William M. Burke

ORCID: 0000-0002-1288-4590
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About
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Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Ovarian cancer diagnosis and treatment
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Cervical Cancer and HPV Research
  • Minimally Invasive Surgical Techniques
  • Intraperitoneal and Appendiceal Malignancies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Ectopic Pregnancy Diagnosis and Management
  • BRCA gene mutations in cancer
  • Maternal and fetal healthcare
  • Colorectal and Anal Carcinomas
  • Pelvic and Acetabular Injuries
  • Palliative Care and End-of-Life Issues
  • Economic and Financial Impacts of Cancer
  • Gynecological conditions and treatments
  • Multiple and Secondary Primary Cancers
  • Sarcoma Diagnosis and Treatment
  • Clinical practice guidelines implementation
  • Cancer survivorship and care
  • Diversity and Career in Medicine
  • Global Cancer Incidence and Screening
  • Cancer Risks and Factors
  • Forensic Toxicology and Drug Analysis
  • Innovations in Medical Education

Stony Brook School
2024

Stony Brook University
2017-2024

Stony Brook Medicine
2019-2024

The University of Sydney
2024

Stony Brook University Hospital
2018-2023

University of California, Davis
2023

Medical College of Wisconsin
2023

American Congress of Obstetricians and Gynecologists
2023

Creighton University
2023

State University of New York
2023

Although robotically assisted hysterectomy for benign gynecologic conditions has been reported, little is known about the incorporation of procedure into practice, its complication profile, or costs compared with other routes hysterectomy.To analyze uptake hysterectomy, to determine association between use robotic surgery and rates abdominal laparoscopic compare in-house complications vs procedures.Cohort study 264,758 women who underwent disorders at 441 hospitals across United States from...

10.1001/jama.2013.186 article EN JAMA 2013-02-19

To perform a population-based analysis comparing the performance of 1988 and 2009 International Federation Gynecology Obstetrics (FIGO) staging systems.Women with endometrioid adenocarcinoma uterus treated between 2006 recorded in Surveillance, Epidemiology, End Results database were analyzed. Women classified based on FIGO systems. Major changes system include: 1) classification patients stage IA IB tumors as IA; 2) elimination IIA; 3) stratification IIIC into pelvic nodes only (IIIC1) or...

10.1097/aog.0b013e3181f39849 article EN Obstetrics and Gynecology 2010-10-23

10.1016/s1074-3804(05)60085-0 article EN The Journal of the American Association of Gynecologic Laparoscopists 2004-11-01

Purpose Use of robotics in oncologic surgery is increasing; however, reports safety and efficacy are from highly experienced surgeons centers. We performed a population-based analysis to compare laparoscopic hysterectomy robotic for endometrial cancer. Patients Methods The Perspective database was used identify women who underwent minimally invasive cancer 2008 2010. Morbidity, mortality, cost were evaluated using multivariable logistic linear regression models. Results identified 2,464...

10.1200/jco.2011.36.7508 article EN Journal of Clinical Oncology 2012-01-31

Oophorectomy is commonly performed in premenopausal women with endometrial cancer who undergo hysterectomy. The benefits of oophorectomy this setting are unknown, and the procedure subjects to long-term sequelae estrogen deprivation. We examined safety ovarian preservation young underwent hysterectomy.Women < or = 45 years age stage I recorded from 1988 2004 Surveillance, Epidemiology, End Results Database were examined. developed Cox proportional hazards models Kaplan-Meier curves compare...

10.1200/jco.2008.19.8150 article EN Journal of Clinical Oncology 2009-01-27

While minimally invasive surgery has improved outcomes for hysterectomy, the procedure requires removal of uterus through small incisions. Morcellation, or fragmentation into smaller pieces, is one method to remove uterus. Recently, concern been raised that morcellation may result in spread undetected malignancies.1 Despite commercial availability electric power morcellators 2 decades, accurate estimates prevalence malignancy at time (herein referred as morcellation) are lacking,1,2 with...

10.1001/jama.2014.9005 article EN JAMA 2014-07-22

Abstract BACKGROUND: Surgical management of ovarian cancer consists hysterectomy with bilateral oophorectomy. In young women, this results in the loss reproductive function and estrogen deprivation. current study, authors examined safety fertility‐conserving surgery premenopausal women epithelial cancers. METHODS: Women aged ≤50 years stage IA or IC who were registered Surveillance, Epidemiology, End Results database examined. Patients underwent oophorectomy compared those conservation. A...

