A5001570863- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Probiotics and Fermented Foods
- Contact Dermatitis and Allergies
- Infant Nutrition and Health
- Glycosylation and Glycoproteins Research
- Insect and Pesticide Research
- Protein Hydrolysis and Bioactive Peptides
- Bee Products Chemical Analysis
- Proteins in Food Systems
- Fermentation and Sensory Analysis
- Insect and Arachnid Ecology and Behavior
- Meat and Animal Product Quality
- Polyamine Metabolism and Applications
- Microbial bioremediation and biosurfactants
- Identification and Quantification in Food
- Monoclonal and Polyclonal Antibodies Research
- Horticultural and Viticultural Research
- Antimicrobial Peptides and Activities
- Breastfeeding Practices and Influences
- GABA and Rice Research
- Asthma and respiratory diseases
- Animal Genetics and Reproduction
- RNA modifications and cancer
- Toxin Mechanisms and Immunotoxins
Institute of Sciences of Food Production
2014-2025
National Research Council
2013-2025
Cereal Research Centre
2018
Bitron (Italy)
2018
Food Technology Research Unit
2018
Environment Park
2003-2016
National Academies of Sciences, Engineering, and Medicine
2011
University of Turin
2001-2007
Azienda Ospedaliero Universitaria San Giovanni Battista
2007
Istituto Superiore di Sanità
2005
Integrin-mediated cell adhesion cooperates with growth factor receptors in the control of proliferation, survival, and migration. One mechanism to explain these synergistic effects is ability integrins induce phosphorylation receptors, for instance epidermal (EGF) receptor. Here we define some aspects molecular mechanisms regulating integrin-dependent EGF receptor phosphorylation. We show that early phases associate on membrane a macromolecular complex including adaptor protein p130Cas c-Src...
Successful therapy in cow's milk protein allergy rests on completely eliminating proteins from the child's diet: it is thus necessary to provide a replacement food. This prospective study investigated tolerance of donkey's population 46 selected children with allergy, for whom was not possible use any substitute. Thirty‐eight (82.6%) liked and tolerated at challenge entire duration follow‐up. Catch‐up growth observed all subjects deficit during challenge. The degree cross‐reactivity...
The Holder method is the recommended pasteurization for human milk banks, as it ensures microbiological safety of (HM). loss some biologically active components, due to heat treatment, a main limit diffusion donor HM. High-temperature short-time (HTST) may be an alternative maintain nutritional and immunological quality aim present study was compare impact HTST on HM protein profile. patterns HTST-treated raw were similar. modified bile salt-stimulated lipase, lactoferrin components immune...
Abstract All fermented foods are subject to the risk of biogenic amine contamination. Histamine and tyramine among most toxic amines for consumers' health, exerting undesirable effects on central nervous vascular systems, but putrescine cadaverine can also compromise organoleptic properties contaminated foods. These compounds produced by fermenting microbial flora that decarboxylate amino acids amines. Little is known factors which induce biosynthesis decarboxylating enzymes and/or modulate...
The recent availability of the honey-bee Apis mellifera genome and trascriptome both female castes, has stimulated new efforts in investigating protein composition royal jelly (RJ), its role caste differentiation quality typicality by a proteomic approach. This study is aimed to separate identify proteins detect some them pollen-bread using two-dimensional gel electrophoresis, mass spectrometry de novo sequencing. All identified belonged genome. Apalbumin 1 was also confirmed be present...
Abstract Milk fat globule membrane (MFGM) contains proteins derived from the apical of secreting epithelial cells mammary gland. Between 2–4% total human milk protein content is associated with fraction, as MFGM proteins. While have very low classical nutritional value, they play important roles in various cell processes and defence mechanisms for newborn. To date, fewer than 30 been identified characterized, either by immunological methods or Edman sequencing mass spectrometry. This study...
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by rapid progression, invasiveness, and resistance to treatment. It the fourth leading cause of cancer death with 2% 5-year survival rate. Biomarkers for its early detection are lacking. This study was designed use proteomics-based approach as means identifying antigens that elicit humoral response in PDAC patients. Antibodies against PDAC-associated useful diagnosis therapy. Proteins from cell lines were...
ABSTRACT Wild canids and domestic dogs are the main reservoir of zoonotic visceral leishmaniasis (VL) caused by Leishmania infantum (syn.: chagasi ). Serological diagnosis VL is therefore important in both human dog from a clinical epidemiological point view. Routine traditionally carried out immunofluorescent antibody test (IFAT), which laborious difficult to standardize interpret. In last decade, however, several specific antigens have been characterized, allowing development...
According to European Union Regulation EC 1531/2001, olive oil labelled as "extra-virgin" should be cold-pressed and contain no refined or from other oleaginous seeds nuts. Adulteration of extra virgin (EVOO) with hazelnut (HAO) is a serious concern both for suppliers consumers. The high degree similarity between the two fats complicates detection low percentages HAO in EVOO. Many analytical approaches have been developed recent years trace EVOO, principally based on chromatographic...
Upon combining bidimensional electrophoresis with monodimensional separation, a more comprehensive analysis of the milk fat globule membrane has been obtained. The proteomic profile caprine globules revealed presence butyrophilin, lactadherin and perilipin as major proteins, they were also associated to bovine human membranes. Xanthine dehydrogenase/oxidase detected only in gels. Biological activity evaluated Caco2-cells, representative model intestinal barrier. increase cell viability was...
Lactic acid bacteria (LAB) potential in the food industry and biotechnological sector is a well-established interest. LAB counteracting especially food-borne infections has received growing attention, but despite being road full of promises yet poorly explored. Furthermore, ability to produce antimicrobial compounds, both by ribosomal synthesis decrypting them from proteins, high value when considering impact multidrug resistant strains. The 14 food-derived lactic strains been investigated...