Lunga Mfingwana

ORCID: 0000-0002-1265-8892
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About
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Research Areas
  • Tracheal and airway disorders
  • Congenital Diaphragmatic Hernia Studies
  • Amoebic Infections and Treatments
  • Esophageal and GI Pathology
  • Congenital Anomalies and Fetal Surgery
  • Parasitic infections in humans and animals
  • Foreign Body Medical Cases
  • Immunodeficiency and Autoimmune Disorders
  • Tuberculosis Research and Epidemiology
  • Actinomycetales infections and treatment
  • Infectious Diseases and Tuberculosis
  • Airway Management and Intubation Techniques
  • Head and Neck Anomalies
  • Hematological disorders and diagnostics
  • Neonatal Health and Biochemistry
  • Parvovirus B19 Infection Studies
  • Gastrointestinal disorders and treatments
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Restraint-Related Deaths
  • Inhalation and Respiratory Drug Delivery
  • Immune responses and vaccinations
  • Neonatal and fetal brain pathology
  • Respiratory Support and Mechanisms
  • Mycobacterium research and diagnosis
  • Cytomegalovirus and herpesvirus research

University of Pretoria
2024

Steve Biko Hospital
2024

Stellenbosch University
2019-2023

Tygerberg Hospital
2019-2023

Western Cape Department of Health
2020-2021

National Health Laboratory Service
2021

The coronavirus disease-2019 (COVID-19) era is a challenging time for respiratory teams to protect their patients and staff. COVID-19 predominantly transmitted by droplets; in the clinical setting, aerosol generating procedures pose greatest risk transmission. Bronchoscopy associated with increased of patient-to-health care worker transmission, owing aerosolized viral particles which may be inhaled also result environmental contamination surfaces.

10.1002/ppul.25015 article EN Pediatric Pulmonology 2020-08-07

Echinococcus granulosus is a major public health problem in lower middle-income countries (LMIC). Children are commonly diagnosed with cysts the lungs and/or liver.The purpose of this study was to describe pediatric cohort pulmonary Cystic (CE) and treated combination medical surgical therapy.This retrospective performed between July 2017 December 2020 at Tygerberg Hospital, South Africa. Clinical, laboratory, radiological, medical, surgery-related outcomes were reviewed.The consisted 35...

10.1002/ppul.25854 article EN Pediatric Pulmonology 2022-02-05

The secondary injury may present weeks to months after the initial insult and repeat bronchoscopy, long-term follow-up is required for respiratory complications of CSI.Ingestion caustic fluid cause severe tracheal stenosis. Repeated airway dilatation be a lifesaving intervention until such point that surgery can performed.

10.1002/ccr3.2395 article EN cc-by Clinical Case Reports 2019-09-11

Bronchoscopy can be a useful tool in children with pulmonary tuberculosis (PTB) severe disease potentially requiring intervention or the face of diagnostic dilemmas. The aim this study was to determine value Xpert MTB/RIF assay (Xpert) on bronchoalveolar lavage (BAL) samples complicated PTB.Retrospective analysis clinically diagnosed PTB, who underwent routine bronchoscopy over 5-year period at large referral hospital. BAL and other respiratory were tested by microscopy, culture, Xpert. We...

10.1002/ppul.25405 article EN Pediatric Pulmonology 2021-04-05

Abstract Introduction Broncho‐esophageal fistula (BOF) is a rare complication of Mycobacterium tuberculosis (MTB). TB‐associated BOF presents either as acute respiratory failure, aspiration pneumonia or surgical decompression thoracic lymph nodes. Methods All children with TB‐ associated were included. TB was diagnosed if MTB cultured from secretions, Ziehl‐Neelsen (ZN) smear positive, GeneXpert MTB/RIF positive chest radiograph revealed radiographic features typical TB. by contrast swallow...

10.1002/ppul.24775 article EN Pediatric Pulmonology 2020-04-10

BACKGROUND: Children under 1 year of age with hypoxic pneumonia regularly have concurrent cytomegalovirus (CMV) viremia. In these children, the diagnosis CMV-associated and prediction an outcome are difficult. It is unclear whether quantification blood CMV viral load (CMV-VL) can predict outcomes in children. METHODS: This was a retrospective study including children (1–12 months age), detectable CMV-VL admitted to paediatric intensive care unit Tygerberg Hospital, Cape Town, South Africa...