10.1002/cncr.24461 article EN Cancer 2009-08-10

To estimate the influence of surgical volume on outcome and resource utilization for laparoscopic hysterectomy benign indications.Patients who underwent from 2000 to 2010 recorded in a commercial database were analyzed. Patients stratified into tertiles according number procedures performed by their surgeons at hospital. The surgeon hospital perioperative morbidity was examined using multivariable regression models.A total 124,615 patients identified. overall complication rate decreased 6.2%...

10.1097/aog.0b013e318248f7a8 article EN Obstetrics and Gynecology 2012-03-22

To evaluate the current patterns of use minimally invasive surgical procedures, including traditional, robotic-assisted, and single-port laparoscopy, by Society Gynecologic Oncology (SGO) members to compare results those our 2004 2007 surveys.The were surveyed through an online or mailed-paper survey. Data analyzed compared with prior surveys.Four hundred six (32%) 1279 SGO responded. Eighty-three percent respondents (n = 337) performed traditional laparoscopic surgery (compared 84% in 91%...

10.1097/igc.0000000000000450 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2015-04-10

To assess the relation of ventricular arrhythmias to myocardial K(+) movement during ischemia, we placed an electrode catheter in left anterior descending coronary artery for thrombus production intact anesthetized dogs. (85)Kr injections distal permitted serial blood flow measurements. Animals Group I with a moderate reduction exhibited no arrhythmia or egress K(+). In II, marked was accompanied by injury potential and loss from ischemic site, before tachycardia. Therapeutic interventions...

10.1172/jci105657 article EN Journal of Clinical Investigation 1967-10-01

BACKGROUND Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM nongynecologic melanoma (NGM) subtypes with objective of identifying novel, targetable biomarkers. METHODS In total, 2304 samples malignant that were submitted to Caris Life Sciences 2009 2015 reviewed. situ hybridization immunohistochemistry used assess copy numbers protein expression selected genes. Sequenced variants analyzed using a...

10.1002/cncr.30473 article EN Cancer 2016-12-27

To examine relative survival (a metric that incorporates changes in within a population) women with ovarian cancer from 1975 to 2011.Women diagnosed 2011 and recorded the National Cancer Institute's Surveillance, Epidemiology, End Results database were examined. Relative survival, estimated as ratio of observed patients (all-cause mortality) expected comparable group general population, was matched main factors are considered affect patient such age, calendar time, race. Hazard ratios...

10.1097/aog.0000000000000854 article EN Obstetrics and Gynecology 2015-05-07

Despite the lack of efficacy data, robotic-assisted surgery has diffused rapidly into practice. Marketing to physicians, hospitals, and patients been widespread, but how this marketing contributed diffusion technology remains unknown.To examine effect regional hospital competition financial status on use for 5 commonly performed procedures.A cohort study 221 637 who underwent radical prostatectomy, total nephrectomy, partial hysterectomy, or oophorectomy at 1370 hospitals in United States...

10.1001/jamasurg.2015.5508 article EN JAMA Surgery 2016-02-17

In Brief OBJECTIVE: To perform an econometric analysis to examine the influence of procedure volume, variation in hospital accounting methodology, and use various analytic methodologies on cost robotically assisted hysterectomy for benign gynecologic disease endometrial cancer. METHODS: A national sample was used identify women who underwent laparoscopic or indications cancer from 2006 2012. Surgeon volume were classified as number procedures performed before index surgery. Total costs well...

10.1097/aog.0000000000000244 article EN Obstetrics and Gynecology 2014-04-07

Despite the potential benefits of minimally invasive hysterectomy for uterine cancer, population-level data describing procedure's safety in unselected patients are lacking. We examined use surgery and association between route procedure long-term survival.We used SEER-Medicare database to identify women with stage I-III cancer who underwent from 2006 2011. Patients abdominal were compared those had (laparoscopic robot-assisted). Perioperative morbidity, adjuvant therapy, survival after...

10.1200/jco.2015.65.3212 article EN Journal of Clinical Oncology 2016-02-02

Black women with endometrial cancer have been more likely to die than white patients. The authors examined factors associated the poor outcome for black uterine corpus tumors and analyzed whether these characteristics changed over time based on year of diagnosis.The neoplasms recorded from 1988-2004 in Surveillance, Epidemiology End Results (SEER) Database. developed Cox proportional hazards models examine effect race survival stratified by diagnosis into 3 groups: 1988-1993, 1994-1998,...

10.1002/cncr.24160 article EN Cancer 2009-02-09
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