Wengen Zhu

ORCID: 0000-0002-1280-0158
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Function and Risk Factors
  • Cardiac Arrhythmias and Treatments
  • Heart Failure Treatment and Management
  • Cardiac electrophysiology and arrhythmias
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac pacing and defibrillation studies
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Ion channel regulation and function
  • Cardiovascular Effects of Exercise
  • Cardiac Health and Mental Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiac Imaging and Diagnostics
  • Cardiomyopathy and Myosin Studies
  • Acute Ischemic Stroke Management
  • COVID-19 Clinical Research Studies
  • Hormonal Regulation and Hypertension
  • Long-Term Effects of COVID-19
  • Cardiovascular Disease and Adiposity
  • Cardiac Valve Diseases and Treatments
  • Potassium and Related Disorders
  • Diabetes Treatment and Management
  • Retinal Diseases and Treatments
  • Blood Pressure and Hypertension Studies
  • Glycosylation and Glycoproteins Research

The First Affiliated Hospital, Sun Yat-sen University
2017-2025

Sun Yat-sen University
2017-2025

Shanghai Jiao Tong University
2020-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

National Health and Family Planning Commission
2021

Shanghai Ninth People's Hospital
2020

Nanchang University
2014-2019

Second Affiliated Hospital of Nanchang University
2014-2019

Peking University First Hospital
2016

Peking University
2016

Ischemia/reperfusion (I/R) injury is a life-threatening vascular emergency following myocardial infarction. Our previous study showed cardioprotective effects of metformin against I/R injury. In this study, we further examined the involvement AMPK mediated activation NLRP3 inflammasome in effect metformin. Myocardial was simulated rat heart Langendorff model and neonatal ventricle myocytes (NRVMs) were subjected to hypoxi/reoxygenation (H/R) establish an vitro model. Outcome measures...

10.18632/aging.202143 article EN cc-by Aging 2020-11-21

Abstract Objective The triglyceride–glucose (TyG) index has been shown to be a new alternative measure for insulin resistance. However, no study attempted investigate the association of TyG with incident atrial fibrillation (AF) in general population without known cardiovascular diseases. Methods Individuals diseases (heart failure, coronary heart disease, or stroke) from Atherosclerosis Risk Communities (ARIC) cohort were recruited. baseline was calculated as Ln [fasting triglycerides...

10.1186/s12933-023-01777-9 article EN cc-by Cardiovascular Diabetology 2023-05-18

Osteoporosis is a highly prevalent disease with distinct sex pattern. We aimed to estimate the specific incidence, prevalence, and disability-adjusted life (DALYs) years of osteoporosis between 1990 2019, additional predictions from 2020 2034. collected burden data Global Burden Disease study covering through 2019 in 204 countries territories. The included information on number incident cases osteoporosis, DALYs, age-standardized incidence rates (ASIR), prevalence (ASPR) DALYs rates....

10.1007/s12603-023-1971-4 article EN cc-by-nc-nd The journal of nutrition health & aging 2023-09-01

Background ChatGPT, an artificial intelligence (AI) based on large-scale language models, has sparked interest in the field of health care. Nonetheless, capabilities AI text comprehension and generation are constrained by quality volume available training data for a specific language, performance across different languages requires further investigation. While harbors substantial potential medicine, it is imperative to tackle challenges such as formulation clinical care standards;...

10.2196/48514 article EN cc-by JMIR Medical Education 2023-12-11

Abstract Background Epicardial adipose tissue (EAT) has been suggested to exert deleterious effects on myocardium and cardiovascular disease (CVD) consequence. We evaluated the associations of EAT thickness with adverse outcomes its potential mediators in community. Methods Participants without heart failure (HF) who had undergone cardiac magnetic resonance (CMR) measure over right ventricular free wall from Framingham Heart Study were included. The correlation 85 circulating biomarkers...

10.1186/s12916-023-02836-4 article EN cc-by BMC Medicine 2023-03-29
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