A5102751418- Environmental Toxicology and Ecotoxicology
- Glutathione Transferases and Polymorphisms
- Genomics, phytochemicals, and oxidative stress
- Toxic Organic Pollutants Impact
- Pharmaceutical and Antibiotic Environmental Impacts
- Pharmacogenetics and Drug Metabolism
- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Effects and risks of endocrine disrupting chemicals
- Pesticide Exposure and Toxicity
- Carcinogens and Genotoxicity Assessment
- Olfactory and Sensory Function Studies
- Reproductive biology and impacts on aquatic species
- Physiological and biochemical adaptations
- Zebrafish Biomedical Research Applications
- Marine animal studies overview
- Acute Lymphoblastic Leukemia research
- Ocean Acidification Effects and Responses
- Mercury impact and mitigation studies
- Computational Drug Discovery Methods
- Mycotoxins in Agriculture and Food
- Chemistry and Chemical Engineering
- Fish Ecology and Management Studies
- Estrogen and related hormone effects
- Isotope Analysis in Ecology
University of Washington
2011-2020
Theodore Roosevelt High School
1996-2019
University of Occupational and Environmental Health Japan
2015
Seattle University
2006
University of Florida
1998-2004
Duke University
1988-1993
Previous studies have suggested that there may be species-specific differences in the metabolism of polybrominated diphenyl ethers (PBDEs) among different fish species. In this study, we investigated vitro hepatic eleven individual PBDE congeners (tri- through decaBDEs) three species: rainbow trout (Oncorhynchus mykiss), common carp (Cyprinus carpio), and Chinook salmon (O. tschwatcha). addition, evaluated influence structural characteristics (i.e., bromine substitution patterns) on...
Abstract Elevated concentrations of CO 2 in seawater can disrupt numerous sensory systems marine fish. This is particular concern for Pacific salmon because they rely on olfaction during all aspects their life including homing migrations from the ocean back to natal streams. We investigated effects elevated coho ( Oncorhynchus kisutch ) olfactory‐mediated behavior, neural signaling, and gene expression within peripheral central olfactory system. Ocean‐phase were exposed three levels ,...
The polybrominated diphenyl ethers (PBDEs) are a group of flame retardants whose residues have markedly increased in the environment and human tissues during last decade. Of various congeners, BDE 47 (2,2′,4,4′-tetrabromodiphenyl ether) is typically predominant congener observed fish wildlife samples, as well tissues. Several studies indicate utero transfer PBDEs pregnancy with accumulating fetal tissues, thus potential for 47–mediated injury concern. In this study, we examined mechanisms to...
Metals such as copper disrupt olfactory function in fish. Unfortunately, little is understood of the molecular consequences impairment, thus hindering development relevant diagnostic tools injury. To address this critical data gap, we analyzed gene expression within tissues adult zebrafish exposed to CuCl2 (6, 16, 40 ppb) for 24 h. Transcriptional markers impairment entire system were identified and specific genes interest (e.g., S100a, parvalbumin 8, marker protein, calbindin 2-like...
Although environmental trace metals, such as copper (Cu), can disrupt normal olfactory function in fish, the underlying molecular mechanisms of metal-induced injury have not been elucidated. Current research has suggested involvement epigenetic modifications. To address this hypothesis, we analyzed microRNA (miRNA) profiles system Cu-exposed zebrafish. Our data revealed 2, 10, and 28 differentially expressed miRNAs a dose–response manner corresponding to three increasing Cu concentrations....
Green chemistry can strongly attract students to chemistry. We, therefore, developed a green educational game that motivates at the undergraduate and advanced high school levels consider sustainability concerns as they design hypothetical, chemical product. The is intended for incorporation into any course majors non-majors teaches and/or Principles of Chemistry level. free charge encourages think like professional designers develop product with respect function improved human environmental...