A5023980120- Diabetes Management and Research
- Diabetes Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Renal Transplantation Outcomes and Treatments
- Obesity and Health Practices
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Thyroid Disorders and Treatments
- Bariatric Surgery and Outcomes
- Mast cells and histamine
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Peroxisome Proliferator-Activated Receptors
- Neuroendocrine Tumor Research Advances
- Obesity, Physical Activity, Diet
- Thyroid Cancer Diagnosis and Treatment
- Biochemical effects in animals
- Heart rate and cardiovascular health
- Adipokines, Inflammation, and Metabolic Diseases
- Hepatitis C virus research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Adolescent and Pediatric Healthcare
- Transplantation: Methods and Outcomes
American Diabetes Association
2013-2018
University of Kentucky
2002-2015
Albert B. Chandler Hospital
2007-2012
United States Department of Veterans Affairs
2012
Lexington VA Health Care System
2002-2008
The Graduate Center, CUNY
2002
St. Columcille's Hospital
2002
The University of Sydney
1990
The advances in recombinant DNA technology have led to an improvement the properties of currently available long-acting insulin analogs. Insulin degludec, a new generation ultra-long-acting basal insulin, phase 3 clinical trials, has promising future use. When compared its rival analogs, longer duration action and lower incidence hypoglycemic events both type 1 2 diabetic patients been demonstrated. , Its unique mechanism is based on multihexamer formation after subcutaneous injection. This...
The population for this study included 186 patients who were treated between 1962 and 1977 diffuse toxic goiter. Patients divided into two groups according to the primary mode of therapy, which was either thioamides or sodium iodide I 131. Of 96 with drug only 16% experienced a prolonged remission (more than years) hyperthyroidism. Except greater likelihood among mild hyperthyroidism, no other clinical features Graves' disease predictive long-term response therapy. Among 90 received 131...
Background: Health professionals are in need of more information about the weight-loss outcomes using commercial programs. Objective: A behavioral intervention program meal replacements, fruits, and vegetables (MR-FV) was compared with usual-care counseling. Design: Obese volunteers were randomly allocated to counseling or participation an MR-FV standardized education program. The group attended weekly classes for 16 weeks maintenance 8 weeks. Participants/Setting: women men aged 20 65 years...
To evaluate the efficacy of a lifestyle intervention programme including meal replacements and increased physical activity upon body weight, diabetes control other cardiovascular risk factors in obese, poorly controlled, insulin-treated, type-2-diabetic individuals to assess impact concomitant rosiglitazone (RSG) therapy.This 6-month study included 21 patients with type 2 mellitus (DM) requiring insulin therapy haemoglobin A1c (HbA1c) > 7% mass index (b.m.i.) 27. All subjects were enrolled...
The emergence of a “critical medical anthropology” offers perspective that can complement and enrich the explanatory model (EM) approach, particularly in case illnesses are polysemic have political economic implications. Repetition strain injury (RSI), an occupational illness which became epidemic Australian industry early 1980s, focus multiple disparate biomedical EMs. We argue debates about etiology RSI be understood terms ideological role medicine reducing to physiological or...
Thionamide drugs are widely used in the management of hyperthyroidism and infrequently associated with adverse reactions. We report development nephrotic syndrome during methimazole (Tapazole) therapy a young man Graves' disease. His proteinuria remitted promptly discontinuance drug, renal histologic features bore striking resemblance to toxic nephrosis induced animals by aminonucleoside puromycin. In view similarities, we propose that acted as direct glomerular toxin, inducing this patient....
Many institutions are evaluating their inpatient patterns of care for patients with diabetes mellitus and hyperglycemia, based upon compelling evidence that strict glycemic control improves outcomes in a variety hospital settings. In 2005, multidisciplinary task force was established at the University Kentucky Chandler Medical Center Lexington, Kentucky, to guide process improve quality safety inpatients hyperglycemia. This article describes stepwise including an examination our procedures,...
We recorded via telemetry the arterial blood pressure (BP) and heart rate (HR) response to classical conditioning following spontaneous onset of autoimmune diabetes in BBDP/Wor rats vs. age-matched, diabetes-resistant control (BBDR/Wor) rats. Our purpose was evaluate autonomic regulatory responses an acute stress a diabetic state up 12 months duration. The 15-s pulsed tone (CS+) followed by 0.5-s tail shock. initial, transient increase BP (i.e., "first component," or C(1)), known be derived...
The specificity and mechanisms through which HA alters basal PR1 release were evaluated. Rats bearing atrial catheters given icv infusions of histamine dihydrochloride or saline. Blood samples for PRL LH drawn before at 15, 30, 45, 60 min after infusion. Similar groups animals pretreated with diphenhydramine, cimetidine, atropine, methysergide prior to HA. Animals (90 μg) demonstrated least a twofold rise in 15 fell baseline levels 45 min. Pretreatment but not other agents, significantly...