A5080033177- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Peripheral Neuropathies and Disorders
- Cerebral Venous Sinus Thrombosis
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Hepatitis C virus research
- Cardiovascular Health and Disease Prevention
- Multiple Sclerosis Research Studies
- Neurosurgical Procedures and Complications
- Stroke Rehabilitation and Recovery
- Intensive Care Unit Cognitive Disorders
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Hepatitis B Virus Studies
- Cardiovascular Syncope and Autonomic Disorders
- Neurological Disorders and Treatments
- Aging, Health, and Disability
- Myasthenia Gravis and Thymoma
- Vascular Malformations Diagnosis and Treatment
- Hereditary Neurological Disorders
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2016-2025
Hospital Civil de Guadalajara
2005-2021
NIMS University
2020-2021
Universidad Nacional Autónoma de México
2019
Instituto Nacional de Cardiología
2016
Universidad de Guadalajara
2005-2014
Institute of Medical Sciences
2014
Hospital Universitario de Guadalajara
2014
Instituto Nacional de Neurología y Neurocirugía
2006
Background and Purpose— This study aimed to independently derive an intracerebral hemorrhage grading scale (ICH-GS) for prediction of 3 outcome measures. Methods— We evaluated 378 patients with primary ICH at hospital arrival during the next 30 days. Independent predictors were identified by multivariate models in-hospital 30-day mortality. Points allotted each predictor based on its prognostic performance. ICH-GS was also predict good functional status compared score as reference scoring...
Background The coronavirus disease 2019 (COVID-19) is a systemic entity that frequently implies neurologic features at presentation and complications during the course. We aimed to describe characteristics predictors for developing in-hospital manifestations in large cohort of hospitalized patients with COVID-19 Mexico City. Methods analyzed records from consecutive adult March 15 June 30, 2020, moderate severe confirmed by reverse transcription real-time polymerase chain reaction (rtRT-PCR)...
Cluster headache (CH) is one of the worst primary headaches that remain underdiagnosed and inappropriately treated. There are recent advances in understanding this disease available treatments. This paper aims to review CH's clinical pathophysiological findings, diagnosis, treatment. We performed a narrative literature on socio-demographics, presentations, diagnosis treatment CH. CH affects 0.1% population with an incidence 2.07–9.8/100,00 person-years-habitants, mean prevalence 53/100,000...
<b><i>Background:</i></b> Current evidence shows that uric acid is a potent antioxidant whose serum concentration increases rapidly after acute ischemic stroke (AIS). Nevertheless, the re-lationship between (SUA) levels and AIS outcome remains debatable. We aimed to describe prognostic significance of SUA in AIS. <b><i>Methods:</i></b> studied 463 patients (52% men, mean age 68 years, 13% with glomerular filtration rate <60 ml/min at...
Background: Most patients with cerebral venous thrombosis (CVT) have independent survival in the short term. However, identification of high-risk individuals an unfavorable outcome is a challenging task. We aimed to develop CVT grading scale (CVT-GS) aid short-term clinical decision-making. Methods: included 467 consecutive who were hospitalized from 1981 2015 two third-level referral hospitals. Factors associated 30-day mortality selected bivariate analyses integrate Cox...
Statins are a group of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors aimed at reducing cholesterol synthesis. Since their discovery in 1970, use has exponentially increased, becoming regular preventive treatment for cardiovascular diseases. Among most common adverse effects myopathies, with the severe being autoimmune necrotizing myopathy. We present case woman her 70s, high cardiovascular-risk comorbid conditions, including hypothyroidism, type 2 diabetes, arterial...
Scarce epidemiological information on stroke in Mexico impedes evidence-based decisions and debilitates the design of effective prevention programmes at local level.
