A5035730464- Nosocomial Infections in ICU
- Respiratory Support and Mechanisms
- Peripheral Neuropathies and Disorders
- Renal function and acid-base balance
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Cancer therapeutics and mechanisms
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Tracheal and airway disorders
- Infant Nutrition and Health
- Potassium and Related Disorders
- Asthma and respiratory diseases
- Circadian rhythm and melatonin
- Coronary Artery Anomalies
- Kawasaki Disease and Coronary Complications
- Long-Term Effects of COVID-19
- Cell death mechanisms and regulation
- Congenital Anomalies and Fetal Surgery
- Congenital Heart Disease Studies
- Pleural and Pulmonary Diseases
- Acute Lymphoblastic Leukemia research
- Congenital heart defects research
- Chronic Kidney Disease and Diabetes
Mansoura University
2007-2024
Children's Hospital Mansoura University
2011-2022
Boston Children's Hospital
2008
Respiratory failure is a life threatening complication of Guillain Barré syndrome (GBS). There no consensus on the specific treatment for this subset children with GBS.This was prospective randomized study to compare outcome intravenous immunoglobulin (IVIG) and plasma exchange (PE) in GBS requiring mechanical ventilation. Forty-one endotracheal ventilation (MV) within 14 days from disease onset were included. The ages ranged 49 143 months.Randomly, 20 received five-day course IVIG (0.4...
Tumor necrosis factor (TNF) alpha-308 and interleukin (IL)-10(-1082) have potent inflammatory responses in the process of airway inflammation asthma. The purpose this study was to check for association polymorphisms related cytokine genes with susceptibility severity bronchial asthma Egyptian children. Blood samples 69 asthmatic children receiving treatment follow-up at Allergy Respiratory Medicine Unit, Mansoura University Children Hospital, Mansoura, Egypt, were subjected DNA extraction...
About 25-50% of multisystem inflammatory syndrome in children (MIS-C) patients meet the criteria for diagnosis Kawasaki disease (KD). The differentiation both conditions is so challenging on clinical practice as management time dependant and precise fundamental.Data were collected from < 18 years old hospitalized with MIS-C or KD. Patient demographics, clinical, laboratory data compared, a discrimination score was created to assist differentiation.72 KD included study. Patients had higher...
Abstract Objective Assessment of the utility lung and diaphragm ultrasound in prediction successful weaning from nasal continuous positive airway pressure (NCPAP) preterm infants. Study Design This prospective cohort study was conducted on infants who were considered ready for off NCPAP. Lung performed just before 3 h after The primary outcome to evaluate accuracy (LUS) predicting Results Out 65 enrolled infants, 30 (46.2%) successfully weaned NCPAP room air. group had higher gestational...
The aim of the study is to characterize markers apoptosis in children with acute lymphoblastic leukemia (ALL) relation treatment outcome disease. was performed on 34 ALL and 39 healthy as a control group. Apoptosis assessed by cell morphology; DNA fragmentation; ELISA RT-PCR for CD95, CD95L, BcL-2 nuclear factor-kappa B (NF-κB); flow cytometry CD40, CD49d CD11a. significantly lower patients than controls. detected CD95 ligand cases no remission after those who achieved remission....
The role of oral hygiene in the intensive care unit is indisputable. Several studies were carried out different pediatric units using regimes. Chlorhexidine preparations are widely used This study was conducted Children's Hospital Mansoura University, Egypt to unravel effect adoption an protocol 0.12% chlorhexidine solution on outcome mechanically ventilated patients. comprised 50 patients admitted period from January 2013 August 2016. sample analyzed as follow: intervention group (28...
Background and aims: Norovirus is one of the leading cause epidemics gastroenteritis worldwide are an important sporadic illnesses in children adults. Aims: The objective was to detect genotype infants younger than 3 years age presenting with acute admitted Mansoura University Children’s Hospital, Egypt. Methods: Eighty six age, over a two period, were prospectively enrolled. Faecal samples collected from within 72 hours onset symptoms for RT-PCR using degenerate primers conserved region....
Abstract Background Congenital heart diseases (CHD) are the commonest congenital anomalies with increased risk in children born from families affected members. However, various recurrence patterns of CHDs have been reported different populations. Therefore, this work aimed to assess a large sample Egyptian families. Methods From January 2020 October 2021, non-syndromic confirmed were recruited. Data collected guardians recruited and hospital records, including index case’s cardiac diagnosis...
Background and aims: Malnutrition is prevalent in developing countries where children with malnutrition constitute a significant proportion of admissions to PICUs. Aims: This study aimed at comparing outcomes PICU admission between well mal-nourished children. Methods: 573 admitted over the period two years tertiary Egypt were prospectively enrolled study. Nutritional assessment was performed using weight, height BMI for age. Children classified into groups; Group A included well-nourished B...
Aims & Objectives: Effect of selective decontamination digestive tract (SDD) and respiratory on the incidence VAP, sepsis, multiple organ dysfunction syndrome (MODS) mortality in PICU. Also we assessed duration mechanical ventilation length stay studied groups. Methods 1. A randomized controlled trial 2. Carried out PICU at Mansoura University Children's Hospital, between January 2014 August 2016. This study included 139 patients, 47 patients were enrolled control group (CG), 46 intervention...
Aims & Objectives: To evaluate acute respiratory distress syndrome (ARDS)-related changes in serum melatonin levels critically ill children PICU. Methods: An observational prospective study carried out PICU at Mansoura University Children’s Hospital, Egypt, from October 2017 to 2018. 28 diagnosed as ARDS with age distribution ranging 1.5 168 months. Patients were recruited consecutively subdivided into two groups; 13 patients criteria of and 15 controls without ARDS. All subjected...
Aims & Objectives: To evaluate the magnitude of metabolic acidosis and number organ dysfunction on survival in children with sepsis PICU. Methods: An observational prospective study carried out PICU at Mansoura University Children’s Hospital, Egypt over period between September 2017 February 2019. This included 80 patients both sexes older than one month, admitted septic shock PH ≤ 7.30. Demographic data were collected. All assessed by PRISM Score III, predicted mortality rate, evaluated for...
Aims & Objectives: To elucidate the prevalence, sensitivity to antibiotics and outcome of Staphylococcus aureus bacteremia in children with sepsis Methods: A prospective cross-sectional study carried out PICU at Mansoura University Children’s Hospital, Egypt from January 2017 December 2018. 97 patients, aged 1 180 months diagnosed as confirmed S. on blood culture were recruited. Demographic data, use mechanical ventilation, inotropes, type vascular access, results cultures, patterns...