To determine the prevalence of keratoconus (KC) in students and faculty members (aged ≥18 ≤30 years) studying/working at Medical Health Sciences faculties Eskişehir Osmangazi University.Eskişehir University, Eskişehir, Turkey.Prevalence study.Subjects were randomly selected to undergo KC screening using a proportional stratified sampling method. Of 648 invited subjects, 585 (90.3%) responded invitation. The demographic data, medical/family history, habits subjects collected standardized...

Inflammatory mediators that infiltrate the corneal stroma after infections, trauma or refractive surgery can trigger transformation of keratocytes into myofibroblasts, resulting in highly irregular collagen deposition and subsequently scarring. Mesenchymal stem cells (MSCs) be used as therapeutic agents to regenerate conjunctival tissue damage, regulate inflammation, reduce development limbal cell failure. The use MSC-derived exosomes a cell-free vector is novel approach. This study aimed...

Objectives: To evaluate the performance of convolutional neural network (CNN) architectures to distinguish eyes with glaucoma from normal eyes.Materials and Methods: A total 9,950 fundus photographs 5,388 patients database Eskişehir Osmangazi University Faculty Medicine Ophthalmology Clinic were labelled as glaucoma, suspect, or by three different experienced ophthalmologists.The categorized evaluated using a state-of-the-art two-dimensional CNN compared deep residual networks (ResNet) very...

Purpose: To develop a combined biomechanical and tomographic model for identifying eyes with subclinical keratoconus (SKC) that are categorized as normal or borderline in the Pentacam Belin/Ambrósio Enhanced Ectasia Display. Methods: This case–control study comprised 62 SKC randomly selected of 186 age-matched healthy controls. was defined presence following: 1) topography, topometric indices, slit lamp; 2) Display D index, back front elevation difference; 3) fellow eye. Stepwise logistic...

In addition to risk factors such as low birth weight and uncontrolled oxygen therapy, genetic predisposition is also thought play a role in the development of retinopathy prematurity (ROP). our study, we aimed analyze single-nucleotide polymorphisms (SNPs) VEGFA, EPAS1, BDNF NOS3 genes infants who develop ROP.Seventy-five mild-moderate 73 severe ROP cases were included this study. Eleven different SNPs regions that located analysed by SnapShot technique compared between two groups multiple...

To evaluate the corneal epithelial thickness (CET) profiles and their correlations with axial length (AL) anterior radius of curvature (Rm F) across different refractive error groups.A total 1225 eyes 616 normal patients were included. CET mapping, AL, Rm F obtained using spectral-domain optical coherence tomography, biometry, Scheimpflug respectively. In map, one central (2 mm), eight paracentral (2-5 peripheral (5-6 mm) quadrants evaluated separately. The subjects divided into four groups...

To assess phosphate and osmolarity levels of chronically administered eye drops commercially available in Turkey.A total 53 topical including 18 antiglaucoma drugs, 4 nonsteroidal anti-inflammatory drugs (NSAIDs), 10 corticosteroids, 7 antihistaminics, 14 artificial tears identified using the Vademecum Modern Medications Guideline (2018) were included study. Phosphate assessed Roche Cobas C501 analyzer (Roche Diagnostics GmbH, Mannheim, Germany) respective kits. Osmolarity was Vescor Vapro...

Purpose: To evaluate blood levels of vitamin B12, folic acid, riboflavin, and homocysteine in keratoconus (KC) healthy subjects. Setting: Eskişehir Osmangazi University, Eskişehir, Turkey. Design: Cross-sectional study. Methods: 100 KC patients (patient group) between the ages 18 to 35 years 200 individuals (control same age range were included University Hospital Eye Clinic October 2019 March 2020. In all cases, a complete ophthalmologic examination corneal tomography evaluation with...

Objectives:The aim of this study was to investigate the distribution microbial agents in early and late postoperative periods patients with keratitis (MK) after penetrating keratoplasty (PK). Materials Methods:The records 36 who were clinically diagnosed as having MK PK retrospectively reviewed.Culture results obtained from microbiology organisms that produced noted.A case deemed viral based on clinical appearance, negative cultures, response antiviral treatment.Keratitis development times...

Aims/Purpose: Melatonin is a time‐and‐concentration dependent pro and antiinflammatory agent that also regulates cell proliferation, migration, angiogenesis, fibrosis, extracellular matrix synthesis. This study aims to assess the effect of exosomes obtained from melatonin‐treated human limbal mesenchymal stem cells (hLMSCs) on naive hLMSCs ascertain their influence antifibrotic proregenerative pathways involved in corneal scarring. Methods: were harvested eye bank Eskişehir Osmangazi...

