A5073515899- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- Wheat and Barley Genetics and Pathology
- Plant Disease Resistance and Genetics
- Plant and fungal interactions
- Carcinogens and Genotoxicity Assessment
- Indoor Air Quality and Microbial Exposure
- Pesticide Residue Analysis and Safety
- Analytical Chemistry and Chromatography
- Agriculture, Plant Science, Crop Management
- Insect and Pesticide Research
- GABA and Rice Research
- Metabolism and Genetic Disorders
- Mass Spectrometry Techniques and Applications
- Fungal Biology and Applications
- Folate and B Vitamins Research
- Plant Pathogens and Resistance
- Seed and Plant Biochemistry
- Potato Plant Research
- Amino Acid Enzymes and Metabolism
- Listeria monocytogenes in Food Safety
- Essential Oils and Antimicrobial Activity
- Agricultural safety and regulations
- Plant Toxicity and Pharmacological Properties
- Genetically Modified Organisms Research
Cape Peninsula University of Technology
2014-2021
Stellenbosch University
1984-2014
South African Medical Research Council
2004-2013
Tygerberg Hospital
1984-2013
Medical Research Council
2001-2013
Centre international de recherche sur le cancer
2011
University of Leeds
2011
University of Pretoria
2003-2007
University of South Africa
2006
Hamedan University of Medical Sciences
2006
Consecutive outbreaks of acute aflatoxicosis in Kenya 2004 and 2005 caused > 150 deaths. In response, the Centers for Disease Control Prevention World Health Organization convened a workgroup international experts health officials Geneva, Switzerland, July 2005. After discussions concerning what is known about aflatoxins, identified gaps current knowledge chronic human effects surveillance food monitoring, analytic methods, efficacy intervention strategies. The also public strategies that...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNatural occurrence of some Fusarium mycotoxins in corn from low and high esophageal cancer prevalence areas the Transkei, Southern AfricaEric W. Sydenham, Pieter G. Thiel, Walter F. O. Marasas, Gordon S. Shephard, Dirk J. Van Schalkwyk, Klaus R. KochCite this: Agric. Food Chem. 1990, 38, 10, 1900–1903Publication Date (Print):October 1, 1990Publication History Published online1 May 2002Published inissue 1 October...
Abstract A high-performance liquid chromatographic method has been developed for the quantitative determination of recently described mycotoxins, fumonisins B1 (FB1) and B2 (FB2) utilizing pre-column derivatization with o-phthaldialdehyde, isocratic elution, fluorescence detection. Prior to analysis, sample extracts were purified on strong anion exchange cartridges. The applied analysis naturally contaminated corn mixed horse feed samples as well fungal culture material, presence mycotoxins....
As part of a comprehensive risk assessment study for fumonisins, reliable data on exposure populations to these dietary toxins must be obtained. To assess the extent worldwide exposure, published literature contamination food and feed supplies has been reviewed supplemented with unpublished material from various international sources. Fumonisin corn corn-based products occurs in many countries. Animal mycotoxicoses such as equine leukoencephalomalacia porcine pulmonary edema are caused by...
Adverse human health effects from the consumption of mycotoxins have occurred for many centuries. Although mycotoxin contamination agricultural products still occurs in developed world, application modern practices and presence a legislatively regulated food processing marketing system greatly reduced exposure these populations. At levels generally found traded market economies, adverse largely been overcome. However, developing where climatic crop storage conditions are frequently conducive...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFumonisin contamination of commercial corn-based human foodstuffsEric W. Sydenham, Gordon S. Shephard, Pieter G. Thiel, Walter F. O. Marasas, and Sonja StockenstromCite this: J. Agric. Food Chem. 1991, 39, 11, 2014–2018Publication Date (Print):November 1, 1991Publication History Published online1 May 2002Published inissue 1 November 1991https://pubs.acs.org/doi/10.1021/jf00011a028https://doi.org/10.1021/jf00011a028research-articleACS...
