A5101837305- Oral microbiology and periodontitis research
- Gut microbiota and health
- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Genomics and Phylogenetic Studies
- Gastrointestinal motility and disorders
- Nanoparticle-Based Drug Delivery
- Polysaccharides and Plant Cell Walls
- Plant Molecular Biology Research
- Clostridium difficile and Clostridium perfringens research
- Legume Nitrogen Fixing Symbiosis
- Phytochemical compounds biological activities
- Phytochemistry and Bioactive Compounds
- Cancer Mechanisms and Therapy
- Software Testing and Debugging Techniques
- Soybean genetics and cultivation
- Oral Health Pathology and Treatment
- Natural Compound Pharmacology Studies
- Bacterial biofilms and quorum sensing
- Software Engineering Research
- Advanced Malware Detection Techniques
- HIV/AIDS oral health manifestations
- Infant Nutrition and Health
- Salivary Gland Disorders and Functions
- Antimicrobial Peptides and Activities
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Guang’anmen Hospital
2023-2024
Dairy Management
2022-2023
Inner Mongolia Yili Industrial Group (China)
2022-2023
South China Agricultural University
2023
Globally, dental caries is one of the most common non-communicable diseases for patients all ages; Streptococcus mutans (S. mutans) its principal pathogen. Lactobacillus paracasei (L. paracasei) shows excellent anti-pathogens and immune-regulation functions in host. The aim this study to evaluate effects L. ET-22 on formation S. biofilms. living bacteria, heat-killed secretions were prepared using same number bacteria. In vitro, they added into artificial-saliva medium, used coculture with...
Oral microbial dysbiosis is the primary etiologic factor for halitosis and may be critical preventive target halitosis. This study included randomized controlled trials (RCTs) assessing effects of Lactobacillus paracasei ET-22 live heat-killed bacteria on related oral microbiome. 68 subjects were divided into placebo, (ET-22.L) (ET-22.HK) groups. Subjects took different lozenges three times a day 4 weeks underwent saliva collection assessment breath volatile sulfur compound (VSC) levels at...
Probiotics have aroused increasing concern as an intervention strategy for periodontitis (PD), but their underlying mechanism of action remains poorly characterized. Regarding the significance oral microbiota dysbiosis related to PD, we predicted that preventive activity probiotics may be influenced by suppressing bacterial pathogenicity. Herein, investigated effects Lactobacillus paracasei L9 (L9) and Bifidobacterium animalis A6 (A6) on PD using a rat model, demonstrated regulatory effect...
It is feasible by gavage live and heat-killed bifidobacterium animalis J-12 to intervene in oral ulcers caused methyl viologen dichloride modeling.
The SPIRAL1 (SPR1) gene family encodes microtubule-associated proteins that are essential for the anisotropic growth of plant cells and abiotic stress resistance. Currently, little is known about characteristics roles outside Arabidopsis thaliana. This study intended to investigate SPR1 in legumes. In contrast A. thaliana, has undergone shrinking model legume species Medicago truncatula Glycine max. While orthologues were lost, very few SPR1-Like (SP1L) genes identified given genome size two...
Abstract Background Current treatment for functional dyspepsia (FD) has limited and unsustainable efficacy. Probiotics have the potential to alleviate FD; However, underlying mechanism remains unclear. This study aimed evaluate effect of probiotics in alleviating FD. Methods A randomized, positive-drug placebo-controlled clinical trial was conducted; 200 FD patients were randomly divided into four groups (placebo, positive control [proton pump inhibitors, PPI] or Bifidobacterium lactis BL-99...
Abstract Live and heat-killed Bifidobacterium has been proven to have anti-inflammatory antioxidant effects. In this study, we evaluated the effects of live animalis J-12 (J-12) on oral ulceration LVG golden Syrian hamsters after buccal membrane injection with methyl viologen dichloride. Results showed that interleukin-1β, glutathione malondialdehyde in serum, downregulated by gavage bacteria. The bacteria can reduce expression matrix metalloproteinase-9 reducing nuclear factor kappa-B, thus...
Background: Current treatment for functional dyspepsia (FD) has limited and unsustainable efficacy. Probiotics have the potential to alleviate FD; However, underlying mechanism remains unclear. This study aimed evaluate effect of probiotics in alleviating FD.Methods: A randomized, positive-drug, placebo-controlled clinical trial was conducted at Beijing Chaoyang Hospital, Capital Medical University; Patients with FD (18-60 years, defined according Rome IV criteria) were randomly divided into...