Inflammatory mediators that infiltrate the corneal stroma after infections, trauma or refractive surgery can trigger transformation of keratocytes into myofibroblasts, resulting in highly irregular collagen deposition and subsequently scarring. Mesenchymal stem cells (MSCs) be used as therapeutic agents to regenerate conjunctival tissue damage, regulate inflammation, reduce development limbal cell failure. The use MSC-derived exosomes a cell-free vector is novel approach. This study aimed...

To evaluate the outcomes of penetrating keratoplasty performed for therapeutic and tectonic purposes in eyes with perforated infectious corneal ulcer.This retrospective study included 43 patients who developed ulcer various etiological causes between June 2008 January 2018. The were evaluated based on age sex, follow-up time, presence perforation, pre- postoperative visual acuity, graft transparency, complications, infection recurrence.The mean was 52.9±13.8 years. time 2.7±1.3...

Purpose: This study aimed to investigate the long-term effects of COVID-19 on corneal endothelial cell morphology in patients with ocular symptoms assess possible involvement who recovered. Methods: The group included diagnosed and treated at Istanbul University Cerrahpasa Medical Faculty confirmed SARS-CoV-2 infection irritation symptoms. control was comprised age- sex-matched individuals. controls had no pathologies. Noncontact specular microscopy (Konan Cell Check SL, Hyogo, Japan)...

Orbital tissue infections are common of childhood that can lead to severe complications. Herein, we aimed evaluate the etiologic factors, diagnosis, follow-up, and treatment procedures in pediatric patients with orbital infections.This study was performed retrospectively between January 2014 December 2015 Cerrahpasa Medical Faculty Pediatric Infectious Disease Unit. Patients were studied for age, ophthalmologic examination features, laboratory radiology results, modalities, response these...

Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity additional in treatment thyroid orbitopathy related strabismus. In this study, reviewing results our patients who had surgical correction relaxed muscle positioning technique due to strabismus evaluate effectiveness surgery was aimed.The medical records 8 intraoperative (IRMP) were studied retrospectively. The extent determined prism cover test both at near distance. recession by marking...

To evaluate the 6-month outcomes of Descemet membrane endothelial keratoplasty (DMEK) in patients with pseudophakic bullous keratopathy (PBK) and Fuchs’ dystrophy (FED) a single center Turkey.The medical records who underwent DMEK were reviewed retrospectively. Best corrected visual acuity (BCVA), donor corneal cell density (ECD), age, duration solution after obtaining tissue, exitus evaluated preoperatively BCVA, ECD, ECD loss (%) at postoperative 6 months postoperatively. Graft detachment,...

Purpose: To investigate the change in pre- and post-dilation anterior segment parameters intraocular pressure (IOP) of patients with without pseudoexfoliation, after topical application phenylephrine HCl 10% tropicamide 1%.Materials methods: Totally 129 eyes were included study. Of eyes; 31 had pseudoexfoliation syndrome (PXS), 37 glaucoma (PXG), fellow subjects unilateral (subclinical PXS) 30 PXS (controls). Patients underwent Pentacam analysis IOP measurement before dilation. The changes...

Purpose: To investigate the blood flow changes in choriocapillaris and superficial deep capillary plexus of retina using optic coherence tomography angiography (OCTA) patients with Fabry disease (FD) reveal any possible association these systemic findings. Methods: This cross-sectional study included 38 FD age- gender-matched 40 healthy controls. OCTA images were obtained from all patients. Superficial (sCVD) vascular density (dCVD) foveal, parafoveal, perifoveal zones whole image recorded...

Abstract In renal transplantation, living donations have more significant benefits compared to cadaveric donations. However, a probable increase in blood pressure following donation should also be kept mind. this study, we investigated the long‐term changes kidney donors using ambulatory monitoring and explored e‐ GFR albuminuria/proteinuria measurements at 3 time points. Twenty‐eight 39 healthy individuals were evaluated baseline later 10th year. At year, creatinine levels higher eGFR lower...

To compare the changes in corneal endothelial cells of both patients with keratoconus who use rigid gas-permeable (RGP) contact lens and do not any healthy population.Thirty-three RGP lenses (group 1), 20 2), 40 controls were included study. Changes all evaluated using a noncontact specular microscope. Endothelial cell density (ECD), coefficient variability (CV), hexagonal percentage (%HEX), central thickness (CCT) study.In groups 1, 2, 3, mean ECD was 2,420.8±247, 2,579.5±240, 2,589.5±271...

The purpose of this study was to evaluate the in vitro antifungal effects n-butyl-2-cyanoacrylate (nB2CA; Histoacryl Blue; B. Braun, Melsungen, Germany) against a variety different fungal species.Inocula taken from suspensions prepared with Aspergillus flavus, fumigatus, niger, ochraceus, oryzae, Fusarium solanii, oxysporum, Trichoderma spp., Rhizomucor Scedosporium apiospermum, Penicillium commune, Phoma glomerata, and Chrysosporium spp. molds Candida albicans, glabrata, parapsilosis,...

Pediatric cataract surgery differs substantially from adult surgery. Numerous studies have focused on reducing the development of postoperative complications.To compare two intraocular lens implantation techniques used in pediatric terms complications.Case-control study.Patients who underwent and between 2008 2016 were evaluated this retrospective study. Patients aged 3-15 years with unilateral or bilateral without corneal pathology included The patients categorized into following groups:...

Objectives: To evaluate the effect of corneal subepithelial infiltrates (SEIs) on tear film function and best-corrected visual acuity (BCVA) after persistent epidemic keratoconjunctivitis (EKC) to compare findings with controls. Methods: In this prospective, cross-sectional study, 38 patients EKC 42 healthy volunteers were enrolled. While SEIs made up groups 1a (first involved eye) 1b (second eye), controls group 2. Best-corrected acuity, infiltrate scoring (CSIS), Fantes score, breakup time...

Background: Development of endophthalmitis during cataract surgery is one the most severe complications and it may also result in blindness globe loss.Aims: To evaluate effect an ophthalmic cefuroxime solution (Aprokam ® ) that prophylactically used phacoemulsification performed due to eventually occurs patients with or without penetrating keratoplasty.Study Design: Case-control study.Methods: In this retrospective study, who had undergone keratoplasty for whom was intracameral administered...

Objective:  Investigation of the effect globe injury site and type on postoperative results in patients with a relatively softer open (OGI) was aimed. Methods: Medical records OGI due to blunt or penetrating trauma were analyzed retrospectively. The patient cohort divided into laceration rupture groups. location evaluated zones (I-II-III). Presence complication (cataract, retinal detachment, etc.) evaluated. Final best-corrected visual acuity (BCVA) as primary outcome measure....

To determine the effects of intravitreally injected aspirin on normal ocular tissues.Six eyes 3 rabbits as a control group, 18 9 albino which were studied. In same volume balanced salt solution (BSS) in drug groups injected. Clinical examination methods including biomicroscopy, indirect ophthalmoscopy, and Schiotz tonometry, electrophysiological test ERG, histopathological light microscopy used to evaluate after injections. All study tests performed before injections 1 week, month, months...

To compare dry eye parameters in prolactinoma patients and healthy controls evaluate their correlation with prolactin (PRL) levels the duration of hyperprolactinemia.Consecutive were included study. Schirmer, tear break-up time (TBUT), osmolarity values, ocular surface disease index (OSDI) scores evaluated for each patient. Follow-up total hyperprolactinemia recorded patients.The study 39 eyes age- gender-matched controls. Prolactinoma showed lower Schirmer (14.1±8.4 vs. 24.8±8.9 mm;...