A5052908512- Head and Neck Surgical Oncology
- Pituitary Gland Disorders and Treatments
- Frailty in Older Adults
- Meningioma and schwannoma management
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- Tissue Engineering and Regenerative Medicine
- Sinusitis and nasal conditions
- Oral and Maxillofacial Pathology
- Cellular Mechanics and Interactions
- Salivary Gland Tumors Diagnosis and Treatment
- Soft tissue tumors and treatment
- Bone Tumor Diagnosis and Treatments
- Cardiac Structural Anomalies and Repair
- Breast Implant and Reconstruction
- Patient-Provider Communication in Healthcare
- Liver Disease Diagnosis and Treatment
- Healthcare Systems and Technology
- Additive Manufacturing and 3D Printing Technologies
- Gallbladder and Bile Duct Disorders
- Ear and Head Tumors
- Neurosurgical Procedures and Complications
- 3D Printing in Biomedical Research
- Pediatric Hepatobiliary Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
Pioneer (United States)
2023
University of California, Los Angeles
2020-2022
UCLA Health
2021-2022
Brown University
2018-2022
Core Laboratories (United States)
2020-2021
Abstract Objective Salivary duct carcinoma (SDC) is a rare and aggressive salivary gland malignancy. Herein, we present the largest single‐institution review of SDC to date. Methods This retrospective cohort study all histologically confirmed cases seen at our institution from January 1, 2002, August 2022. Patient demographics, treatment, histological characteristics, tumor staging, outcomes were extracted electronic medical record. Kaplan‐Meier Cox regression survival analyses performed....
Dysregulation of extracellular matrix (ECM) synthesis, organization, and mechanics are hallmark features diseases like fibrosis cancer. However, most in vitro models fail to recapitulate the three-dimensional (3D) multi-scale hierarchical architecture collagen-rich tissues as a result, unable mirror native or disease phenotypes. Herein, using primary human fibroblasts seeded into custom fabricated 3D non-adhesive agarose molds, novel strategy is proposed direct morphogenesis engineered...
Frailty has been associated with poorer surgical outcomes and is a critical factor in procedural risk assessment. The objective of this study to assess the impact frailty on patients endometrial cancer.
Liver transplantation (LT) is a life-saving treatment for end-stage liver disease patients that requires significant resources. We used national data to evaluate LT outcomes and factors associated with hospital resource use.Using the National Inpatient Sample, we identified all undergoing from 2009 2017 defined high-resource use (HRU) as having costs ≥ 90th percentile. Hierarchical regression models were assess length of stay (LOS) HRU.Over study period, approximately 53,000 underwent LT,...
Extracorporeal life support (ECLS) has been increasingly utilized to manage cardiac and pulmonary dysfunction. The impact of obesity on outcomes ECLS is poorly defined. purpose the study was compare in-hospital mortality, resource use, complications, readmissions in obese versus non-obese patients receiving ECLS. We performed a retrospective cohort all adult with without an diagnosis using 2010-2016 Nationwide Readmissions Database (NRD). Mortality, length stay (LOS), hospital charges, were...
Introduction Improved evidence-based guidelines on the optimal type and duration of antibiotics for patients undergoing endoscopic endonasal transsphenoidal surgery (EETS) are needed. We analyze infectious complications among a large cohort EETS standardized regimen cefazolin 24 hours, followed by cephalexin 7 days after (clindamycin if penicillin/cephalosporin allergic). Methods A retrospective review 132 from 2018 to 2020 was conducted. Patient, tumor, surgical characteristics were...
The literature on opiate use after endoscopic endonasal transsphenoidal surgery (EETS) is limited.To determine the risk factors for higher following EETS and quantity of opiates used discharge.A retrospective review 144 patients undergoing from July 2018 to 2020 was conducted. Patient, tumor, surgical were documented. Pain scores medications postoperative days (POD) 0 1, discharge prescriptions, recorded. Opiate quantified using morphine milligram equivalents (MME) dose. Multiple linear...
<h3>Introduction</h3> Frailty has been associated with poorer surgical outcomes and is a critical factor in procedural risk assessment. The objective of this study to validate patients undergoing surgery for endometrial cancer (EC). <h3>Methods</h3> Patients inpatient gynecologic EC were identified using the 2005–2017 National Inpatient Sample database. Johns Hopkins Adjusted Clinical Groups (ACG) frailty-defining diagnosis indicator was used designate frailty. Multivariate regression models...
Introduction: Cerebrospinal fluid (CSF) leak, both during or after surgery, is a risk for all patients undergoing endoscopic transnasal transsphenoidal (eTNTS) tumor resection. The following factors have been identified in the literature intraoperative CSF leaks: smoking, increased BMI, older age, prior TNTS, suprasellar extension, size, irregularity, consistency, nonfunctional tumors, gonadotrophic-positive staining and preoperative gonadotrophic hormone abnormalities, concurrent...
Introduction: Endoscopic endonasal approaches (EEA) for resection of both craniopharyngiomas and anterior skull base meningiomas are gaining widespread acceptance as the literature has shown comparable rates success complications relative to open craniotomy. However, insufficient data have been published thus far on patient reported outcomes quality life (QOL) after surgery, specifically comparing differences in postoperative (post-op) changes between pathologies similar locations undergoing...
To report a rare case of copious sialoliths from single submandibular gland and Wharton duct provide readers with management consideration for similar patients. A 55-year-old-man presented to otolaryngology clinic recurrent sialolithiasis refractory transoral removal. Upon excision interventional sialoendoscopy, the patient is found have over 40 stones within duct. history excessive stone formation may prompt earlier aggressive prophylactic treatment avoid symptomatic recurrence.
Introduction: Endoscopic endonasal approaches (EEA) for resection of anterior skull base meningiomas are gaining widespread acceptance as the literature has shown comparable rates complications and morbidity relative to open craniotomy approaches. However, insufficient data have been published thus far on patient reported outcomes quality life (QOL) measures, specifically focusing their wellbeing. Given that QOL measures critically informative patient-centered decision making in surgical...
Introduction: Infectious complications of endoscopic endonasal transsphenoidal surgery (EETS) include meningitis and sinusitis. Current rates in the literature are 0.5 to 14% for 3.6 9.6% Despite utility prophylactic antibiotics, there remains a need improved evidence-based guidelines on optimal dosage timescale upon which administer antibiotics. We analyze infectious outcomes, along with potential risk factors contributing among large cohort patients undergoing EETS.
Introduction: Endoscopic endonasal approaches (EEA) for resection of anterior skull base meningiomas are gaining widespread acceptance as the literature has shown comparable rates complications and morbidity relative to open craniotomy approaches. However, insufficient data have been published thus far on patient-reported outcomes quality-of-life (QOL) measures, specifically focusing their well-being. Given that QOL measures critically informative patient-centered decision making in surgical...