A5071230555- Immunotherapy and Immune Responses
- Cancer Research and Treatments
- Histone Deacetylase Inhibitors Research
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Circular RNAs in diseases
- Head and Neck Surgical Oncology
- Vascular Malformations Diagnosis and Treatment
- Epigenetics and DNA Methylation
- CAR-T cell therapy research
- Neurofibromatosis and Schwannoma Cases
- Pituitary Gland Disorders and Treatments
- Vestibular and auditory disorders
- Receptor Mechanisms and Signaling
- Intracranial Aneurysms: Treatment and Complications
- Ocular Oncology and Treatments
- Brain Metastases and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA Interference and Gene Delivery
- Facial Nerve Paralysis Treatment and Research
- Cerebrospinal fluid and hydrocephalus
- Venous Thromboembolism Diagnosis and Management
- Ear Surgery and Otitis Media
- Hearing, Cochlea, Tinnitus, Genetics
- Teratomas and Epidermoid Cysts
UCLA Health
2018-2024
The University of Texas Southwestern Medical Center
2024
Neurological Surgery
2012-2023
University of Miami
2023
University of California, Los Angeles
2019-2023
Ronald Reagan UCLA Medical Center
2019-2022
Princeton University
2021
Oxford University Press (United Kingdom)
2020
APLA Health
2020
University of Pennsylvania
2019
Object Extent of resection (EOR) has been shown to be an important prognostic factor for survival in patients undergoing initial glioblastoma (GBM), but the significance EOR at repeat craniotomy recurrence remains unclear. In this study authors investigate impact and GBM on overall survival. Methods Medical records were reviewed all University California San Francisco Center from January 1, 2005, through August 15, 2009. Patients who had a second pathologically confirmed following radiation...
Ependymoma is the most common glial tumor of adult spinal cord. Current consensus recommends surgical resection with gross total (GTR) whenever possible. We performed a comprehensive review literature to evaluate whether adjuvant radiotherapy after subtotal (STR) has any benefit. A PubMed search was identify patients cord ependymoma who underwent resection. Only had clearly defined extent or without were included for analysis. Kaplan-Meier and multivariate Cox regression survival analyses...
CNS myelin is strongly inhibitory to growing axons and thought be a major contributor axon regenerative failure. Although number of proteins present in myelin, including Nogo, MAG, oligodendrocyte-myelin glycoprotein (OMgp), have been identified as myelin-associated inhibitors, studies mice lacking these genes suggest that additional inhibitors remain identified. Here we investigated the hypothesis lipids contribute We sulfatide, constituent novel inhibitor neurite outgrowth. Sulfatide, but...
OBJECT There are few and conflicting reports on the effects of delayed initiation chemoradiotherapy survival patients with glioblastoma. The standard care for newly diagnosed glioblastoma is concurrent radiotherapy temozolomide chemotherapy after maximal safe resection; however, optimal timing such therapy poorly defined. Given lack consensus in literature, authors performed a retrospective analysis Cancer Genome Atlas (TCGA) database to investigate effect time from surgery METHODS Patients...
Glioblastoma multiforme is the most malignant type of primary brain tumor with a poor prognosis. These tumors consist heterogeneous population cells, including well-differentiated cells and less differentiated stem cell properties. cancer known as initiating likely contribute to glioma recurrence, they are highly invasive, mobile, resistant radiation chemotherapy, have capacity self-renew. release excitotoxic levels glutamate, which may be key process in death peritumoral neurons, formation...
Mechanisms of invasion in glioblastoma (GBM) relate to differential expression proteins conferring increased motility and penetration the extracellular matrix. CD97 is a member epidermal growth factor seven-span transmembrane family adhesion G-protein coupled receptors. These facilitate mobility leukocytes into tissue. In this study we show that expressed glioma, has functional effects on invasion, associated with poor overall survival. Glioma cell lines low passage primary cultures were...
INTRODUCTION: The impact of patient demographics and socioeconomic factors on healthcare outcomes in neurosurgical oncology is gaining greater recognition. METHODS: A retrospective analysis was conducted patients undergoing meningioma resection. Insurance status at time resection, preoperative health status, Modified Rankin Scores (mRS), Karnofsky Performance (KPS), tumor characteristics, radiographic findings from publicly (Medicare, Medicaid, VA) privately insured (all private insurer...
<p>Fig S2 A-C</p>
<p>Fig S6 A-F</p>
<p>Isoplexis fluorescence values per cytokine cell</p>
<p>Fig S5 A-F</p>
<p>Fig S4 A-C</p>
<p>Fig S1A-D</p>
<p>hERV raw counts and FPKM values</p>
<p>Fig S3 A-C</p>