Aflatoxins are secondary metabolites of the fungi Aspergillus flavus and A. parasiticus, occur widely on many staple foods cause a broad range detrimental health effects in animals humans. As consequence, maximum tolerated levels (MTLs) have been legislated countries. However, developing countries where food safety compliance can be low significant supply locally consumed by producers or purchased at local markets, more comprehensive strategies required. In this regard, risk analysis with...
Fumonisins B1 (FB1) and B2 (FB2), two structurally related mycotoxins with cancer-promoting activity, were recently isolated from corn cultures of Fusarium moniliforme MRC 826. These toxins have been reported to be produced also by isolates F. proliferatum. Contamination foods feeds has associated human esophageal cancer risk, FB1 shown the causative agent neurotoxic disease leukoencephalomalacia in horses. Because toxicological importance fumonisins, potential produce FB2 was determined a...
Traditional and improved varieties of maize, pearl millet sorghum were planted by small-scale farmers under the direction International Institute for Tropical Agriculture in two Nigerian agro-ecological zones: Sudan Savanna Northern Guinea Savanna. Samples collected determination Fusarium infection fumonisin (B1, B2 B3) contamination. A previous paper reported Aspergillus aflatoxin contamination these samples. levels, measured per cent kernels infected, modest with mean levels above cereals...
The issue of food safety in Africa is one which interacts with and frequently subjugate to issues security, especially geographic areas where shortages are caused by recurrent natural weather phenomena such as drought. In addition, many subsistence farming communities reliant on the consumption home‐grown crops, irrespective quality considerations normally applied developed world. Nevertheless, some African governments have instituted regulations control mycotoxin, aflatoxin, contamination...
A liquid chromatographic (LC) method for simultaneous determination of fumonisins B1 (FB1), B2 (FB2), and B3 (FB3) in corn was subjected to a collaborative study involving 12 participants from 10 countries, which the accuracy reproducibility characteristics were established. Mean analyte recoveries ranged 81.1 84.2% FB1 (at spiking range 500 8000 ng/g), 75.9 81.9% FB2 200 3200 75.8 86.8% FB3 100 1600 ng/g). The valid data statistically evaluated after exclusion outliers. Relative standard...
Abstract Three recently described and toxlcologlcally Important Fusarlum mycotoxins, fumonisln B1 (FB1), B2 (FB2), B3 (FB3), are the major fumonisins produced In cultures of F. monlllforme, a fungus that occurs worldwide on corn. Contamination food feed with monlllforme has been associated number diseases both animals humans. Aspects reported liquid chromatographic method for determination FB1 FB2 in corn, including Initial extraction, extract purification, stability derivatives, were...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLevels of fumonisins B1 and B2 in feeds associated with confirmed cases equine leukoencephalomalaciaPieter G. Thiel, Gordon S. Shephard, Eric W. Sydenham, Walter F. O. Marasas, Paul E. Nelson, Terrance M. WilsonCite this: J. Agric. Food Chem. 1991, 39, 1, 109–111Publication Date (Print):January 1991Publication History Published online1 May 2002Published inissue 1 January...
The fumonisins are mycotoxins produced mainly by Fusarium verticillioides and F. proliferatum in maize, the predominant cereal staple for subsistence farming communities southern Africa. In order to assess exposure these Bizana (now known as Mbizana) Centane magisterial areas of former Transkei region Eastern Cape Province South Africa, actual maize consumption different age groups was measured. 1-9 years (n = 215) 10-17 240) years, mean (+/-standard error) 246 +/- 10.8 368 10.3 g per person...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFumonisin concentrations in Brazilian feeds associated with field outbreaks of confirmed and suspected animal mycotoxicosesEric W. Sydenham, Walter F. O. Marasas, Gordon S. Shephard, Pieter G. Thiel, Elisa Y. HirookaCite this: J. Agric. Food Chem. 1992, 40, 6, 994–997Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://doi.org/10.1021/jf00018a016RIGHTS & PERMISSIONSArticle...