A5084357763- Pharmaceutical Practices and Patient Outcomes
- Down syndrome and intellectual disability research
- Chronic Disease Management Strategies
- Genetics and Neurodevelopmental Disorders
- Frailty in Older Adults
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Genomics and Rare Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Schizophrenia research and treatment
- Pharmaceutical studies and practices
- Medication Adherence and Compliance
- Attention Deficit Hyperactivity Disorder
- Innovations in Medical Education
- Hip disorders and treatments
- Health Sciences Research and Education
- Autism Spectrum Disorder Research
- Immunodeficiency and Autoimmune Disorders
- Metabolism and Genetic Disorders
- Bipolar Disorder and Treatment
- Connective tissue disorders research
- Dementia and Cognitive Impairment Research
- Higher Education Learning Practices
- Intestinal Malrotation and Obstruction Disorders
- LGBTQ Health, Identity, and Policy
Monash University
2025
Trinity College Dublin
2015-2024
St. James's Hospital
2012
Robert Gordon University
2012
<h3>Objectives</h3> (1) To evaluate the prevalence of polypharmacy (5–9 medicines) and excessive (10+ (2) to determine associated demographic clinical characteristics in an ageing population with intellectual disabilities (IDs). <h3>Design</h3> Observational cross-sectional study. <h3>Setting</h3> Wave One (2009/2010) Intellectual Disability Supplement Irish Longitudinal Study on Ageing (IDS-TILDA). <h3>Participants</h3> A nationally representative sample 753 persons ID, aged between 41 90...
Background One-third to half of people with intellectual disabilities suffer from chronic constipation (defined as two or fewer bowel movements weekly taking regular laxatives three more times weekly), a cause significant morbidity and premature mortality. Research on risk factors associated is limited. Aims To enumerate in this population. Method A questionnaire was developed possible for constipation. The sent carers the case-loads four specialist disability services England. Data analysis...
Background No studies to date have investigated cumulative anticholinergic exposure and its effects in adults with intellectual disabilities. Aims To determine the anticholinergics factors associated high exposure. Method A modified Anticholinergic Cognitive Burden (ACB) scale score was calculated for a representative cohort of 736 people over 40 years old disabilities, associations demographic clinical assessed. Results Age 65 higher (ACB 1–4 odds ratio (OR) = 3.28, 95% CI 1.49–7.28, ACB 5+...
Abstract Background People with intellectual disability (ID) are at increased risk of exposure to psychotropic drugs and polypharmacy because the higher prevalence mental health conditions present more controversially, use these agents treat challenging behaviours. Despite fact that many adults ID exposed polypharmacy, few studies date have focused on patterns multiple psychotropics, or factors associated particularly in older population. This study aims examine prevalence, general...
The drug burden index (DBI) is a dose-related measure of anticholinergic and sedative exposure. This cross-sectional study described DBI in older adults with intellectual disabilities (ID) the most frequently reported therapeutic classes contributing to examined associations between higher scores potential adverse effects as well physical function.This analysed data from Wave 2 (2013/2014) Intellectual Disability Supplement Irish Longitudinal Study on Ageing (IDS-TILDA), representative...
Abstract Background Exposures to life events are associated with emotional, psychological and behavioural problems in those intellectual disability (ID). Older adults ID may experience different given differences living circumstances, cognitive decline, greater dependency on others less autonomy. This study examines the relationship of mental ill health an older population Ireland. Methods The was part ‘The Intellectual Disability Supplement Irish Longitudinal Study Ageing’. frequency...
Objectives Intellectual disability (ID) and epilepsy are independent risk factors for osteoporosis. Diverse predisposing influence this, example in ID, genetics poor nutrition epilepsy, anti-seizure medication (ASM). Around 25% people with ID have majority treatment resistant. ASMs polypharmacy is common. However, little known about the bone-related characteristics of this vulnerable group. A prospective observational cohort study bone profile across a community Epilepsy service was...
Background The frequent prescribing of psychotropics and high prevalence polypharmacy among older adults with intellectual disabilities require close monitoring. Aims To describe change in prevalence, predictors health outcomes psychotropic use during the four waves (2009/2010, 2013/2014, 2016/2017, 2019/2020) Intellectual Disability Supplement to Irish Longitudinal Study on Ageing (IDS-TILDA). Method Eligible participants were (≥40 years) who participated all IDS-TILDA reported medication...