Objective To determine stroke prevalence, mechanisms, and long-term outcome in a cohort of Hispanic patients with systemic lupus erythematosus (SLE). Methods We analyzed demographical data, the timing between SLE diagnosis onset, type, recurrence, outcomes from an institutional database 4451 followed 1993 to 2018. Results observed 139 strokes (3.1%), for incidence rate 1.25 per 1000 person-years: 81 (58.3%) acute ischemic (AIS), 19 (13.7%) subarachnoid hemorrhage (SAH), 17 (12.2%) cerebral...
Objective. During the onset of a novel epidemic, there are public health priorities that need to be estimated, such as risk factors for infection, hospitalization, and clinical severity allocate resources issue policies. In this work we calculate infection hospitalization by Covid-19 conferred demographic, lifestyle, co-morbidity factors. Material methods. This is case-control study including tested individuals SARS-Cov-2 RT-PCR officially reported Health Secretary Mexico from January 01 May...
Information on Guillain-Barré syndrome (GBS) as an adverse event following immunization (AEFI) against SARS-CoV-2 remains scarce. We aimed to report GBS incidence AEFI among adult (≥18 years) recipients of 81,842,426 doses seven anti-SARS-CoV-2 vaccines between December 24, 2020, and October 29, 2021, in Mexico.Cases were retrospectively collected through passive epidemiological surveillance. The overall observed was calculated according the total number administered doses. Vaccines analyzed...
Hypertensive intracerebral hemorrhage (ICH) in young people has been the object of only succinct analyses. Therefore, it is unclear whether extrapolation information obtained from older patients also valid for young. Here we describe persons with hypertensive ICH and compare them their counterparts to determine age-related clinical differences exist.From 1988 2004, studied 35 consecutive (60% men; mean age, 33 years; range, 15 40 years) whom etiology brain was hypertension. For comparisons,...
An intriguing feature recently unveiled in some COVID-19 patients is the "silent hypoxemia" phenomenon, which refers to discrepancy of subjective well-being sensation while suffering hypoxia, manifested as absence dyspnea.To describe clinical characteristics and predictors silent hypoxemia hospitalized patients.We conducted a prospective cohort study including consecutive adult (≥ 18 years) with confirmed presenting emergency department oxygen saturation (SpO2) ≤ 80% on room air from March...
<i>Background:</i> The number of persons reaching the age 80 years and over is increasing in most populations. Literature focusing on hypertensive intracerebral hemorrhage (ICH) inthis group lacking. Therefore, we aimed to analyze main clinical characteristics ICH advanced old age, context hypertension. <i>Methods:</i> From 1999 2003 studied 56 very elderly patients presenting with (50% women; 80–99 years). As controls, 168 gender-matched ICH, aged <80 years, were...
Information on acute care and outcome of Mexican patients with ischaemic stroke is lacking. The aim this report to provide results a first step surveillance system at one year follow-up.In the PREMIER study 1,376 from 59 hospitals were included January 2005 June 2006. Of these, 1,040 (52% women, mean age 67.5 years) first-ever cerebral infarction are here analyzed. Five visits completed during follow-up.Main risk factors hypertension (64%), obesity (51%) diabetes (35%). Total anterior...
Background and Purpose— Cerebellar venous infarction or hemorrhage due to isolated thrombosis of the posterior fossa is a rare form intracranial vein that can be unsuspected in clinical practice. Methods— We studied 230 patients with thrombosis, identifying 9 (3.9%: 7 women, mean age 34 years) neuroimaging histopathologic evidence localized causing parenchymal injury limited exclusively cerebellum. Results— All had an insidious presentation suggesting other diagnoses. Intracranial...
Assessing adherence to growth hormone (GH) is challenging. The Easypod™ connect device delivers pre-set doses of recombinant human GH (r-hGH) and stores a digital record that can be shared with healthcare provider. We assessed r-hGH delivered according the approved pediatric indications for r-hGH: deficiency (GHD), born small gestational age (SGA) who failed show catch-up Turner syndrome (TS). ECOS (NCT01555528) was multicenter (24 countries), 5-year, longitudinal, observational study, which...