10.5588/ijtld.22.0428 article EN The International Journal of Tuberculosis and Lung Disease 2023-01-01

Abstract Most foreign bodies are located in the central airways and can be reached removed with either a flexible or rigid bronchoscope combination of two methods. The removal more distal present significant challenge. We describe case an 11‐year‐old child, who aspirated sewing needle that lodged subsegment medial segment right lower lobe. As result, it was visible only 2.8 mm (FOB). Mono‐planar fluoroscopic guidance useful for confirming placement allowing biopsy forceps to grasp move...

10.1002/ppul.24653 article EN Pediatric Pulmonology 2020-01-15

Actinomycosis is a rare, indolent and invasive infection caused by Actinomyces species. Pulmonary actinomycosis very rarely seen in the paediatric population. The classic radiological presentation of thoracic involvement includes lower lobe consolidation, empyema periostitis ribs. We report case endobronchial child diagnosed on biopsy bronchoalveolar lavage (BAL). Bronchoscopy can be dangerous when performed these cases, as there risk severe bleeding large airway obstruction, was with this patient.

10.1002/ppul.25550 article EN Pediatric Pulmonology 2021-07-15

Horseshoe lung is a very rare congenital malformation in which the bases of right and left are fused to each other by narrow isthmus. Although rare, hyperlucent area lower lung, close vertebral column, may represent horseshoe lung. often associated with scimitar syndrome. Here, we present case 2-year-old girl who presented recurrent chest infections wheezing The appeared be hypoplastic.

10.7196/ajtccm.2021.v27i4.138 article EN cc-by-nc African Journal of Thoracic and Critical Care Medicine 2021-12-31

Echinococcus granulosus (CE) is a worldwide public health problem causing considerable human morbidity and mortality. We report on case of complicated paediatric echinococcosis as evidenced by pulmonary, hepatic cardiac cysts. Combined surgery chemotherapy represent an appropriate strategy for managing cardiopulmonary echinococcosis. However, there pressing need developing prevention strategy, collaborative research efforts establishing registry information sharing, particularly in SA other...

10.7196/sajch.2024.v18i2.1851 article EN cc-by-nc South African Journal of Child Health 2024-07-12

A 10-year-old boy presented with minimal haemoptysis after 1 week of cough and fever. He had a similar presentation 3 years earlier; the diagnosis at that stage was right lower lobe pneumonia. is HIV uninfected has no known tuberculosis exposure. Investigations revealed raised white cell

10.1136/bcr-2020-238796 article EN BMJ Case Reports 2020-10-01

A 13-week-old female infant presented to a tertiary hospital with 5-day history of coughing, feeding difficulty, vomiting and tachypnoea. She was previousy well, her weight plots followed the median weight-for-age Z score immunisation record up date. No antenatal ultrasound

10.1136/bcr-2021-242037 article EN BMJ Case Reports 2021-03-01

Background. Neonatal hypoxic ischaemic encephalopathy (HIE) is a leading cause of term neonatal death worldwide, with higherincidence in low- to middle-income settings.Objective. To investigate whether nucleated red blood cell (nRBC) counts could predict severity HIE and outcomes neonatestreated therapeutic hypothermia (TH).Methods. We conducted retrospective sub-study at Tygerberg Hospital Cape Town, South Africa. The review included all cooledneonates’ clinical records samples from...

10.7196/sajch.2023.v17i3.1969 article EN cc-by-nc South African Journal of Child Health 2023-10-19

A 1-year 5-month-old boy presents with a 1-day history of severe biphasic stridor. He had multiple previous admissions for recurrent lower respiratory tract infections. On his last admission, month earlier, he was seen noisy breathing, where laryngomalacia suspected and confirmed on non-

10.1136/bcr-2020-241133 article EN BMJ Case Reports 2021-01-01

Actinomycosis is a rare, indolent and invasive infection caused by Actinomyces species. Pulmonary actinomycosis very rarely seen in the paediatric population. The classic radiological presentation of thoracic involvement includes lower lobe consolidation, empyema periostitis ribs. We report case endobronchial pulmonary child diagnosed on biopsy broncho-alveolar lavage taken during bronchoscopy. Bronchoscopy can be dangerous when performed these cases, as there risk severe bleeding large...

10.22541/au.162045853.33619523/v1 preprint EN cc-by Authorea (Authorea) 2021-05-08
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