A5075797873- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Hormonal and reproductive studies
- Menopause: Health Impacts and Treatments
- Estrogen and related hormone effects
- Cardiovascular Issues in Pregnancy
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Cardiovascular Health and Risk Factors
- Sex and Gender in Healthcare
- Cardiac electrophysiology and arrhythmias
- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pregnancy and preeclampsia studies
- Cardiovascular and exercise physiology
- Cerebrovascular and Carotid Artery Diseases
- Hormonal Regulation and Hypertension
- Birth, Development, and Health
- Coronary Interventions and Diagnostics
- Nutrition and Health in Aging
- Cardiovascular Effects of Exercise
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease Diagnosis and Treatment
Johns Hopkins University
2016-2025
Johns Hopkins Medicine
2016-2025
Beike Biotechnology (China)
2025
First Affiliated Hospital of Jinan University
2024
Chang Gung University
2019-2024
Vanderbilt University Medical Center
2017-2024
Sahlgrenska University Hospital
2024
University of Gothenburg
2024
Knowles (United States)
2023
Saint John's Health Center
2023
HomeCirculationVol. 109, No. 5Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women
There is substantial evidence that coronary calcification, a marker for the presence and quantity of atherosclerosis, higher in US whites than blacks; however, there have been no large population-based studies comparing calcification among ethnic groups.Using computed tomography, we measured 6814 white, black, Hispanic, Chinese men women aged 45 to 84 years with clinical cardiovascular disease who participated Multi-Ethnic Study Atherosclerosis (MESA). The prevalence (Agatston score >0)...
We examined the prevalence and prognostic importance of silent myocardial ischemia detected by continuous electrocardiographic monitoring in 70 patients with unstable angina. All received intensive medical treatment nitrates, beta-blockers, calcium-channel blockers. Continuous recordings were made during first two days coronary care unit to quantify frequency duration asymptomatic ischémie episodes, defined as a transient ST-segment shift 1 mm or more. Thirty-seven (Group 1) had at least one...
2][3][4][5] Estrogen exerts beneficial effects on blood lipids, lowdensity lipoprotein (LDL) oxidation, vascular function, and some aspects of the coagulation system. 6Yet hormone replacement therapy (HRT) was not shown to be in only 2 randomized, placebo-controlled trials postmenopausal women with coronary disease. 7-9Furthermore, large primary prevention trial HRT re-
Objective Cardiovascular disease is the number one killer of women. Identifying women at risk cardiovascular has tremendous public health importance. Early menopause associated with increased events in some predominantly white populations, but not consistently. Our objective was to determine if self-reported early (menopause an age <46 y) identifies as for future coronary heart or stroke. Methods The study population came from Multi-Ethnic Study Atherosclerosis, a longitudinal, ethnically...
Worldwide clinical practice guidelines for dyslipidemia emphasize allocating statin therapy to those at the highest absolute atherosclerotic cardiovascular disease (CVD) risk.We examined 5534 Multi-Ethnic Study of Atherosclerosis (MESA) participants who were not on baseline medications dyslipidemia. Participants classified by coronary artery calcium (CAC) score (>0, ≥ 100) and common scheme counting lipid abnormalities (LA), including low-density lipoprotein cholesterol 3.36 mmol/L (130...
<h3>Background</h3> Because of age-related differences in the cause hypertension, it is uncertain whether current exercise guidelines for reducing blood pressure (BP) are applicable to older persons. Few studies persons have evaluated BP changes relation body composition or fitness. <h3>Methods</h3> This was a 6-month randomized controlled trial combined aerobic and resistance training; controls followed usual care physical activity diet advice. Participants (aged 55-75 years) had untreated...
We assessed the efficacy of adding nifedipine to conventional treatment unstable angina in 138 patients a prospective, double-blind, randomized, placebo-controlled trial. There was no difference between two groups dose antianginal medication or age, prior myocardial infarction, ejection fraction, other risk factors. Failure medical (defined as sudden death, bypass surgery within four months) occurred In 43 70 given placebo and 30 68 nifedipine. KapIan–Meier survival-curve analysis number...
Clinical trials have demonstrated that, compared with placebo, intensive statin therapy reduces ischemia in patients acute coronary syndromes and stable artery disease. However, no studies to date assessed versus moderate older syndromes.A total of 893 ambulatory disease (30% women) 65 85 years age > or = 1 episode myocardial that lasted 3 minutes during 48-hour ECG at screening were randomized atorvastatin 80 mg/d pravastatin 40 followed up for 12 months. The primary efficacy parameter...