A5013141329- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer, Lipids, and Metabolism
- Cardiac Health and Mental Health
- Lipoproteins and Cardiovascular Health
- Immune cells in cancer
- Immune Response and Inflammation
- RNA Research and Splicing
- Physical Activity and Health
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Protease and Inhibitor Mechanisms
- Extracellular vesicles in disease
Liaocheng People's Hospital
2017-2024
BACKGROUND: Non-small cell lung cancer (NSCLC) is the major subtype of cancer, imposing a huge disease burden worldwide. MicroRNA-1303 (miR-1303) has been demonstrated to be involved in several diseases, including cancers. In this study, we aimed investigate role miR-1303 NSCLC. M ETHODS: We quantified expression levels NSCLC tissues and cells using qRT-PCR assay. Then association between clinical characteristics patients was analyzed χ2 test. The Kaplan-Meier multivariate Cox regression...
Abstract Objective This study sought to examine the association between inactive time, leisure-time physical activity (LTPA), and mortality in individuals diagnosed with chronic obstructive pulmonary disease (COPD). Design utilized a nationally representative sample of patients COPD from National Health Nutrition Examination Survey (NHANES) survey (n = 1817; weighted population, 23,698,840). Mortality was tracked date interview examination. LTPA sedentary time were assessed using Global...
Introduction Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder marked by persistent respiratory symptoms and escalating airflow obstruction. The global rise in COPD incidence mortality poses significant societal burden. Despite its prevalence, the intricate pathogenesis of remains incompletely understood. This study aims to elucidate molecular markers potential therapeutic targets integrating known COPD-related genes analyzing RNA-Seq expression microarray data....
<title>Abstract</title> Chronic obstructive pulmonary disease (COPD) is a prevalent and progressive form of respiratory in which patients exhibit persistent damage affecting the alveoli and/or airway due to exposure toxic gases or particulate matter. The best-studied risk factor associated with COPD incidence cigarette smoke. C57BL/6 mice were exposed smoke lipopolysaccharide establish model, followed by scATAC sequencing scRNA lung tissue samples. resultant data revealed consistent findings...
MicroRNA is a class of short, single stranded, endogenous, non-coding RNA molecule that inhibits mRNA translation or directly degrades target by complementation with at post transcriptional levels.More than 1 000 kinds microRNA exist in the human genome, and regulate expression more 60% genes.Multiple studies have shown changes profiles chronic obstructive pulmonary disease (COPD) affect natural course pathophysiological process disease.Therefore, hot issue research COPD diagnosis...