A5041744258- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Opioid Use
- Cardiovascular Issues in Pregnancy
- Maternal and fetal healthcare
- Nausea and vomiting management
- Surgical site infection prevention
- Anesthesia and Sedative Agents
- Neonatal Respiratory Health Research
- Spine and Intervertebral Disc Pathology
- Congenital Diaphragmatic Hernia Studies
- Spinal Dysraphism and Malformations
- Anesthesia and Neurotoxicity Research
- Pediatric Pain Management Techniques
- Maternal and Perinatal Health Interventions
- Clinical practice guidelines implementation
- Tracheal and airway disorders
- COVID-19 and Mental Health
- Hospital Admissions and Outcomes
- Cerebrospinal fluid and hydrocephalus
- Teratomas and Epidermoid Cysts
- Veterinary Pharmacology and Anesthesia
- Pain Management and Placebo Effect
- Sleep and Work-Related Fatigue
- Enhanced Recovery After Surgery
Johns Hopkins Medicine
2011-2024
Johns Hopkins University
2013-2024
University of Ulster
2024
Johns Hopkins Hospital
2009-2021
Pediatrics and Genetics
2021
Fetal Medicine Foundation
2021
Society for Maternal-Fetal Medicine
2021
Intensive Care Society
2021
Fetoscopic myelomeningocele (MMC) repair is performed using intrauterine carbon dioxide (CO2 ) insufflation. Sheep experiments have shown that CO2 insufflation associated with significant fetal acidemia; however, corresponding data for human pregnancy are not available. We umbilical venous cord blood sampling in three patients during fetoscopic MMC at 25 + 1, 3 and 24 0 weeks' gestation, respectively. Fetal pH the beginning of was 7.36, 7.46 7.37, respectively fetuses, repeat values were...
To assess feasibility and maternal infant outcome after fetoscopic tracheal balloon occlusion in patients with severe congenital diaphragmatic hernia.We conducted a prospective cohort study of fetuses hernia observed/expected lung/head ratio less than 30%. Eligible women had planned at 26 0/7-29 6/7 weeks gestation removal 4-6 later. Standardized prenatal postnatal care was single institution. Fetoscopic details, lung growth, obstetric complications, birth outcome, details until discharge...
Between May 29 and September 13,1991,4 patients developed acute intravascular hemolysis during hemodialysis with Monitral-S delivery systems Hospal BSM A77 blood lines. All had malaise, nausea headache; 3 severe abdominal pain 2 became very ill. Plasma hemoglobins were 3-21 g/l LDH 542-3,300 IU in the 4 patients. Hepatoglobin unmeasurable was 0.09 4th patient. Soon afterwards, we found arterial line tightly kinked at dialyzer inlet port patient released it; he pain, present. We then these...
Prenatal closure of open spina bifida via fetal surgery improves neurologic outcomes for infants in selected pregnancies. Fetoscopic techniques that are minimally invasive to the uterus aim provide equivalent benefits while minimizing maternal morbidities, but optimal technique is undetermined. We describe development, evolution, and feasibility laparotomy-assisted 2-port fetoscopic prenatal a newly established program.We conducted retrospective cohort study women consented isolated bifida....
<h3>Background</h3> Many epidural and peripheral nerve catheters contain conducting wire that could heat during magnetic resonance imaging (MRI), requiring removal for scanning. <h3>Methods</h3> We tested 2 each of 6 brands regional analgesia (from Arrow International [Reading, Pennsylvania], B. Braun Medical Inc [Bethlehem, Smiths Medical/Portex [Keene, New Hampshire]) exposure to clinical 1.5- 3-T MRI. Catheters testing as nonmagnetic were placed in an configuration a standard human...
This review describes an in-depth analysis of the neurotoxicity associated with anesthetic agents used during fetal surgery, intending to highlight importance understanding effects general anesthetics on developing brain, particularly in context open where high doses are applied facilitate surgical access and augment uterine relaxation. We examined evidence from preclinical studies rodents primates, along human subjects, results collectively suggesting that can disrupt brain development lead...
( Reg Anesth Pain Med . 2016;41(6):763–772) In 2007, there were 1.4 million cesarean deliveries (1 in 3 live births) the United States alone. after delivery can be severe many patients, with 78% of women undergoing reporting moderate to postoperative pain within first 24 hours postoperatively. Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective treatment this despite them being generally viewed as “weak” analgesics. This meta-analysis was conducted assess analgesic efficacy NSAIDs...