A5052977426- Cerebrovascular and Carotid Artery Diseases
- Hemophilia Treatment and Research
- Cardiac Imaging and Diagnostics
- Systemic Lupus Erythematosus Research
- Parathyroid Disorders and Treatments
- Pancreatitis Pathology and Treatment
- Platelet Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Otitis Media and Relapsing Polychondritis
- Inflammatory Bowel Disease
- Liver Diseases and Immunity
- Celiac Disease Research and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Pediatric Urology and Nephrology Studies
- Vitamin D Research Studies
- Cerebral Venous Sinus Thrombosis
- Renal and Vascular Pathologies
- Peripheral Artery Disease Management
- Vasculitis and related conditions
- Sarcoidosis and Beryllium Toxicity Research
- Nutrition and Health in Aging
- Rheumatoid Arthritis Research and Therapies
University of Groningen
2018-2021
University Medical Center Groningen
2016-2020
Center for Vascular Biology Research
2020
18F-NaF positron emission tomography (PET) targets microcalcifications. We compared in vitro microPET assessed uptake between culprit and non-culprit human carotid plaques. Furthermore, we with calcification visualized on microcomputed (microCT). Carotid plaques from stroke patients undergoing surgery were incubated scanned using a microCT scan. The average PET was expressed as percentage of the incubation dose per gram (%Inc/g). volume interest (VOI) CT VOI. 23 (17 culprit, 6 non-culprit)...
Abstract Objectives To compare colour duplex ultrasonography (CDU) findings with axillary 18F-fluorodeoxyglucose (FDG) PET/CT and to the diagnostic performance of temporal artery CDU alone. Methods Patients suspected GCA were retrospectively included. Presence a halo or occlusion was considered positive finding. FDG-PET/CT-assessed involvement defined as FDG uptake higher than liver uptake. The reference clinical diagnosis after 6 months, which based on symptomatology additional tests,...
Systemic presence of arthritis autoantibodies (AAb) is specific for rheumatoid (RA). AAb initiation might be triggered by chronic mucosal inflammation, such as in inflammatory bowel disease (IBD). We assessed the prevalence anti-citrullinated protein antibodies (ACPA) and factor (RF) ulcerative colitis (UC) Crohn’s (CD) patients, with regard to joint complaints AAb+ versus AAb− IBD patients. RA patients healthy subjects (HC) served controls. Serum was collected from 226 UC, 165 CD 86 36 HCs....
<h3>Background</h3> Color duplex ultrasonography (CDU) is recommended as first line of imaging in patients suspected for cranial GCA [1]. However, extra-cranial involvement without temporal artery found up to 40% [2]. CDU very suitable also assess inflammation, which the axillary relatively easy assess. data on value limited [3]. <h3>Objectives</h3> We aimed (1) evaluate performance with by comparing findings [18F]-FDG PET/CT findings. Furthermore, (2) compare sensitivity and specificity...
<h3>Background</h3> Presence of arthritis autoantibodies is specific for rheumatoid (RA). Anti-citrullinated peptide antibodies (ACPA) and factor (RF) can be detected several years before the onset are thought to have a pathogenic role. However, where when autoantibody production starts unclear. A potential trigger could chronic mucosal inflammation as in inflammatory bowel disease (IBD) since gut microbiome involved induction (auto) immunity. This assumption supported by demonstration...