Abstract There are limited studies on the prevalence of epilepsy and co-morbid conditions in older adults with an ID. To begin to address this was estimated for participants Intellectual Disability Supplement Irish Longitudinal Study Ageing. Associations demographic variables co morbid health were examined. It found that high (30.7%); but declined as people aged. Those less likely live family, independently or community settings, rates refractory and, despite medication over half those still...
Understanding the medication and supplement use of aging people is critical to ensuring that health service providers in primary care can optimise these agents. An increasing number with different levels intellectual disability (ID) are living community becoming for first time substantial users services. This, however, brings new challenges need be addressed at level. We quantified medicines food supplements described associated patterns morbidity two comparable cohorts population without...
Background: To describe a research skills curriculum across the five years of Master’s in Pharmacy (MPharm) programme whereby students designed, undertook, and disseminated Practice (PoP) projects. Methods: In 1 to 3, developed basic through workshops academic writing, critical appraisal, presentation, database searching, information gathering. The training received by was comprehensive journey from learning theoretical principles idea generation, planning, application, execution,...
Abstract Background There are concerns that antipsychotics may be used inappropriately in adults with intellectual disability for problem behaviours the absence of a diagnosed mental health condition. The aim was to examine prevalence and patterns antipsychotic use their association conditions older disability. Methods Cross‐sectional data were drawn from Wave 2 (2013/2014) Intellectual Disability Supplement Irish Longitudinal Study on Ageing ( IDS ‐ TILDA ). Medication available 95.6% n =...
(1) To investigate the prevalence of osteopenia and osteoporosis among adults with intellectual disabilities (IDs) (2) to examine alternative optimal bone screening techniques. Observational cross-sectional study. Wave 2 (2013-2106) Intellectual Disability Supplement Irish Longitudinal Study on Ageing. A national representative sample 604 male female persons ID aged 43 years over. In total, 575 participants completed quantitative ultrasound (QUS) measurements for one or both feet....
Abstract Purpose Recently, efforts have been made to quantify frailty among older adults with intellectual disability (ID). Medication exposure is associated without ID. However, there little research on this association The aim of study was examine specifically in people ID the between and medication exposure, including anticholinergic sedative exposure. Methods Data were drawn from Wave 2 (2013/2014) Intellectual Disability Supplement Irish Longitudinal Study Ageing (IDS‐TILDA), a...
The prevalence of epilepsy is higher in people with intellectual disability (ID) and increases the degree ID. Although life expectancy for ID increasing, coexisting have a mortality rate, particularly those who had recent seizures. There been few observational studies patterns anti-epileptic prescribing among older epilepsy. aim this study was to investigate treatment representative population epilepsy.This an cross-sectional from wave 1 (2009/2010) Intellectual Disability Supplement Irish...
Drug Burden Index (DBI), a measure of exposure to medications with anticholinergic and sedative activity, has been associated poorer physical function in older adults the general population. While extensive study conducted on associations between DBI population, little is known about intellectual disabilities (ID). This first which aims examine association score its two sub-scores, burden, objective measures performance, grip strength timed up go, dependency, Barthel activities daily living,...
This paper describes the design and implementation of elements an integrated competency-focused pharmacy programme in School Pharmacy Pharmaceutical Sciences (SoPPS), Trinity College Dublin (TCD), Ireland. Following a national review education training Ireland 2010, subsequent publication legislation 2014, has implemented five-year training, leading to award Master's degree (M. Pharm.). Curricular integration been achieved by underpinning new with competency framework for pharmacists through...
Antiepileptic drugs (AEDs) may affect mood and behavior in people with epilepsy intellectual disability. A high AED load, derived from polytherapy and/or doses of AEDs, has been suggested to be a risk factor for behavioral side effects. Data were drawn Wave 3 the Intellectual Disability Supplement Irish Longitudinal Study on Ageing (IDS-TILDA). The Behavior Problems Inventory Short Form (BPI-S) was used assess challenging behaviors. load calculated median loads obtained. Non-parametric tests...