A5007306447- Down syndrome and intellectual disability research
- Chronic Disease Management Strategies
- Frailty in Older Adults
- Dementia and Cognitive Impairment Research
- Healthcare innovation and challenges
- Family and Disability Support Research
- Retirement, Disability, and Employment
- Functional Brain Connectivity Studies
- Health disparities and outcomes
- Elder Abuse and Neglect
- Cerebral Palsy and Movement Disorders
- Family Caregiving in Mental Illness
- Advanced MRI Techniques and Applications
- Dental Health and Care Utilization
- Aging, Health, and Disability
- Intergenerational Family Dynamics and Caregiving
- COVID-19 and healthcare impacts
- Healthcare Decision-Making and Restraints
- Global Health Care Issues
- Aging and Gerontology Research
- Adolescent and Pediatric Healthcare
- Health, Environment, Cognitive Aging
- Patient Dignity and Privacy
- Genetics and Neurodevelopmental Disorders
- Substance Abuse Treatment and Outcomes
Trinity College Dublin
2014-2025
University Memory and Aging Center
2025
University of California, San Francisco
2023-2025
Trinity College
2023-2024
Global Brain Health Institute
2020-2024
Tallaght University Hospital
2022
Louisiana State University
2019
People with Down syndrome (DS) have high risk of developing Alzheimer's disease (AD). This study examined mean ages AD diagnosis and associations co-occurring conditions among adults DS from five European countries.
Abstract INTRODUCTION The Cambridge Cognitive Examination modified for use in people with Down syndrome (CAMCOG‐DS) is a sensitive cognitive test Alzheimer's disease (AD)–related decline DS, but needs updates sensitivity, cultural adaptability, and additional memory/executive function items. This study aimed to develop validate the CAMCOG‐DS‐II. METHODS In this multi‐language, multi‐site study, psychometric properties of CAMCOG‐DS‐II were evaluated against previously validated measures 223...
Background The benefits of being in employment are well documented; however, underemployment is a critical issue for people with intellectual disability ( ID ). Some individuals perceive themselves as when fact they attending non‐work site such day service. impact that this perception has on other areas life not been investigated and research into area could have implications both policy makers service providers. Materials Methods first wave the Supplement to Irish Longitudinal Study Ageing...
Abstract Objectives The objectives of this study were to describe the reported dentate status and complete denture use older people with intellectual disability ( ID ) compare those in general population I reland. Methods first wave ntellectual D isability S upplement T he rish L ongitudinal tudy on A geing IDS ‐ TILDA provides opportunity measure edentulism a nationally representative sample Data drawn from matched using propensity score matching data ), among adults All variables showing...
Abstract There are limited studies on the prevalence of epilepsy and co-morbid conditions in older adults with an ID. To begin to address this was estimated for participants Intellectual Disability Supplement Irish Longitudinal Study Ageing. Associations demographic variables co morbid health were examined. It found that high (30.7%); but declined as people aged. Those less likely live family, independently or community settings, rates refractory and, despite medication over half those still...
Cognitive reserve supports cognitive function in the presence of pathology or atrophy. Functional neuroimaging may enable direct and accurate measurement which could have considerable clinical potential. The present study aimed to develop validate a measure using task-based fMRI data that then be applied independent resting-state data. Connectome-based predictive modelling with leave-one-out cross-validation was predict residual functional connectivity from Reserve/Reference Ability Neural...
Longitudinal study of people with intellectual disability and other difficult to reach populations requires specific recruitment retention strategies be successful.This paper provides a case participant for longitudinal ageing among older adults in Ireland.Development implementation recruit retain participants aged 40+ years, comprising four data collection waves over more than decade, are reported. Recruitment outcomes assessed alongside factors successful implementation.A nationally...
Carers supporting people with an intellectual disability often rely on others to manage the burden of care. This research aims compare differences between carer groups and understand predictors loneliness changes for carers disability. Data from international CLIC study were analysed. In total, 3930 responded four groups; who care those mental health difficulties (
Abstract The Intellectual Disability Supplement to Irish Longitudinal Study on Ageing is a national longitudinal study the aging of people with an intellectual disability (ID) using randomly selected sample ID over age 40. In total, 367 completed perception self-report only section. Over 57% described their health as very good excellent no significant difference in perceptions found for gender, level ID, or living circumstance. Exploring people's utilizing PASW Text Analytics Surveys 4.1...
While higher rates and earlier onset of frailty have been reported among adults with intellectual developmental disabilities (IDD), research on how best to support these individuals is lacking.An international consultation relied three consensus building methods: the Nominal Group Technique, an NIH conference approach, a Delphi survey.There agreement that person-centered planning aging in place should be guiding principles. Frailty must considered than general population recognition...
Abstract Background Individuals with Down syndrome (DS) are at much greater risk of developing Alzheimer's disease, and one the early clinical symptoms disease is executive dysfunction. In general population, cognitive training has shown some promising results in relation to maintaining or improving processes. There currently a gap literature for adults DS. Methods A quasi‐experimental mixed factorial design partial crossover was used involving an 8‐week intervention period using brain...
To investigate dental attendance patterns and reasons for nonattendance among older adults with intellectual disabilities (ID) in Ireland. A cross-sectional survey of quantitative data text analysis qualitative drawn from a nationally representative sample 753 people ID over 40 years age Participants were considered as regular or irregular attenders data. Text grouped open-ended responses analysis. There slightly more females. Mean was 54.1 (SD = 8.8). Almost half had moderate ID. majority...
Key Points Dementia risk is elevated in people with intellectual disability, particularly for those Down syndrome Differences lifestyle factors have been cited as that exacerbate dementia disability Lifestyle can be targeted to enhance cognitive reserve and reduce