Summary Neutrophil extracellular traps (NETs) are networks of DNA, histones, and proteolytic enzymes produced by activated neutrophils through different mechanisms. NET formation is promoted platelets can in turn activate platelets, thus favoring thrombotic processes. NETs have been detected venous arterial thrombosis, but data stroke scarce. The aim this study was to evaluate the plasma patients with acute ischemic their potential association baseline clinical characteristics, severity,...

Erythrocytes are known to influence hemostasis. Bleeding times prolonged in anemia and corrected by normalizing the hematocrit. We now demonstrate that intact erythrocytes modulate biochemical functional responsiveness of activated platelets. A two-stage procedure, permitting studies cell-cell interactions independently evaluating platelet activation recruitment within 1 min stimulation, was developed. increased serotonin release despite aspirin treatment, enzymatic adenosine diphosphate...

Aspirin (acetylsalicylic acid, ASA) is widely used for secondary prevention of ischemic vascular events, although its protection only occurs in 25% patients. We previously demonstrated that platelet reactivity enhanced by a prothrombotic effect erythrocytes thromboxane-independent manner. This diminishes the antithrombotic therapeutic potential ASA. Recent data from our laboratory indicate also contains an ASA-sensitive component. In accordance with this observation, intermittent treatment...

summary The aim of this study was to evaluate the presence pathological primitive reflexes and their effects on dental caries oral hygiene in cerebral‐palsied individuals. A group 124 non‐institutionalized patients (57 males) attending Lar Escola Sao Francisco Rehabilitation Center, who had a medical diagnosis spastic CP (age range 3–17 years, mean ± s.d. = 8·6 4·3) were selected for clinical evaluation according WHO ( Oral health surveys: basic methods , WHO, Geneva, 1997) using index...

The aim of this study was to evaluate the profile and burden caregivers children/adolescents with without Down syndrome. evaluations were performed through questionnaires about (Zarit Burden Interview) children/adolescents. These applied 168 caregivers. chi-square test, Fisher's exact analysis variance used a significance level set at = 5%. Both groups composed 84 participants, disabled group had significantly higher percentage females (p 0.001), those in 41-60 age < who no occupation low...

Abstract Aims To evaluate the quality of life (QoL) and burden primary caregivers children young adults (PCCYAs) with without disabilities. Methods A cross‐sectional study was carried out sample composed 336 PCCYAs cerebral palsy (CP; n = 84), Down syndrome (DS; autism spectrum disorder (ASD; disabilities (control group: CG matched by gender age. The assessed Zarit Burden Interview (ZBI), whereas QoL using WHOQOL‐BREF instrument. Results presented better results compared to groups...

J Oral Pathol Med (2011) 40: 576–581 Background: Disturbances in homeostatic functions have been observed individuals with cerebral palsy (CP), possibly resulting from autonomic dysfunction. Salivary flow rate and saliva composition are controlled by the nervous system, CP exhibit alterations salivary parameters that suggest impairment. This study aimed to investigate cardiac as indicative of disturbances, associated changes individuals. Methods: Ninety were compared 35 sibling volunteers no...

Few studies specifically focus on elderly splenectomized immune thrombocytopenia (ITP) patients. Older patients with ITP and excellent health are often excluded from surgery splenectomy. We aimed to compare the safety efficacy of splenectomy in non-elderly examine effect age therapeutic response.We carried out a retrospective analysis series 218 who had undergone for ITP. compared data group (≥65 yrs, 57 patients) young (<65 162 patients).Surgical technique (laparoscopy or open laparotomy...

The aim of the present study was to evaluate use Picture Exchange Communication System (PECS) in individuals with autism spectrum disorder (ASD) order facilitate patient-professional communication during preventive procedures. In this study, 26 patients ASD, between 5 and 19 years age (10±3.3 y), were divided into two groups: G1 (n = 13) no previous experience dental treatment, G2 13), such experience. initial approach followed principles Son-Rise Program®. seven PECSs presented routine...

ABSTRACT Background The sense of coherence (SOC) is important for the well‐being, especially mothers children and adolescents with cerebral palsy (CP). Objective This study aimed to investigate relationship between Mother's SOC oral health status in children/adolescents without CP. Materials Method A paired cross‐sectional was conducted 102 CP, their respective mothers. Participants were aged 3 17 years, matched by sex age. Antonovsky's questionnaire (SOC‐13) answered from both groups,...

The effect of low-intensity laser (GaAsAl) irradiation on bone repair in the femurs mice was investigated. An experimental model hole injury with surgery drills used 20 mouse followed by a study low-energy repair. divided into two groups. first (10 left femurs) received immediately after and for different time intervals (24, 48, 72 h). right (control group) underwent but no irradiation. rats were sacrificed 14 days results analyzed using quantitative histometrical method. Mann-Whitney test...

