A5028808822- Magnetic Properties of Alloys
- Metallic Glasses and Amorphous Alloys
- Material Dynamics and Properties
- Magnetic and transport properties of perovskites and related materials
- Thermodynamic properties of mixtures
- Graphene research and applications
- Shape Memory Alloy Transformations
- Carbon Nanotubes in Composites
- Drug Solubulity and Delivery Systems
- Liquid Crystal Research Advancements
- Crystallization and Solubility Studies
- Rare-earth and actinide compounds
- Microencapsulation and Drying Processes
- Diamond and Carbon-based Materials Research
- Magnetic Properties and Synthesis of Ferrites
- Ionic liquids properties and applications
- Thermal and Kinetic Analysis
- Energetic Materials and Combustion
- High Entropy Alloys Studies
- Electromagnetic wave absorption materials
- Boron and Carbon Nanomaterials Research
- High-pressure geophysics and materials
- Advancements in Battery Materials
- Heusler alloys: electronic and magnetic properties
- Supercapacitor Materials and Fabrication
Łukasiewicz Research Network
2019-2024
Łukasiewicz Research Network - Institute of Non-Ferrous Metals
2015-2024
Tele & Radio Research Institute
2018
Paul Scherrer Institute
2018
University of Silesia in Katowice
2005-2015
Institute of Physics
2005-2015
Silesian Center for Heart Disease
2014-2015
Institute for Chemical and Physical Processes
2012
Leibniz Institute of Polymer Research
2011
University of Kent
2008
Abstract The new (Zn,Mg,Ni,Fe,Cd)Fe 2 O 4 high entropy ferrite with average crystallite size 11.8 nm was synthesized in two stages by annealing of co-precipitated amorphous precursor. dielectric spectroscopy confirms, that the electrical conductivity and polarization processes are associated mobility electrons structure ferrite. It concluded, both, frequency complex permittivity as well magnetic permeability strongly temperature dependent. AC is quantum mechanical tunneling related to...
By using dielectric spectroscopy we analyzed the relation between molecular mobility and tendency of amorphous celecoxib to recrystallize. We found that is kinetically a fragile glassformer, contrary conclusion reached by others from thermodynamic fragility. The possible correlation large crystallize with various motions have been investigated. Our study shows structural relaxation seems be responsible for devitrification if stored at room temperature ∼293 K. Notwithstanding, crystallization...
Dielectric spectroscopy (DS) was used to investigate the relaxation dynamics of supercooled and glassy ibuprofen at various isobaric isothermal conditions (pressure up 1750 MPa). The ambient pressure data are in good agreement with that reported previously literature. Our high measurements revealed validity temperature−pressure superpositioning (TPS) for α-peak. We also found value fragility index decreases compression from m = 87 ± 2 atmospheric 72.5 3.5 (p 920 drop observed our experiment...
Glibenclamide (GCM) is an oral hypoglycemic agent of the sulfonylurea group used in treatment non-insulin-dependent diabetes. Crystalline GCM characterized by low bioavailability, which attributed to its poor dissolution properties. It prompted us prepare this drug amorphous form as a means enhance characteristics. Two different methods were convert crystalline into glassy form: quench-cooling melt and cryogenic milling. To monitor solid-state properties samples, X-ray powder diffraction...
Comprehensive molecular dynamics studies of vitrified and cryogrounded itraconazole (Itr) were performed at ambient elevated pressure. DSC measurements yielded besides melting glass transition observed during heating cooling both samples two further endothermic events around T = 363 K 346 K. The nature these transitions was investigated using X-ray diffraction, broadband dielectric spectroscopy Density Functional Theory calculations. indicated that extra ordering in is likely to occur. Based...
In this paper, the physical stability and molecular dynamics of amorphous sildenafil are investigated in both liquid glassy states. We have established that is resistant to recrystallization at temperatures below glass transition temperature Tg during experimental period its storage (i.e., above 6 months), however, it easily undergoes cold crystallization T > Tg. To determine mechanism, isothermal non-isothermal studies kinetics drug performed by using broadband dielectric spectroscopy (BDS)...
In this paper, we present a novel way of stabilization amorphous celecoxib (CEL) against recrystallization by preparing binary celecoxib-octaacetylmaltose (CEL-acMAL) systems quench-cooling the molten phase. As far as know is first application carbohydrate derivatives with acetate groups to enhance stability an drug. We found that CEL in mixture acMAL characterized much better solubility than pure CEL. report very promising results long-term measurements CEL-acMAL system small amount...
This study for the first time investigates physicochemical properties of amorphous indapamide drug (IND), which is a known diuretic agent commonly used in treatment hypertension. The solid-state vitrified, cryomilled and ball-milled IND samples were analyzed using X-ray powder diffraction (XRD), mass spectrometry, nuclear magnetic resonance (NMR), infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC) broadband dielectric (BDS). These analytical techniques enabled us (i) to...
The purpose of this paper is to examine the role molecular mobility in recrystallization process from amorphous state anticholesterol drug ezetimibe. Both dynamics and crystallization kinetics have been studied using various experimental techniques, such as broadband dielectric spectroscopy (BDS), differential scanning calorimetry (DSC), X-ray diffraction (XRD). Our investigations shown that ezetimibe easily recrystallizes disordered state, both below above its glass transition temperature...
There are a number of chemical compounds that readily convert to other isomers when their crystalline structure is lost (e.g., during melting or dissolution). This phenomenon, commonly known as tautomerism, subject intense research. It an important problem especially in pharmaceutical industry because various drug may have different pharmacological activity. Therefore, it find appropriate experimental technique which enables the determination isomerization ability compounds. In this...
In this paper the molecular dynamics of a common local-anesthetic drug, lidocaine hydrochloride (LD-HCl), and its water mixtures were investigated. By means broadband dielectric spectroscopy calorimetric measurements it was shown that even small addition causes significant effect on relaxation analyzed protic ionic liquid. Apart from two well-resolved relaxations (σ- γ-processes) β-mode, identified as JG-process, observed for anhydrous LD-HCl, new peak (υ) is visible in spectra aqueous drug....
To investigate the effect of cryogrinding on chemical stability diuretic agent furosemide and its mixtures with selected excipients.Furosemide was ground at liquid nitrogen temperature for 30, 60, 120 180 min. Mixtures furosemide-PVP furosemide-inulin (1:1) were milled under cryogenic conditions. Materials analyzed by XRD, UPLC, MS NMR.Upon increasing milling time, a significant build-up an unidentified impurity 1, probably main degradation product, noticed. Cogrinding PVP inulin worsened...
High-entropy ferrites (HEFs) are a new group of high-entropy oxides with unique magnetodielectric properties that offer wide array possibilities for high-frequency applications. Various ions were introduced at octahedral sites in the spinel structure to test role structure's formation on its properties. The structural analysis confirmed single-phase even (FeCoNiMg)(FeCr)2O4 HEF. Dielectric studies showed introducing Mg2+ and Cr3+ increased electrical conductivity dielectric losses over...