Aims/Purpose: The aim of this study was to comparison waveform‐derived Ocular Response Analyser (ORA) parameters in clinical keratoconus (KC), subclinical (SKC) and healthy subjects. Methods: This retrospective comparative case series included 24 eyes with SKC, KC 48 age‐ sex‐matched Keratoconus diagnosis based on examinations, Scheimpflug corneal tomography. SKC defined as the presence following: (1) normal biomicroscopic findings topography; (2) anterior (≤7 μm) posterior (≤16 elevation...

Aims/Purpose: In this study we aimed to investigate miRNAs associated with scarless wound healing in limbal‐derived stomal‐mesenchymal stem cells (hLMSC) and orbital adipose tissue‐derived (hOA‐MSC) treated individually vitamin C exosomes obtained after treatment. Methods: Isolation characterization of hLMSCs hOA‐MSCs were performed. MTT assay was employed determine the ideal non‐cytotoxic proliferative concentration (vit C). The selected applied cell culture medium C‐treated) followed by...

With low supply and high demand for donor corneas, we surveyed Turkish participants on level of knowledge, awareness, willingness toward cornea donation.

To determine corneal biomechanical and tomographic factors associated with keratoconus (KC) progression.This study included 111 eyes of KC patients who were followed-up for at least 1 year. Progression was defined as the presence progressive change between first two consecutive baseline visits in any single parameter (A, B, or C) ≥95% confidence interval parameters ≥80% population evaluated by Belin ABCD progression display. The eye better initial findings chosen eye. Analyzed Pentacam...

Aims/Purpose: We aimed to evaluate the function‐vasculature, and function–structure relationships in advanced glaucoma patients. Methods: This cross‐sectional study included 29 eyes of 24 Advanced was classified as visual fields (VFs) with a mean deviation (MD) below ‐12 dB according Hodapp‐Parrish‐Anderson classification system. The structural parameters, cup/disc area ratio, vertical horizontal rim area, disc cup volume, retinal nerve fibre layer thickness, macular ganglion cell complex...

In the low-weight newborn patient group, development of catheter related bloodstream infections after cardiac surgery significantly impacts morbidity and mortality. our study, effects choosing femoral or internal jugular vein localization in newborns on postoperative infection will be examined. Our hypothesis is that there may a higher risk region. This study was conducted retrospectively cases who underwent congenital heart between September 1, 2020, March 2022. The were divided into 2...

High levels of iron may be toxic and cause various pathologies in the human body, including eye. Studies have shown increased concentration certain subtypes senile cataracts. serum its non-reactive depot form, ferritin, has also been associated with juvenile cataracts hereditary hyperferritinemia-cataract syndrome. Whereas this form hyperferritinemia is inherited, there no report on cataract formation iatrogenic hyperferritinemia. Herein, we a 43-year-old case who was diagnosed bilateral few...

ABSTRACT Aim To report an unusual case of a newly diagnosed bilateral superior keratoconus in elderly patient. Background We 64-year-old woman who was after having presented with hydrops one eye. Case description Uncorrected visual acuity counting fingers from 3 and 1 meter for the right left eyes, respectively. A superiorly located deep stromal scar chronic corneal edema consistent diagnosis were noted Although cornea clear, there protrusion Pentacam Orbscan demonstrated overlapping focal...

Population Medicine considers the following types of articles:• Research Papers -reports data from original research or secondary dataset analyses.• Review -comprehensive, authoritative, reviews within journal's scope.These include both systematic and narrative reviews.• Short Reports -brief reports research.• Policy Case Studies articles on policy development at a regional national level.• Study Protocols -articles describing protocol study.• Methodology -papers that present different...

The evaluation of cases operated for vertical deviation. Materials and Methods: Cases between January 2015 June 2016 followed-up at least 1 year were evaluated. Pre postoperative angle deviations (PD), inferior oblique muscle (IO) functions, refractive errors, etiologies surgeries performed noted. Success was defined as alignment with 10 PD orthophoria and/or overaction (IOOA) ≤+1 the final examination. 32 out 172 cases, surgery due to deviation performed. Primary IOOA (group 1; n=19; 15...

BackgroundTo assess pointwise corneal elevation changes after forced eyelid closure test (FECT) in the eyes of healthy subjects and with keratoconus.MethodsTwenty‐nine keratoconus 31 volunteers were evaluated. Patients who had hydrops, apical scarring, thickness ≤ 400 μm, ocular surface disease, contact lens wear on examination day a history cross‐linking excluded. Exclusion criteria for participants spherical error > +3.00 D < −3.00 D, astigmatism 1.50 curvature 47 allergy, clinical...