Abstract This study was conducted to examine the oral condition and salivary microbiological parameters associated with dental caries in 62 children cerebral palsy, who came from households of low socioeconomic status (Study Group). group had mixed (6 11 years old) permanent (11 16 dentition. Dental examinations were performed measure caries, plaque index, levels mutans streptococci lactobacilli, flow rate, pH stimulated saliva, buffer capacity saliva. A 67 non‐handicapped similar...

The aim of this study was to investigate caries experience in individuals with cerebral palsy (CP) who have oromotor dysfunction and relate it age dietary consistency. Noninstitutionalized CP (n = 108) aged 4-19 years (mean: 10 years, 1 month +/- SD 4 5 months) were recruited for study. Subjects severely impaired (35.2%) had orofacial motor most frequently, followed by those slightly affected (27.7%), moderately (20.4%), very (16.7%). Age a statistically significant factor (p= 0.007), the...

Individuals with special needs exist throughout the world. The last demographic census (IBGE, 2002) in Brazil indicated that 14.5% of total population (24.5 million) present some type impairment. This study aimed to evaluate prevalence dental trauma (DT) individuals and first attendance by a surgeon patients admitted care clinic School Dentistry Universidade Paulista (UNIP), Brazil, between 2001 2005.The sample included 544 aged 1-20 years old (mean 10.7 ± SD 5.3). Patient medical records...

Summary Among the conditions that classify individuals as special needs patients are those resulting from neurological sequelae, particularly cerebral palsy (CP), which is a disorder of high prevalence. Innumerable alterations can be found in with CP but inability to control striated muscles, due damages suffered by central nervous system, should emphasized. Changes tonus, speed and strength oral reduction mandibular mobility amplitude difficulty passively seal lips characteristics observed...

The aim of this study was to investigate the correlation between caries prevalence in individuals with cerebral palsy (CPG) and burden on their caregivers (CGCP) compared nondisabled (CG) (CGCG). In a cross-sectional assessment, 65 subjects were evaluated for prevalence. CGCP answered Caregiver Burden Scale (CBS) questionnaire. Using same methodology, 58 CG CGCG replied had statistically significant higher scores general strain, isolation, disappointment, environment, total using CBS CPG...

Abstract – Background: Cerebral palsy (CP) is one of the most frequent conditions encountered in daily practice dentists who treat special‐needs individuals and it seems that traumatic dental injuries are often present these cases. The aim this study was to investigate describe prevalence related injury (TDI) with CP attending rehabilitation treatment at Lar Escola Sao Francisco Rehabilitation Center São Paulo, Brazil Material Methods: sample included 100 a medical diagnosis (SG) aged 1–15...

Abstract Objective To study the correlation between caries experience in individuals with cerebral palsy (CP) and quality of life their primary caregivers. Materials methods Sixty‐five non‐institutionalized individuals, presenting CP, aged 2–21 years old, were evaluated for experience. Their respective caregivers 20–74 old answered Short Form 36 (SF‐36) health survey Independence Measure Children. Fifty‐eight non‐disabled (ND group), caregivers, 25–56 submitted to same evaluation process as...

doi: 10.1111/j.1741‐2358.2012.00623.x Pulp sensibility test in elderly patients Background: The ageing process transforms the histological composition of dental pulp and may affect response to tests. Objectives: aim this study was assess influence age on time pain intensity. Material methods: Fifty 50 young were selected. Different classes teeth evaluated. performed with a refrigerant spray. measured seconds intensity assessed by visual analogue scale. Results: Spearman coefficient...

To review the literature regarding use of surgical lasers in hemangioma treatment and to report a clinical case involving diode laser.Hemangiomas are benign vascular proliferations consisting numerous capillary structures especially common on tongue, lips, jugal mucous membrane, gums. A number modalities have been proposed for treatment.The patient was referred evaluation complaining chewing difficulty because swelling right area upper lip, with no previous trauma. The lesion located...

Previous studies reported alterations in salivary flow rate and biochemical parameters of saliva cerebral palsy (CP) individuals; however, none these considered the type neuromotor abnormality among CP individuals, thus it remains unclear whether different anatomical extended regions brain lesions responsible for neurological damage might include disruption regulatory mechanism secretion as part encephalopathy. The aim this study was to evaluate rate, pH buffer capacity individuals with CP,...

J Oral Pathol Med (2011) 40: 582–586 Background: Unstimulated whole salivary parameters have been identified as potential markers of hydration status. Reduced flow rate and increased osmolality shown to be useful identify dehydration, even when minimal loss body water occurs. This study aimed evaluate whether unstimulated from individuals with cerebral palsy correlate plasma urine osmolality. Methods: Thirty-five male female children, aged 9–13 years old, diagnosed were compared 27...