent ultrasound-guided from 1998 2012. All biopsies were studied under light microscopy, while immunofluorescence electron microscopy performed when indicated. A total 1246 over 15 years, on 1096 patients. The mean age at time was 9.2 ± 3.7 years. main indication for...

Studies examining sleep patterns in children on hemodialysis (HD) are lacking. This cross-sectional, control-matched group study was performed to assess the quality HD. The assessment made using a subjective and questionnaire objective analysis full night polysomnography. A total of 25 with end-stage renal disease (ESRD) HD were compared 15 age- sex-matched controls. average age cases 14 ± 4 years, 52% males mean body mass index 20 3.8 kg/m². duration dialysis 2.6 2 years. Analysis data...

Early detection of kidney injury in neonates is very important for appropriate management and prevention serious complications; however, commonly used detectors as creatinine blood urea nitrogen (BUN) do not directly reflect early renal cell injury. Serum cystatin-C (Cys-C) beta 2-microglobulin (Β2M), serum BUN were assessed 20 who developed impairment after admission to the neonatal intensive care unit 10 healthy neonates. The means Cys-C, Β2M on Day 1 cases control groups 2.15 ± 0.52 vs...

Interferon-α (IFN-α), a cytokine with both antiviral and immune-regulatory functions, was suggested as useful tool which can evaluate current systemic lupus erythematosus (SLE) disease activity identify patients who are at risk of future flares. In the study, serum IFN-α levels associated demographic, serological features in Egyptian SLE their first degree relatives (FDRs) comparison to unrelated healthy controls (UHCs) were examined, order individuals greatest for clinical illness....

The reno-protective effect of therapeutic hypothermia in infants with hypoxic ischemic encephalopathy (HIE) is still debatable. We aimed to study the on development and progress acute kidney injury (AKI) neonates HIE. Thirty full term HIE were equally distributed between cooling group (selective head cooling) or non-cooling (late presentation after 6 hours birth). Serum creatinine, urine output (UOP), serum neutrophil gelatinase-associated lipocalin (NGAL), cystatin C measured at baseline,...

The purpose of the current study was to investigate chemical composition Moringa seeds, extract oil, and prepare a nanoemulsion using whey proteins, with its properties application as food model in ice cream. Expressed on dry weight , seeds exhibited moisture content 7.20 ± 0.75, whereas contents fiber, ash, fat, total carbohydrate were25.35 0.15 %, 7.95 0.25%, 5.57 0.23%, 44.33 1.09%, 17.85 0.72%, respectively. Oleic acid main fatty (C18:1) 36.63%. Oil-in-water nanoemulsions were prepared...

Schimke immune-osseous dysplasia (SIOD) is a rare autosomal recessive disorder characterized by spondylo-epiphyseal (SED), progressive renal insufficiency beginning as steroid-resistant nephrotic syndrome (SRNS) and defective cellular immunity. This article reports case from Egypt with mild form of SIOD. A 14.5-year-old male patient presented disproportionate short stature, SRNS (focal segmental glomerulosclerosis), laboratory evidence immune deficiency radiologic characteristics SED. He...

People have constantly looked for bioactive compounds that improve health throughout history. The current study investigates the protection of components Moringa oleifera seed oil (MSO) and its use in producing functional ice cream. Four formulations nanoemulsions were prepared by cold gel techniques using sodium caseinate (NaCas) as an emulsifier MSO. 5% NaCas MSO (T1), 10% (T2), (T3), (T4). From results, T1 exhibited lowest particle size (125.80 nm) narrow distribution. In comparison, T4...

Background: According to The Centers for Disease Control and Prevention (CDC) 2019, around 32,000 deaths in addition 2.8 million infections occur annually the US because of antibiotic-resistant bacteria. Objectives: To determine prevalence study pattern antibiotic use resistance among Iraqi patients. Methodology: We carried out a cross-sectional from January 2021 October 2022 including data 850 patients at different private general hospitals, primary health centers, clinics. was collected...

The most common cause of Nephrotic Syndrome (NS) in children is idiopathic NS, also called nephrosis. prominent clinical signs are hyperlipidemia, severe proteinuria, edema, swelling body tissues, and an increased risk infection. object this study was to examine the correlation ABCB1 gene (rs10276036, C > T), IL-18, TNFα prevalence NS among Egyptian having NS.

Hemolytic-uremic syndrome (HUS) is a leading cause of childhood acute kidney injury (AKI) worldwide, with its postdiarrheal (D+HUS) form being the most common. Scarce data are available regarding D+HUS epidemiology from developing countries. This study aims to reveal characterization D+ HUS in Egyptian children. retrospective all children admitted tertiary pediatric hospital Egypt between 2007 and 2017. The included epidemiological, clinical laboratory data; management details; outcomes. A...

Abstract Background This study aimed to describe the prevalence of various clinical features and severity juvenile systemic lupus erythematosus (jSLE) assess predictors AQP4-Ab positivity in jSLE. In addition, we assessed relationship AQP4-Abs with neuropsychiatric disorders white matter lesions Method For 90 patients jSLE, demographic data, manifestations, treatments received were recorded, all underwent examinations, including assessments for neurological manifestations jSLE disorders;...