A5102780311- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Ottoman and Turkish Studies
- Complementary and Alternative Medicine Studies
- Ottoman Empire History and Society
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Renal Transplantation Outcomes and Treatments
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Acupuncture Treatment Research Studies
- Nitric Oxide and Endothelin Effects
- Cardiac Ischemia and Reperfusion
- Organ Transplantation Techniques and Outcomes
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Aortic aneurysm repair treatments
- Biochemical effects in animals
- Pulmonary Hypertension Research and Treatments
- Pain Management and Placebo Effect
- Cardiovascular and exercise physiology
- Acute Myocardial Infarction Research
Hacettepe University
1993-2023
Aksaray University
2023
Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi
2023
Sağlık Bilimleri Üniversitesi
2023
Gaziantep University
2019
Bozok Universitesi
2016
Mevlana University
2015
Necmettin Erbakan University
2015
Selçuk University
2009-2014
Columbia University
2001-2010
HomeCirculationVol. 109, No. 5Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women
Background— Cardiac transplantation vasculopathy is the leading cause of late death in heart recipients. Rapamycin an immunosuppressant drug with potent antiproliferative and antimigratory effects. We investigated whether rapamycin could prevent progression graft 46 patients (age, 54±10 years; 4.3±2.3 years after transplantation) severe disease. Methods Results— At annual cardiac catheterization, were randomly assigned to treatment (n=22) versus continued current immunosuppression (n=24)....
Background —Mechanical, histological, and biochemical improvement has been described in patients after left ventricular assist device (LVAD) support. Explantation of the LVADs without heart transplantation selected who received this therapy as a bridge to transplantation. Methods Results —A retrospective review receiving mechanical at Columbia Presbyterian Hospital July 21, 1991, was performed determine incidence whom successfully explanted. From August 1, 1996, February 1998, we...
Background. Pulmonary vascular resistance is often elevated in patients with congestive heart failure, and those undergoing left ventricular assist device (LVAD) insertion, it may precipitate right failure hemodynamic collapse. Because the effectiveness of inotropic vasodilatory agents limited by systemic effects, devices are required. Inhaled nitric oxide (NO) an effective, specific pulmonary vasodilator that has been used successfully management hypertension.Methods. Eleven 23 LVAD...
Background— Left ventricular assist devices (LVADs) induce reverse remodeling of the failing heart except for extracellular matrix, which exhibits additional pathophysiological changes, although their mechanisms and functional consequences are unknown. Methods Results— Hearts were obtained at transplant from patients with idiopathic dilated cardiomyopathy (DCM) not requiring LVAD support (n=30), (n=16; duration, 145±33 days), 5 nonfailing hearts. (LV) right (RV) ex vivo pressure-volume...
Nitric oxide (NO) is a novel biologic messenger with diverse effects but its role in organ transplantation remains poorly understood. Using porphyrinic microsensor, the first direct measurements of coronary vascular and endocardial NO production were made. was measured directly effluent preserved, heterotopically transplanted rat hearts stimulated L-arginine bradykinin; concentrations fell from 2.1 +/- 0.4 microM for freshly explanted to 0.7 0.2 0.08 preserved 19 38 h, respectively. levels...
Background. Extremes in body weight are a relative contraindication to cardiac transplantation. Methods. We retrospectively reviewed 474 consecutive adult patients (377 male, 97 female, mean age 50.3±12.2 years), who received 444 primary and 30 heart retransplants between January of 1992 1999. Of these, 68 cachectic (body mass index [BMI]<20 kg/m2), 113 overweight (BMI=>27–30 55 morbidly obese (BMI>30 kg/m2) were compared with 238 normal-weight recipients (BMI=20–27 kg/m2). evaluated the...
Objectives. Our recent experience with outpatient left ventricular assist device (LVAD) support is presented to demonstrate the possibilities and limitations of long-term mechanical circulatory assistance. Background. The inpatient LVAD as a bridge transplantation has proved efficacy such therapy in improving hemodynamic status, restoring normal end-organ function facilitating patient rehabilitation. With miniaturization power supplies controllers, can now be accomplished an setting....
Background. Heparin resistance is an important clinical problem traditionally treated with additional heparin or fresh frozen plasma. We undertook a randomized trial to determine if treatment antithrombin (AT) concentrate effective for treating this condition.Methods. Patients requiring cardiopulmonary bypass who were considered be resistant (activated clotting time < 480 seconds after > 450 IU/kg heparin) receive either 1000 U AT heparin.Results. was in 42 of 44 patients (96%) immediately...
Background —Our objective for this study was to investigate whether nitric oxide (NO) modulates tissue respiration in the failing human myocardium. Methods and Results —Left ventricular free wall right samples were taken from 14 explanted hearts at time of transplantation. Tissue oxygen consumption measured with a Clark-type electrode an airtight stirred bath containing Krebs solution buffered HEPES 37°C (pH 7.4). Rate decrease concentration expressed as percentage baseline, results highest...
The objectives of this study are to determine risk factors associated with deep sternal wound infections (DSWIs) following cardiac surgery, and describe their impact on long-term survival. Data was obtained from a departmental database. Analysis included 7,978 consecutive patients who underwent surgery between 1997 2003. To identify for DSWI, regression analysis performed. probability scores logistic were used propensity 2 groups. Kaplan-Meier log-rank test Cox proportional hazard models...