Improvement in drug response and reduction of toxicity were observed after continuous intrahepatic arterial infusion mytomycin-C (MMC) 5-fluorouracil (5-FU) 15 26 patients with primary or metastatic carcinoma the liver. Serum bilirubin values 10 mg/100 ml absence ascites, extreme cachexia impending hepatic failure used as criteria for admission these into study. The given MMC a dose 0.08 mg/kg on day 1,5-FU 8-10 days 2-5, 6. This schedule was reinitiated 8 total mean duration 18 days....

Abstract Background Tentorium cerebelli divide cranial cavity into supratentorial and infratentorial compartment. Tentorial notch is a gap in tentorium located centrally anteriorly, related to upper brainstem, first six nerves, cerebrum, cerebellum. The aim of this study was analyze morphometric variation tentorial anatomy autopsy computed tomography (CT) head injury patients find out correlation between uncal herniation changes over brainstem surface case herniation. Materials Methods...

Orbital roof fractures after a blunt injury are an uncommon complication of trauma. Traumatic encephaloceles in the orbital cavity even rarer, with only 15 cases published till date. Raised intraorbital pressure leading to irreversible damage optic nerve can be prevented by early diagnosis and management. computed tomography (CT) thin axial coronal sections is helpful trauma patients concurrent Decompression key step surgical treatment should performed every case. Repairing has avoid...

Context: Spontaneous intracerebral haemorrhage (ICH) accounts for 4–14% of all strokes and has a high mortality rate 30–50% during the first month. Management large hematomas is controversial, with some advocating medical management while others favoring surgical evacuation.Aim: This study was undertaken to compare outcome patients spontaneous supratentorial hemorrhage (SSICH) managed or without evacuation.Settings Design: Four hundred eighty-two SSICH admitted from September 2013 August...

Central nervous system (CNS) tuberculosis commonly manifests as tubercular meningitis. CNS tuberculomas are more common intracranially and less frequently involve the spinal cord. Combination of intramedullary with intracranial is extremely rare. We report a case concurrent occurrence tuberculoma multiple in young 16-year-old boy, who presented two weeks history paresthesias weakness lower limbs diminution vision left eye, had been treated for pulmonary tuberculosis. Magnetic resonance...

<b><i>Background:</i></b> Extradural hematoma (EDH) is one of the most common causes mortality and morbidity after traumatic brain injury in pediatric patients. Early surgical intervention these patients produces excellent results. <b><i>Objective:</i></b> We reviewed experience at our center, examining presenting symptomatology outcome analysis. <b><i>Materials Methods:</i></b> A retrospective study 228 EDH from July...

Spinal intramedullary tuberculoma (SIMT) is rare, accounting for 2/100,000 cases of tuberculosis and only 0.2% all central nervous system(CNS) tuberculosis. We share our experiences 11 this entity improving diagnosis conceptualize the management rare disease.The clinical profile, radiological data SIMT which were managed either conservatively or by surgical intervention during last 27 years (1987-2014) analysed.Male:female ratio was 1.75:1. Five had associated pulmonary Koch's. Most common...

Medulloblastoma is a common tumor of the posterior fossa, representing 20-25% all pediatric neoplasms. It commonly occurs in midline (cerebellar vermis) and rarely at cerebellopontine angle. Most them are intra-axial, an extra-axial location this very rare. Extra-axial angle medulloblastoma extremely uncommon has never been reported infant. We report angle<b> </b>medulloblastoma 1-year-old child.

<b><i>Background:</i></b> Growing skull fracture (GSF)/pseudomeningocele is a rare complication of head injury in children. Post-traumatic intradiploic arachnoid cyst (PTIAC) variant but it extremely rare. PTIACs are usually asymptomatic or with mild symptoms like headache. The rupture PTIAC due to re-trauma leading pseudomeningocele formation has not been seen reported before. <b><i>Patient and Method:</i></b> We present case occipital where...

Background: Ventriculoperitoneal shunt (VP shunt) surgery is one of the most common procedures being performed in pediatric age group neurosurgical centers worldwide. Although considered a simple surgery, complications have made it difficult to manage long term. In this study, we describe our experiences managing unusual procedure children. Materials and Methods: This retrospective study enrolled 13 cases having related VP who presented us from August 2013 2019. All were evaluated for their...

Traumatic pseudoaneurysm of the superficial temporal artery is a very rare lesion and usually presents as painless pulsatile mass in region few weeks after trauma. Though first described by Bartholin 1740, infrequent incidence sometimes perplexing presentation still warrants need for awareness its diagnosis. We report case traumatic that presented blunt trauma to head. also review anatomical peculiarities pathophysiology facilitates formation optimal approach diagnosis management lesion.

Primary non-Hodgkin's lymphoma (NHL) of the cranium with extra- and intracranial extension without systemic or skeletal manifestation in a non-immunocompromised patient is extremely rare. These lesions are most time misdiagnosed because they mimic other conditions like meningioma. Here, we report case presented huge bulky scalp mass which on magnetic resonance imaging (MRI) brain showed involvement scalp, cranial vault, meninges, parenchyma, mimicking After gross total resection, biopsy CD...

Keyhole surgery recently evolved as a minimal invasive surgical approach for treatment of anterior circulation aneurysm. This review was done to evaluate the keyhole aneurysms, their indications, advantages, technical limitations, complications and avoidance. The literature performed with phrase "keyhole aneurysm" search term in PubMed central, Medline, Google scholar Embase data base identify all articles published till December 2020. Out 113 searched, 22 were included this after screening...

<br>Abdominal complications after ventriculoperitoneal (VP) shunt surgery for hydrocephalus have been known to occur. The more common include peritoneal pseudocyst, obstruction of the lower end, and infection. Perforations intra-abdominal hollow viscera leading spontaneous extrusions catheter via natural orifices also reported. A rarer phenomenon still is migration end VP through anterior abdominal wall, formation a umbilical fistula at site unrelated surgical site. Eight cases described in...

Interfrontal encephalocele is one of the rare varieties anterior encephalocele, and a giant interfrontal extremely rare. The authors could find only case report in literature. Anterior encephaloceles are more prevalent South-East Asia some northern parts India. Giant poses great challenge to neurosurgeons neuroanesthetists during surgery, as these infants usually have low birth weight large sac, thus making infant prone hypothermia blood loss among other risks. We encountered patient with...

Introduction: To study the impact COVID-19-related lockdown on persons with disabilities (PWDs), we conducted a telephonic survey of (n = 120) participants in four major cities India (Delhi, Hyderabad, Jodhpur, and Patna). The was twice-once Phase 2 (April 15, 2020–May 3, 2020) again 5 (June 1, 2020–June 30, lockdown. Methods: A questionnaire prepared for this PWDs to understand following: participants' understanding prevention COVID-19 handwashing technique, use facemasks, social distancing...

Abstract Background Clinicians treating patients with head injury often take decisions based on their assessment of prognosis. Assessment prognosis could help communication a patient and the family. One most widely used clinical tools for such prediction is Glasgow coma scale (GCS); however, tool has limitation regard to its use in who are under sedation, intubated, or influence alcohol psychoactive drugs. CT scan findings as status basal cistern, midline shift, associated traumatic...

<br>Distal migration of shunt is a very common occurrence. Proximal rare and possible pathophysiological mechanisms to explain this unusual complication rarely attempted. A 5-month-old child shunted for posttraumatic hydrocephalus presented 1.5 years later with raised intracranial pressure seizures. Imaging showed subdural hygroma, partial shunt/chamber. On endoscopy, choroid plexus was adherent tip some pericranial tissue found in the anchoring suture (intraventricularly displaced). Shunt...